MX163592B - Compuestos de polipeptido que tienen actividad liberadora de la hormona del crecimiento - Google Patents

Compuestos de polipeptido que tienen actividad liberadora de la hormona del crecimiento

Info

Publication number
MX163592B
MX163592B MX11845A MX1184588A MX163592B MX 163592 B MX163592 B MX 163592B MX 11845 A MX11845 A MX 11845A MX 1184588 A MX1184588 A MX 1184588A MX 163592 B MX163592 B MX 163592B
Authority
MX
Mexico
Prior art keywords
growth hormone
hormone releasing
releasing activity
polypeptide compounds
polypeptide
Prior art date
Application number
MX11845A
Other languages
English (en)
Inventor
Chang Yarling Bowers
Frank Alden Momany
Ching Hsong Chag
Wayne Livingston Cody
John Clark Hubbs
Charles Howard Foster
Original Assignee
Eastman Kodak Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Kodak Co filed Critical Eastman Kodak Co
Publication of MX163592B publication Critical patent/MX163592B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/12Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
MX11845A 1987-06-12 1988-06-10 Compuestos de polipeptido que tienen actividad liberadora de la hormona del crecimiento MX163592B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/060,877 US4839344A (en) 1987-06-12 1987-06-12 Polypeptide compounds having growth hormone releasing activity

Publications (1)

Publication Number Publication Date
MX163592B true MX163592B (es) 1992-06-04

Family

ID=22032299

Family Applications (1)

Application Number Title Priority Date Filing Date
MX11845A MX163592B (es) 1987-06-12 1988-06-10 Compuestos de polipeptido que tienen actividad liberadora de la hormona del crecimiento

Country Status (12)

