ME00293B - Sastavi estrogen-ciklodekstrin kompleksa - Google Patents
Sastavi estrogen-ciklodekstrin kompleksaInfo
- Publication number
- ME00293B ME00293B MEP-2008-381A MEP2008381A ME00293B ME 00293 B ME00293 B ME 00293B ME P2008381 A MEP2008381 A ME P2008381A ME 00293 B ME00293 B ME 00293B
- Authority
- ME
- Montenegro
- Prior art keywords
- estrogen
- cyclodextrin
- composition
- compositions
- ethinyl estradiol
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Obezbeđeni su farmaceutski sastavi koji obuhvataju niske doze osetljivih kompleksa između estrogena i ciklodekstrina sa poboljšanom stabilnošću. U specifičnoj realizaciji sastav obuhvata kompleks između etinil estradiola i ?-ciklodekstrin u granulatnom preparatu a u još jednoj realizaciji sastav obuhvata limitiranu količinu polivinilpirolidona pošto je za ovaj inertni punilac pronađeno da degradira etinil estradiol. Dalje, obezbeđen je postupak za poboljšanje stabilnosti estrogena u sastavu i za proizvodnju takvog stabilnog sastava. U osnovi, granulatni preparat je proizveden uz pažljivu kontrolu relativne vlažnosti.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00610135A EP1216713A1 (en) | 2000-12-20 | 2000-12-20 | Compositions of estrogen-cyclodextrin complexes |
PCT/IB2001/002605 WO2002049675A1 (en) | 2000-12-20 | 2001-12-20 | Compositions of estrogen-cyclodextrin complexes |
Publications (1)
Publication Number | Publication Date |
---|---|
ME00293B true ME00293B (me) | 2011-05-10 |
Family
ID=37516219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2008-381A ME00293B (me) | 2000-12-20 | 2001-12-20 | Sastavi estrogen-ciklodekstrin kompleksa |
Country Status (7)
Country | Link |
---|---|
CN (1) | CN101116666B (me) |
AR (1) | AR032205A1 (me) |
ME (1) | ME00293B (me) |
PE (1) | PE20020709A1 (me) |
UA (1) | UA77626C2 (me) |
UY (1) | UY27088A1 (me) |
ZA (1) | ZA200305532B (me) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102512688A (zh) * | 2011-12-29 | 2012-06-27 | 上海新华联制药有限公司 | 尼尔雌醇-β-环糊精包合物及制剂和制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4727064A (en) * | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
NL8801670A (nl) * | 1988-07-01 | 1990-02-01 | Walter Adrianus Josephus Johan | Farmaceutisch preparaat. |
US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
DE19848303A1 (de) * | 1998-10-14 | 2000-04-20 | Schering Ag | Kombination aus Gestagenen und Zuckern |
-
2001
- 2001-12-20 UA UA2003076822A patent/UA77626C2/uk unknown
- 2001-12-20 UY UY27088A patent/UY27088A1/es not_active IP Right Cessation
- 2001-12-20 AR ARP010105936 patent/AR032205A1/es not_active Application Discontinuation
- 2001-12-20 CN CN200610092522.4A patent/CN101116666B/zh not_active Expired - Lifetime
- 2001-12-20 PE PE2001001280A patent/PE20020709A1/es active IP Right Grant
- 2001-12-20 ME MEP-2008-381A patent/ME00293B/me unknown
-
2003
- 2003-07-17 ZA ZA200305532A patent/ZA200305532B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN101116666A (zh) | 2008-02-06 |
ZA200305532B (en) | 2006-06-28 |
PE20020709A1 (es) | 2002-08-23 |
UY27088A1 (es) | 2002-07-31 |
AR032205A1 (es) | 2003-10-29 |
UA77626C2 (en) | 2006-12-15 |
CN101116666B (zh) | 2014-01-08 |
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