MD718Z - Среда для криоконсервации спермы человека - Google Patents
Среда для криоконсервации спермы человека Download PDFInfo
- Publication number
- MD718Z MD718Z MDS20130107A MDS20130107A MD718Z MD 718 Z MD718 Z MD 718Z MD S20130107 A MDS20130107 A MD S20130107A MD S20130107 A MDS20130107 A MD S20130107A MD 718 Z MD718 Z MD 718Z
- Authority
- MD
- Moldova
- Prior art keywords
- medium
- cryopreservation
- sperm
- carnitine
- glucose
- Prior art date
Links
- 238000005138 cryopreservation Methods 0.000 title claims abstract description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 23
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims abstract description 12
- 102000002322 Egg Proteins Human genes 0.000 claims abstract description 11
- 108010000912 Egg Proteins Proteins 0.000 claims abstract description 11
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 11
- 235000013345 egg yolk Nutrition 0.000 claims abstract description 11
- 239000008103 glucose Substances 0.000 claims abstract description 11
- 239000001509 sodium citrate Substances 0.000 claims abstract description 11
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 11
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 10
- 229930006000 Sucrose Natural products 0.000 claims abstract description 10
- 210000002969 egg yolk Anatomy 0.000 claims abstract description 10
- 239000005720 sucrose Substances 0.000 claims abstract description 10
- 239000012154 double-distilled water Substances 0.000 claims description 10
- 235000011187 glycerol Nutrition 0.000 claims description 10
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 4
- 238000010257 thawing Methods 0.000 abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 description 5
- 230000004083 survival effect Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000001850 reproductive effect Effects 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 230000004720 fertilization Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 230000019100 sperm motility Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- RGJOEKWQDUBAIZ-IBOSZNHHSA-N CoASH Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCS)O[C@H]1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 210000000991 chicken egg Anatomy 0.000 description 1
- RGJOEKWQDUBAIZ-UHFFFAOYSA-N coenzime A Natural products OC1C(OP(O)(O)=O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-UHFFFAOYSA-N 0.000 description 1
- 239000005516 coenzyme A Substances 0.000 description 1
- 229940093530 coenzyme a Drugs 0.000 description 1
- 230000000959 cryoprotective effect Effects 0.000 description 1
- 230000000254 damaging effect Effects 0.000 description 1
- KDTSHFARGAKYJN-UHFFFAOYSA-N dephosphocoenzyme A Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 KDTSHFARGAKYJN-UHFFFAOYSA-N 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 239000012456 homogeneous solution Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 210000001700 mitochondrial membrane Anatomy 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Изобретение относится к криобиологии, а именно к среде для криоконсервации спермы человека.Среда для криоконсервации спермы человека содержит, на 100 мл: цитрат натрия 1,1…1,4 г, глюкозу 1,8…3,0 г, сахарозу 6,0…8,4 г, яичный желток 24,0…28,0 мл, глицерин 3,8…4,2 мл, L-карнитин 6,0…10,0 мг и бидистиллированную воду остальное.Результат состоит в повышении физиологических показателей спермы после оттаивания.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130107A MD718Z (ru) | 2013-06-14 | 2013-06-14 | Среда для криоконсервации спермы человека |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130107A MD718Z (ru) | 2013-06-14 | 2013-06-14 | Среда для криоконсервации спермы человека |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD718Y MD718Y (en) | 2014-01-31 |
| MD718Z true MD718Z (ru) | 2014-08-31 |
Family
ID=50071906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20130107A MD718Z (ru) | 2013-06-14 | 2013-06-14 | Среда для криоконсервации спермы человека |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD718Z (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113186101B (zh) * | 2021-04-15 | 2022-10-14 | 上海理工大学 | 一种低温保护剂、制备方法及一种保藏方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1660651A1 (ru) * | 1985-04-18 | 1991-07-07 | Институт проблем криобиологии и криомедицины АН УССР | Способ консервировани спермы человека |
| RU2237712C2 (ru) * | 2002-05-06 | 2004-10-10 | Кострикин Александр Александрович | Среда для криоконсервации клеток человека и животных |
| RU2257710C2 (ru) * | 2003-10-28 | 2005-08-10 | Одинцов Андрей Александрович | Способ криоконсервации спермы человека |
| MD3035G2 (ru) * | 2005-07-18 | 2006-10-31 | Национальный Институт Зоотехнии И Ветеринарии | Среда для разбавления спермы хряков |
| MD58Z (ru) * | 2009-03-13 | 2010-03-31 | Институт Физиологии И Санокреатологии Академии Наук Молдовы | Среда для криоконсервации спермы человека |
| MD201Y (en) * | 2010-02-11 | 2010-05-31 | Institutul De Fiziologie Si Sanocreatologie Al Academiei De Stiinte A Moldovei | Medium for cryoconservation of human sperm |
| EA015422B1 (ru) * | 2006-02-03 | 2011-08-30 | Фапа Витал Анштальт | Комбинированный препарат для улучшения качества сперматозоидов |
-
2013
- 2013-06-14 MD MDS20130107A patent/MD718Z/ru not_active IP Right Cessation
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1660651A1 (ru) * | 1985-04-18 | 1991-07-07 | Институт проблем криобиологии и криомедицины АН УССР | Способ консервировани спермы человека |
| RU2237712C2 (ru) * | 2002-05-06 | 2004-10-10 | Кострикин Александр Александрович | Среда для криоконсервации клеток человека и животных |
| RU2257710C2 (ru) * | 2003-10-28 | 2005-08-10 | Одинцов Андрей Александрович | Способ криоконсервации спермы человека |
| MD3035G2 (ru) * | 2005-07-18 | 2006-10-31 | Национальный Институт Зоотехнии И Ветеринарии | Среда для разбавления спермы хряков |
| EA015422B1 (ru) * | 2006-02-03 | 2011-08-30 | Фапа Витал Анштальт | Комбинированный препарат для улучшения качества сперматозоидов |
| MD58Z (ru) * | 2009-03-13 | 2010-03-31 | Институт Физиологии И Санокреатологии Академии Наук Молдовы | Среда для криоконсервации спермы человека |
| MD201Y (en) * | 2010-02-11 | 2010-05-31 | Institutul De Fiziologie Si Sanocreatologie Al Academiei De Stiinte A Moldovei | Medium for cryoconservation of human sperm |
Non-Patent Citations (1)
| Title |
|---|
| Грищенко В. И., Дунаевская А. В., Калугин Ю. С. Влияние быстрых и сверхбыстрых скоростей замораживания на сохранность спермиев человека. Проблемы криобиологии, 2000, № 2, с. 53. * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD718Y (en) | 2014-01-31 |
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