Country Link
US (1) US4839344A (es)
EP (1) EP0434675B1 (es)
JP (1) JPH02503798A (es)
AU (1) AU606736B2 (es)
CA (1) CA1318463C (es)
DE (1) DE3883789T2 (es)
FI (1) FI94868C (es)
IE (1) IE62503B1 (es)
IL (1) IL86700A0 (es)
MX (1) MX163592B (es)
NZ (1) NZ225078A (es)
WO (1) WO1988009780A2 (es)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
DE68922602T2 (de) * 1988-01-28 1995-12-07 Polygen Holding Corp Polypeptide mit hormonwachstumsbefreiender wirkung.
JPH03502326A (ja) * 1988-01-28 1991-05-30 ポリゲン ホールディング コーポレイション 成長ホルモン放出活性を有するポリペプチド化合物類
WO1989010933A1 (en) * 1988-05-11 1989-11-16 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
GB8813356D0 (en) * 1988-06-06 1988-07-13 Ici Plc Polypeptide compounds
US5137872A (en) * 1989-09-18 1992-08-11 Pitman-Moore, Inc. Growth hormone-releasing factor analogs
US5872100A (en) * 1990-05-11 1999-02-16 Deghenghi; Romano Peptides containing D-2-Alkyl-Tryptophan
US5486505A (en) * 1990-07-24 1996-01-23 Polygen Holding Corporation Polypeptide compounds having growth hormone releasing activity
IL98910A0 (en) * 1990-07-24 1992-07-15 Polygen Holding Corp Polypeptide compounds having growth hormone releasing activity and pharmaceutical compositions containing them
US5663146A (en) * 1991-08-22 1997-09-02 Administrators Of The Tulane Educational Fund Polypeptide analogues having growth hormone releasing activity
CZ291798B6 (cs) * 1994-09-27 2003-05-14 Romano Deghenghi Peptidy, jejich použití a farmaceutický prostředek s jejich obsahem
US20020111461A1 (en) * 1999-05-21 2002-08-15 Todd C. Somers Low molecular weight peptidomimetic growth hormone secretagogues
US5798337A (en) * 1994-11-16 1998-08-25 Genentech, Inc. Low molecular weight peptidomimetic growth hormone secretagogues
WO1997022367A1 (en) * 1995-12-20 1997-06-26 Merck & Co., Inc. Radiolabeled growth hormone secretagogue
US5807985A (en) * 1996-06-11 1998-09-15 Deghenghi; Romano Oligopeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone
US5972895A (en) * 1996-12-11 1999-10-26 A. Glenn Braswell Composition and method for increasing growth hormone levels
US5925618A (en) * 1997-03-06 1999-07-20 American Cyanamid Company Peptides useful as somatostatin antagonists
JPH10251296A (ja) * 1997-03-06 1998-09-22 American Cyanamid Co ソマトスタチン拮抗薬として有用なペプチド
AU7906998A (en) 1997-06-20 1999-01-04 Novo Nordisk A/S Compounds with growth hormone releasing properties
EP1506969B1 (en) 1998-01-16 2010-06-09 Helsinn Therapeutics (U.S.), Inc. Compounds with growth hormone releasing properties
CN1203846C (zh) 1998-03-19 2005-06-01 布里斯托尔-迈尔斯斯奎布公司 高溶解性药物的双相控释递送系统和方法
US6919315B1 (en) 1998-06-30 2005-07-19 Novo Nordisk A/S Compounds with growth hormone releasing properties
US6610496B1 (en) * 1998-07-08 2003-08-26 University Of Maryland, College Park Prediction of growth performance and composition in animals, including cattle, from response to growth hormone releasing hormone
US6346264B1 (en) * 1999-04-27 2002-02-12 International Health Products And Services Ltd. Supplement for restoring growth hormone levels
AU772752B2 (en) 1999-07-26 2004-05-06 Baylor College Of Medicine Super-active porcine growth hormone releasing hormone analog
US20040192593A1 (en) * 1999-07-26 2004-09-30 Baylor College Of Medicine Protease resistant ti-growth hormone releasing hormone
UA73530C2 (uk) 1999-11-10 2005-08-15 Ново Нордіск А/С Сполука з властивостями вивільнювати гормон росту
EP1328658A2 (en) * 2000-06-22 2003-07-23 San Diego State University Foundation Recombination modulators and methods for their production and use
EP1411924A1 (en) * 2001-07-06 2004-04-28 Auckland Uniservices Limited Hypertension treatment
CN100417419C (zh) 2001-10-26 2008-09-10 贝勒医学院 改变个体的瘦体重和骨特性的组合物和方法
MY142457A (en) 2001-12-11 2010-11-30 Advisys Inc Plasmid mediated supplementation for treating chronically ill subjects
AR038816A1 (es) * 2002-02-07 2005-01-26 Baylor College Medicine Desarrollo modificado de la glandula pituitaria en la progenie de las hembras prenadas tratadas con terapia con la hormona liberadora de la hormona de crecimiento
CA2513743C (en) * 2003-01-28 2013-06-25 Advisys, Inc. Reducing culling in herd animals growth hormone releasing hormone (ghrh)
ATE533500T1 (de) * 2003-02-14 2011-12-15 Provid Pharmaceuticals Inc Hemmer der antigenpräsentation über mhc-klasse-ii-moleküle und verwendungsverfahren dafür
TW200424214A (en) * 2003-04-21 2004-11-16 Advisys Inc Plasmid mediated GHRH supplementation for renal failures
US7361642B2 (en) * 2003-08-04 2008-04-22 Vgx Pharmaceuticals, Inc. Canine specific growth hormone releasing hormone
EP1711187B1 (en) 2003-12-31 2010-05-12 VGX Pharmaceuticals, LLC Reducing arthritis and lameness in subjects by growth hormone releasing hormone (ghrh) supplementation
ATE507239T1 (de) * 2004-01-20 2011-05-15 VGX Pharmaceuticals LLC Erhöhte sekretion/retention von wachstumshormonfreisetzendem hormon (ghrh) aus muskelzellen durch speziesspezifisches signalpeptid
NZ553274A (en) * 2004-07-23 2010-02-26 VGX Pharmaceuticals LLC Growth hormone releasing hormone enhances the immune response induced by vaccination
US8058253B2 (en) * 2006-07-06 2011-11-15 Vgx Pharmaceuticals, Inc. Growth hormone releasing hormone treatment to decrease cholesterol levels
WO2009073168A1 (en) * 2007-12-03 2009-06-11 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by mhc class ii molecules and methods of use thereof
BRPI0918652B1 (pt) 2008-09-17 2021-10-19 Chiasma, Inc. Composição farmacêutica compreendendo um meio hidrofóbico e uma forma sólida que compreende polipeptídeo e sal de ácido graxo de cadeia média, processo de produção da mesma e forma de dosagem oral
CA2804926C (en) 2010-07-09 2019-01-08 James Trinca Green Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (68)

