ME02913B - Čvrsta disperzija - Google Patents

Čvrsta disperzija

Info

Publication number
ME02913B
ME02913B MEP-2017-256A MEP2017256A ME02913B ME 02913 B ME02913 B ME 02913B ME P2017256 A MEP2017256 A ME P2017256A ME 02913 B ME02913 B ME 02913B
Authority
ME
Montenegro
Prior art keywords
solid dispersion
dispersion
solid
Prior art date
Application number
MEP-2017-256A
Other languages
German (de)
English (en)
French (fr)
Inventor
David Shank Fry
Christopher M Lindemann
Michael Preigh
Corey Jay Bloom
Christopher Donovan Craig
Devon Brevard Dubose
Jeff Gautschi
Dan Smithey
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of ME02913B publication Critical patent/ME02913B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Glass Compositions (AREA)
  • Inorganic Insulating Materials (AREA)
  • Optical Communication System (AREA)
MEP-2017-256A 2011-10-14 2012-10-12 Čvrsta disperzija ME02913B (me)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161547620P 2011-10-14 2011-10-14
US201261606207P 2012-03-02 2012-03-02
PCT/US2012/060044 WO2013056108A2 (en) 2011-10-14 2012-10-12 Solid dispersion
EP12809373.9A EP2765990B1 (en) 2011-10-14 2012-10-12 Solid dispersion

Publications (1)

Publication Number Publication Date
ME02913B true ME02913B (me) 2018-04-20

Family

ID=47471981

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2017-256A ME02913B (me) 2011-10-14 2012-10-12 Čvrsta disperzija

Country Status (31)

