MX170961B - Procedimiento para la preparacion de esteres epoxicos y substancias intermediarias preparadas mediante el mismo - Google Patents

Procedimiento para la preparacion de esteres epoxicos y substancias intermediarias preparadas mediante el mismo

Info

Publication number
MX170961B
MX170961B MX021143A MX2114390A MX170961B MX 170961 B MX170961 B MX 170961B MX 021143 A MX021143 A MX 021143A MX 2114390 A MX2114390 A MX 2114390A MX 170961 B MX170961 B MX 170961B
Authority
MX
Mexico
Prior art keywords
preparation
procedure
same
epoxy esters
substances prepared
Prior art date
Application number
MX021143A
Other languages
English (en)
Inventor
Wilford Lee Mendelson
Joseph Robert Flisak
Paul George Gassman
Ivan Lantos
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of MX170961B publication Critical patent/MX170961B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
    • C07C49/796—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/794—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring
    • C07C49/798—Ketones containing a keto group bound to a six-membered aromatic ring having unsaturation outside an aromatic ring containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a un procedimiento mejorado para la preparación de una cetona -epóxica quiral de la fórmula: III, que comprenden la reacción de un a cetona -insaturada de la fórmulaII: con ácido poliamino, un oxidante y una base en una mezcla de agua y un solvente orgánico en donde la mejora se logra mediante el uso de un solvente de hidrocarbono no aromático no clorado.
MX021143A 1989-06-14 1990-06-13 Procedimiento para la preparacion de esteres epoxicos y substancias intermediarias preparadas mediante el mismo MX170961B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/366,059 US5110959A (en) 1989-06-14 1989-06-14 Process for preparation of epoxy esters and intermediates prepared thereby

Publications (1)

Publication Number Publication Date
MX170961B true MX170961B (es) 1993-09-22

Family

ID=23441503

Family Applications (1)

Application Number Title Priority Date Filing Date
MX021143A MX170961B (es) 1989-06-14 1990-06-13 Procedimiento para la preparacion de esteres epoxicos y substancias intermediarias preparadas mediante el mismo

Country Status (5)

Country Link
US (1) US5110959A (es)
EP (1) EP0403252A3 (es)
JP (1) JPH0331272A (es)
MX (1) MX170961B (es)
PT (1) PT94375A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69113048T2 (de) * 1990-08-01 1996-02-22 Smithkline Beecham Corp Verfahren und zwischenprodukte für die herstellung von 2-hydroxy-3-sulfido-3-phenylpropansäuren.
AU705806B2 (en) * 1995-04-20 1999-06-03 Chirotech Technology Limited Asymmetric epoxides, their synthesis and use
US6228955B1 (en) * 1996-04-19 2001-05-08 Chirotech Technology, Ltd. Asymmetric epoxides, their synthesis and use
DE19855858A1 (de) * 1998-12-03 2000-06-08 Degussa Verfahren zur enantioselektiven Epoxidierung von C-C-Doppelbindungen
JP3784652B2 (ja) * 2001-02-21 2006-06-14 ペガサスミシン製造株式会社 ミシンの給油装置
DE10136485C1 (de) 2001-07-27 2003-03-06 Bayer Ag Polyaminosäure-katalysiertes Verfahren zur enantioselektiven Epoxidierung von alpha,ß-ungesättigten Eonen und alpha,ß-ungesättigten Sulfonen
DE10136131B4 (de) 2001-07-27 2004-02-12 Bayer Ag Polyaminosäure-katalysiertes Verfahren zur enantioselektiven Epoxidierung von α,β-ungesättigten Enonen und α,β-ungesättigten Sulfonen
DE10136132C2 (de) * 2001-07-27 2003-10-30 Bayer Ag Polyaminosäure-katalysiertes Verfahren zur enantioselektiven Epoxidierung von alpha,beta-ungesättigten Enonen und alpha,beta-ungesättigten Sulfonen
JP4534457B2 (ja) * 2002-09-25 2010-09-01 東ソー株式会社 光学活性エポキシ化合物類、及びその製造方法
JP4100555B2 (ja) 2002-12-11 2008-06-11 ペガサスミシン製造株式会社 オーバーロックミシンにおける上ルーパ機構の排油装置
US7781606B2 (en) * 2006-12-28 2010-08-24 Momentive Performance Materials Inc. Blocked mercaptosilane coupling agents, process for making and uses in rubber
JP5071905B2 (ja) * 2008-05-28 2012-11-14 国立大学法人東京農工大学 有機分子触媒、およびエポキシケトンの製造方法
EP3816155A1 (en) * 2013-08-23 2021-05-05 Virginia Commonwealth University Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896144A (en) * 1973-07-13 1975-07-22 American Cyanamid Co Preparation of 3,5-diphenyl-2-pyrazolin-4-ol, 3,5-diphenyl-pyrazole and the phenyl-substituted derivatives thereof
ATE90330T1 (de) * 1985-04-19 1993-06-15 Smithkline Beecham Corp Zwischenprodukte fuer die herstellung von leukotrien-antagonisten.

Also Published As

Publication number Publication date
EP0403252A3 (en) 1991-08-28
PT94375A (pt) 1991-02-08
US5110959A (en) 1992-05-05
EP0403252A2 (en) 1990-12-19
JPH0331272A (ja) 1991-02-12

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