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US4411890A (en) * 1981-04-14 1983-10-25 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4372884A (en) * 1975-08-06 1983-02-08 The Salk Institute For Biological Studies Pharmaceutically active peptides
US4061626A (en) * 1976-04-29 1977-12-06 Eli Lilly And Company Somatostatin analogs and intermediates thereto
US4105603A (en) * 1977-03-28 1978-08-08 The Salk Institute For Biological Studies Peptides which effect release of hormones
US4127541A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel decapeptides, intermediates therefor, and compositions and methods employing said decapeptides
US4127539A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexacosapeptides, intermediates therefore and pharmaceutical compositions and methods employing said hexacosapeptides
US4127533A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octapeptides, intermediates therefor, and compositions and methods employing said octapeptides
US4127534A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tripeptides, intermediates therefor and pharmaceutical compositions and methods employing said tripeptides
US4127531A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel hexapeptides, intermediates therefor, and compositions and methods employing said hexapeptides
US4127530A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heneicosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said heneicosapeptides
US4127532A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel heptapeptides, intermediates therefor, and compositions and methods employing said heptapeptides
US4127537A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tetracosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said tetracosapeptides
US4127524A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dodecapeptides, intermediates therefor, and compositions and methods employing said dodecapeptides
US4127523A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel undecapeptides, intermediates therefor, and compositions and methods employing said undecapeptides
US4127538A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel pentacosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said pentacosapeptides
US4127525A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tridecapeptides, intermediates therefor, and compositions and methods employing said tridecapeptides
US4127536A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tricosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said tricosapeptides
US4127535A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel dipeptides, intermediates therefor, and compositions and methods employing said dipeptides
US4312857A (en) * 1977-06-16 1982-01-26 The United States Of America As Represented By The Veterans Administration Novel derivatives of beta-endorphin, intermediates therefor and compositions and methods employing said derivatives
US4127522A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel triacontapeptides, intermediates therefor and pharmaceutical compositions and methods employing said triacontapeptides
US4127527A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel pentadecapeptides, intermediates therefor, and compositions and methods employing said pentadecapeptides
US4127519A (en) * 1977-06-16 1978-11-28 Coy David Howard Octadecapeptides, intermediates therefor, and compositions and methods employing said octadecapeptides
US4127517A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel docosapeptides, intermediates therefore and pharmaceutical compositions and methods employing said docosapeptides
US4127529A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel eicosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said eicosapeptides
US4127528A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of alpha-endorphin, intermediates therefor and compositions and methods employing said derivatives
US4127540A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of δ-endorphins, intermediates therefor, and compositions and methods employing said derivatives
US4139504A (en) * 1977-06-16 1979-02-13 Coy David Howard Novel nonapeptides, intermediates therefor, and compositions and methods employing said nonapeptides
US4127518A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel derivatives of gamma-endorphins, intermediates therefor, and compositions and methods employing said derivatives