Country Link
US (5) US9457093B2 (me)
EP (1) EP2765990B1 (me)
JP (2) JP5944514B2 (me)
KR (1) KR102000312B1 (me)
CN (3) CN103998023B (me)
AU (3) AU2012322039C1 (me)
BR (2) BR122020010643B1 (me)
CA (2) CA3114454C (me)
CL (1) CL2014000930A1 (me)
CO (1) CO6960547A2 (me)
CR (1) CR20140228A (me)
CY (1) CY1119837T1 (me)
DK (1) DK2765990T3 (me)
ES (1) ES2650608T3 (me)
HR (1) HRP20171578T1 (me)
HU (1) HUE035247T2 (me)
IL (1) IL232103B (me)
LT (1) LT2765990T (me)
ME (1) ME02913B (me)
MX (1) MX353970B (me)
MY (1) MY169072A (me)
NO (1) NO2021029I1 (me)
PL (1) PL2765990T3 (me)
PT (1) PT2765990T (me)
RS (1) RS56608B1 (me)
RU (1) RU2648448C2 (me)
SG (1) SG11201401459YA (me)
SI (1) SI2765990T1 (me)
TW (3) TWI594769B (me)
WO (1) WO2013056108A2 (me)
ZA (1) ZA201606123B (me)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2765990T3 (da) * 2011-10-14 2017-11-13 Array Biopharma Inc Faststofdispersion
UA116875C2 (uk) 2011-10-14 2018-05-25 Еррей Біофарма Інк. Поліморфи arry-380 селективного інгібітору erbb2 і фармацевтичні композиції, що їх містять
CA2867723C (en) * 2012-03-23 2022-11-08 Array Biopharma Inc. Treatment of brain cancer
AU2014290333B2 (en) * 2013-07-19 2018-11-08 Siga Technologies, Inc. Amorphous Tecovirimat preparation
EP3082803A4 (en) * 2013-12-20 2017-05-31 Phosphorex Inc. Indirubin solid dispersion composition
CA2937315A1 (en) 2014-02-05 2015-08-13 Merck Sharp & Dohme Corp. Tablet formulation for cgrp-active compounds
WO2016198983A1 (en) * 2015-06-09 2016-12-15 Bend Research Inc. Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules
CN107126419B (zh) * 2016-02-26 2020-06-19 石药集团中诺药业(石家庄)有限公司 一种奥贝胆酸片剂及其制备方法
US10828305B2 (en) 2016-03-01 2020-11-10 Shanghai Pharmaceuticals Holding Co., Ltd. Nitrogenous heterocyclic compound, preparation method, intermediate, composition and use
AU2018246258B2 (en) * 2017-03-30 2021-07-29 Merck Patent Gmbh Pharmaceutical formulation
CA3060407A1 (en) 2017-04-28 2018-11-01 Seattle Genetics, Inc. Treatment of her2 positive cancers
TWI780270B (zh) * 2017-11-28 2022-10-11 靜岡縣公立大學法人 固體分散體
KR20200115607A (ko) 2018-01-31 2020-10-07 데시페라 파마슈티칼스, 엘엘씨. 위장관 기질 종양의 치료를 위한 병용 요법
WO2019193488A1 (en) * 2018-04-06 2019-10-10 Capsugel Belgium Nv Spray drying process for low aspect ratio particles comprising poly[(methyl methacrylate)-co-(methacrylic acid)]
CN109942576B (zh) * 2019-03-07 2020-09-11 上海工程技术大学 Irbinitinib及中间体的制备方法
CN111825604A (zh) * 2019-04-16 2020-10-27 宁波药腾医药科技有限公司 一种图卡替尼及其中间产物的合成方法
BR112022002609A2 (pt) 2019-08-12 2022-08-09 Deciphera Pharmaceuticals Llc Métodos de tratamento de tumores estromais gastrointestinais
WO2021030405A1 (en) 2019-08-12 2021-02-18 Deciphera Pharmaceuticals, Llc Ripretinib for treating gastrointestinal stromal tumors
BR112022004376A2 (pt) * 2019-09-19 2022-06-07 Forma Therapeutics Inc Ativação de piruvato quinase r
WO2021080983A1 (en) 2019-10-21 2021-04-29 Seagen Inc. Methods of treating her2 positive breast cancer with tucatinib in combination with capecitabine and trastuzumab
US20220387618A1 (en) 2019-11-15 2022-12-08 Seagen Inc. Methods of treating her2 positive breast cancer with tucatinib in combination with an anti-her2 antibody-drug conjugate
KR20220123058A (ko) 2019-12-30 2022-09-05 데시페라 파마슈티칼스, 엘엘씨. 1-(4-브로모-5-(1-에틸-7-(메틸아미노)-2-옥소-1,2-디히드로-1,6-나프티리딘-3-일)-2-플루오로페닐)-3-페닐우레아의 조성물
KR20220123057A (ko) * 2019-12-30 2022-09-05 데시페라 파마슈티칼스, 엘엘씨. 비정질 키나아제 억제제 제형 및 이의 사용 방법
US20230173067A1 (en) 2020-05-29 2023-06-08 Seagen Inc. Methods of treating her2 positive cancer with tucatinib in combination with trastuzumab and an oxaliplatin-based chemotherapy
AU2021315520A1 (en) 2020-07-29 2023-02-09 Seagen Inc. Methods of treating HER2 positive cancer with tucatinib in combination with trastuzumab, a taxane, and a VEGFR-2 antagonist
CN115340541B (zh) * 2022-07-01 2024-01-30 上海艾洋化学科技有限公司 一种妥卡替尼中间体的制备方法
US11779572B1 (en) 2022-09-02 2023-10-10 Deciphera Pharmaceuticals, Llc Methods of treating gastrointestinal stromal tumors
CN115650977A (zh) * 2022-10-09 2023-01-31 广东润兴生物科技有限公司 一种妥卡替尼的合成方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350786B1 (en) 1998-09-22 2002-02-26 Hoffmann-La Roche Inc. Stable complexes of poorly soluble compounds in ionic polymers
KR20040025881A (ko) * 2000-12-11 2004-03-26 다케다 야쿠힌 고교 가부시키가이샤 개선된 흡수성을 갖는 의약 조성물
PL362979A1 (en) * 2000-12-11 2004-11-02 Takeda Chemical Industries, Ltd. Medicinal compositions improved in solublity in water
US7501427B2 (en) 2003-08-14 2009-03-10 Array Biopharma, Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
EP1660090B1 (en) 2003-08-14 2012-11-21 Array Biopharma, Inc. Quinazoline analogs as receptor tyrosine kinase inhibitors
GB0321648D0 (en) 2003-09-16 2003-10-15 Astrazeneca Ab Quinazoline derivatives
EP1732528A1 (en) * 2004-04-08 2006-12-20 Wyeth Bazedoxifene acetate solid dispersion formulations
KR101086967B1 (ko) * 2005-11-15 2011-11-29 어레이 바이오파마 인크. 과다증식성 질환의 치료를 위한 erbb 유형 i 수용체티로신 키나제 억제제로서의 n4-페닐-퀴나졸린-4-아민유도체 및 관련 화합물
JP5328643B2 (ja) * 2007-04-20 2013-10-30 大同化成工業株式会社 新規乾式固体分散体用基剤、該基剤を含有する固体分散体及び該分散体を含有する組成物
EP2155166A2 (en) 2007-05-11 2010-02-24 F. Hoffmann-Roche AG Pharmaceutical compositions for poorly soluble drugs
EP2205077A4 (en) 2007-09-24 2010-12-29 Tragara Pharmaceuticals Inc THERAPIES FOR THE TREATMENT OF CANCER BASED ON COMBINATIONS OF COX-2 INHIBITORS AND ANTI-HER2 (ERBB2) ANTIBODIES OR COMBINATIONS OF COX-2 INHIBITORS AND HER2 (ERBB2) RECEPTOR TYROSINE KINASE INHIBITORS
ATE551604T1 (de) * 2008-05-05 2012-04-15 Abbott Gmbh & Co Kg Verfahren zur beurteilung der löslichkeit eines kristallinen stoffes in einem polymer
EP2158912A1 (en) * 2008-08-25 2010-03-03 Ratiopharm GmbH Pharmaceutical composition comprising N-[3-chhloro-4-[3-fluorophenyl)methoxy)phenyl]6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine
EP2253306A1 (en) * 2009-05-18 2010-11-24 Royal College of Surgeons in Ireland Orodispersible dosage forms containing solid drug dispersions
DK2765990T3 (da) * 2011-10-14 2017-11-13 Array Biopharma Inc Faststofdispersion
UA116875C2 (uk) 2011-10-14 2018-05-25 Еррей Біофарма Інк. Поліморфи arry-380 селективного інгібітору erbb2 і фармацевтичні композиції, що їх містять
CA2867723C (en) 2012-03-23 2022-11-08 Array Biopharma Inc. Treatment of brain cancer