US4127526A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel tetradecapeptides, intermediates therefor, and compositions and methods employing said tetradecapeptides
US4127520A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel nonadecapeptides, intermediates therefor, and compositions and methods employing said nonadecapeptides
US4127521A (en) * 1977-06-16 1978-11-28 Coy David Howard Novel octacosapeptides, intermediates therefor and pharmaceutical compositions and methods employing said octacosapeptides
US4211693A (en) * 1977-09-20 1980-07-08 The Salk Institute For Biological Studies Peptides with para-substituted phenylalanine
US4178284A (en) * 1978-12-11 1979-12-11 American Home Products Corporation Octapeptides
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
US4228158A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4224316A (en) * 1979-03-30 1980-09-23 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228157A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228155A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223019A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223021A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4226857A (en) * 1979-03-30 1980-10-07 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4228156A (en) * 1979-03-30 1980-10-14 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4223020A (en) * 1979-03-30 1980-09-16 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
NL8005121A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia Biologisch actieve peptiden.
US4316891A (en) * 1980-06-14 1982-02-23 The Salk Institute For Biological Studies Extended N-terminal somatostatin
US4393050A (en) * 1981-04-29 1983-07-12 The Salk Institute For Biological Studies Analogs of extended N-terminal somatostatin
AU549053B2 (en) * 1981-12-28 1986-01-09 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4410513A (en) * 1981-12-28 1983-10-18 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4410512A (en) * 1981-12-28 1983-10-18 Beckman Instruments, Inc. Combinations having synergistic pituitary growth hormone releasing activity
US4428942A (en) * 1982-05-17 1984-01-31 The Salk Institute For Biological Studies Analogs of somatostatin
US4517181A (en) * 1982-09-15 1985-05-14 The Salk Institute For Biological Studies Mammalian PGRF
US4595676A (en) * 1983-04-26 1986-06-17 The Salk Institute For Biological Studies Rat hypothalamic GRF
US4563352A (en) * 1982-10-04 1986-01-07 The Salk Institute For Biological Studies Human pancreatic GRF
US4529595A (en) * 1983-01-13 1985-07-16 The Salk Institute For Biological Studies GRF Analogs
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
US4518586A (en) * 1983-01-13 1985-05-21 The Salk Institute For Biological Studies GRF Analogs III
US4508711A (en) * 1983-04-18 1985-04-02 American Cyanamid Company Cyclic pentapeptide displaying somatostatin antagonism and method of treatment of mammals therewith
US4505897A (en) * 1983-04-18 1985-03-19 The Administrators Of The Tulane Educational Fund Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith
US4628043A (en) * 1983-04-26 1986-12-09 The Salk Institute For Biological Studies Hypothalamic GRF agonists
US4585756A (en) * 1983-10-12 1986-04-29 The Salk Institute For Biological Studies Bovine GRF
US4610976A (en) * 1983-08-29 1986-09-09 The Salk Institute For Biological Studies Porcine GRF
US4605643A (en) * 1984-03-02 1986-08-12 The Salk Institute For Biological Studies Ovine GRF
US4626523A (en) * 1983-09-13 1986-12-02 The Salk Institute For Biological Studies GRF analogs II
US4617149A (en) * 1983-09-21 1986-10-14 Eli Lilly And Company Growth hormone release factor analogs
US4528190A (en) * 1983-10-25 1985-07-09 The Salk Institute For Biological Studies GRF Analogs IV
US4562175A (en) * 1984-02-03 1985-12-31 Ding Chang Synthetic peptides
US4622312A (en) * 1984-09-24 1986-11-11 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
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Also Published As

Publication number Publication date
FI94868C (fi) 1995-11-10
JPH02503798A (ja) 1990-11-08
US4839344A (en) 1989-06-13
NZ225078A (en) 1990-10-26
FI94868B (fi) 1995-07-31
EP0434675A1 (en) 1991-07-03
CA1318463C (en) 1993-05-25
IL86700A0 (en) 1988-11-30
WO1988009780A3 (en) 1989-01-12
AU606736B2 (en) 1991-02-14
WO1988009780A2 (en) 1988-12-15
AU2133688A (en) 1989-01-04
EP0434675B1 (en) 1993-09-01
IE881753L (en) 1988-12-12
FI895905A0 (fi) 1989-12-11
DE3883789D1 (de) 1993-10-07
IE62503B1 (en) 1995-02-08
DE3883789T2 (de) 1994-03-24

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