Also Published As

Publication number Publication date
AU2017210499A1 (en) 2017-08-17
CA3114454C (en) 2022-11-29
AU2019200243B2 (en) 2020-06-11
US20190275043A1 (en) 2019-09-12
AU2017210499C1 (en) 2021-04-29
CN103998023B (zh) 2018-06-15
HUE035247T2 (hu) 2018-05-02
BR122020010643B1 (pt) 2022-05-17
ES2650608T3 (es) 2018-01-19
TW202131902A (zh) 2021-09-01
TW201330876A (zh) 2013-08-01
KR102000312B1 (ko) 2019-07-15
AU2017210499B2 (en) 2019-01-24
WO2013056108A2 (en) 2013-04-18
US20140296267A1 (en) 2014-10-02
US9457093B2 (en) 2016-10-04
US20170136022A1 (en) 2017-05-18
TWI788733B (zh) 2023-01-01
CR20140228A (es) 2014-08-21
CA2852058C (en) 2021-06-01
MX353970B (es) 2018-02-07
PT2765990T (pt) 2017-11-14
RU2014119283A (ru) 2015-11-20
RS56608B1 (sr) 2018-02-28
SI2765990T1 (sl) 2017-11-30
WO2013056108A3 (en) 2013-06-27
CN108498465B (zh) 2022-05-17
CY1119837T1 (el) 2018-06-27
JP5944514B2 (ja) 2016-07-05
NO2021029I1 (no) 2021-07-09
CN108498465A (zh) 2018-09-07
US20210220361A1 (en) 2021-07-22
BR112014009092B1 (pt) 2022-01-18
TW201728323A (zh) 2017-08-16
EP2765990A2 (en) 2014-08-20
AU2012322039A1 (en) 2014-06-05
CA2852058A1 (en) 2013-04-18
CA3114454A1 (en) 2013-04-18
AU2019200243C1 (en) 2021-04-29
US20230097309A1 (en) 2023-03-30
CN114886853A (zh) 2022-08-12
AU2019200243A1 (en) 2019-01-31
IL232103B (en) 2018-11-29
KR20140075798A (ko) 2014-06-19
TWI594769B (zh) 2017-08-11
BR112014009092A2 (pt) 2017-04-18
HRP20171578T1 (hr) 2017-12-01
LT2765990T (lt) 2018-01-25
CL2014000930A1 (es) 2014-07-18
MY169072A (en) 2019-02-12
RU2648448C2 (ru) 2018-03-26
SG11201401459YA (en) 2014-07-30
CN103998023A (zh) 2014-08-20
NZ624942A (en) 2016-06-24
EP2765990B1 (en) 2017-09-06
CO6960547A2 (es) 2014-05-30
TWI722189B (zh) 2021-03-21
AU2012322039B2 (en) 2017-08-17
MX2014004551A (es) 2015-02-12
ZA201606123B (en) 2021-05-26
DK2765990T3 (da) 2017-11-13
IL232103A0 (en) 2014-05-28
AU2012322039C1 (en) 2021-04-29
PL2765990T3 (pl) 2018-01-31
JP2014528484A (ja) 2014-10-27
JP2016027062A (ja) 2016-02-18

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