MD493Z - Metodă de profilaxie a complicaţiilor postradiante în patologiile oncologice - Google Patents
Metodă de profilaxie a complicaţiilor postradiante în patologiile oncologice Download PDFInfo
- Publication number
- MD493Z MD493Z MDS20110121A MDS20110121A MD493Z MD 493 Z MD493 Z MD 493Z MD S20110121 A MDS20110121 A MD S20110121A MD S20110121 A MDS20110121 A MD S20110121A MD 493 Z MD493 Z MD 493Z
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- Moldova
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- radiotherapy
- patients
- complications
- course
- day
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- 230000000771 oncological effect Effects 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title claims description 21
- 238000011321 prophylaxis Methods 0.000 title claims description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title description 3
- 201000010099 disease Diseases 0.000 title 1
- 238000001959 radiotherapy Methods 0.000 claims abstract description 40
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 10
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 9
- 239000002775 capsule Substances 0.000 claims abstract description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000003921 oil Substances 0.000 claims abstract description 6
- 235000019198 oils Nutrition 0.000 claims abstract description 6
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 5
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 4
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 4
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 4
- 239000008169 grapeseed oil Substances 0.000 claims abstract description 4
- 235000012054 meals Nutrition 0.000 claims abstract description 4
- XBCXJKGHPABGSD-UHFFFAOYSA-N methyluracil Natural products CN1C=CC(=O)NC1=O XBCXJKGHPABGSD-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000008171 pumpkin seed oil Substances 0.000 claims abstract description 4
- 229960003471 retinol Drugs 0.000 claims abstract description 4
- 235000020944 retinol Nutrition 0.000 claims abstract description 4
- 239000011607 retinol Substances 0.000 claims abstract description 4
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229930003799 tocopherol Natural products 0.000 claims abstract description 4
- 235000010384 tocopherol Nutrition 0.000 claims abstract description 4
- 229960001295 tocopherol Drugs 0.000 claims abstract description 4
- 239000011732 tocopherol Substances 0.000 claims abstract description 4
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims abstract description 4
- 230000000977 initiatory effect Effects 0.000 claims description 3
- 230000007170 pathology Effects 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 6
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- 230000003439 radiotherapeutic effect Effects 0.000 abstract description 2
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- 206010034811 Pharyngeal cancer Diseases 0.000 description 5
- 210000004877 mucosa Anatomy 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 210000000056 organ Anatomy 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 210000000265 leukocyte Anatomy 0.000 description 3
- 206010065334 Mucosal hyperaemia Diseases 0.000 description 2
- 206010030111 Oedema mucosal Diseases 0.000 description 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 description 2
- 238000009534 blood test Methods 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
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- 206010067484 Adverse reaction Diseases 0.000 description 1
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- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
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- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000009923 canephron Substances 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 201000010536 head and neck cancer Diseases 0.000 description 1
- 208000014829 head and neck neoplasm Diseases 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 210000000777 hematopoietic system Anatomy 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
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- 230000000737 periodic effect Effects 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000004223 radioprotective effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20110121A MD493Z (ro) | 2011-06-29 | 2011-06-29 | Metodă de profilaxie a complicaţiilor postradiante în patologiile oncologice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20110121A MD493Z (ro) | 2011-06-29 | 2011-06-29 | Metodă de profilaxie a complicaţiilor postradiante în patologiile oncologice |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD493Y MD493Y (en) | 2012-03-31 |
| MD493Z true MD493Z (ro) | 2012-10-31 |
Family
ID=45929359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20110121A MD493Z (ro) | 2011-06-29 | 2011-06-29 | Metodă de profilaxie a complicaţiilor postradiante în patologiile oncologice |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD493Z (mo) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD1140C2 (ro) * | 1997-07-15 | 1999-06-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Remediu cu acţiune regenerativă şi citoprotectoare |
| RU2197977C2 (ru) * | 2001-04-17 | 2003-02-10 | Дмитриенко Николай Васильевич | Масло семян тыквы, обладающее противовоспалительным, противоязвенным и гепатопротекторным действием, и способ его получения |
| MD2070G2 (ro) * | 2002-07-12 | 2003-06-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Utilizarea uleiului din seminţe de struguri nerafinat în tratamentul ulcerelor gastrice şi duodenale |
| WO2005089412A2 (en) * | 2004-03-17 | 2005-09-29 | Takemoto Arnold C | Tissue detoxification and health supplements and methods of making and using them |
| MD2933G2 (ro) * | 2005-06-23 | 2006-08-31 | Виктор ГИКАВЫЙ | Metodă de tratament al afecţiunilor ţesutului cutanat |
| EA200601705A1 (ru) * | 2004-03-17 | 2008-04-28 | Арнольд К. Такемото | Детоксикация тканей и оздоровительные добавки, способы их изготовления и применения |
| MD3773G2 (ro) * | 2008-05-30 | 2009-09-30 | Ион МЕРЕУЦЭ | Remediu pentru tratamentul afecţiunilor precanceroase ale tegumentelor şi mucoaselor |
| EA201001000A1 (ru) * | 2010-04-19 | 2011-10-31 | Алмагуль Тулеуовна Маншарипова | Антиоксидантное средство масляный бальзам "ювелакс" |
-
2011
- 2011-06-29 MD MDS20110121A patent/MD493Z/ro not_active IP Right Cessation
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD1140C2 (ro) * | 1997-07-15 | 1999-06-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Remediu cu acţiune regenerativă şi citoprotectoare |
| RU2197977C2 (ru) * | 2001-04-17 | 2003-02-10 | Дмитриенко Николай Васильевич | Масло семян тыквы, обладающее противовоспалительным, противоязвенным и гепатопротекторным действием, и способ его получения |
| MD2070G2 (ro) * | 2002-07-12 | 2003-06-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Utilizarea uleiului din seminţe de struguri nerafinat în tratamentul ulcerelor gastrice şi duodenale |
| WO2005089412A2 (en) * | 2004-03-17 | 2005-09-29 | Takemoto Arnold C | Tissue detoxification and health supplements and methods of making and using them |
| EA200601705A1 (ru) * | 2004-03-17 | 2008-04-28 | Арнольд К. Такемото | Детоксикация тканей и оздоровительные добавки, способы их изготовления и применения |
| MD2933G2 (ro) * | 2005-06-23 | 2006-08-31 | Виктор ГИКАВЫЙ | Metodă de tratament al afecţiunilor ţesutului cutanat |
| MD3773G2 (ro) * | 2008-05-30 | 2009-09-30 | Ион МЕРЕУЦЭ | Remediu pentru tratamentul afecţiunilor precanceroase ale tegumentelor şi mucoaselor |
| EA201001000A1 (ru) * | 2010-04-19 | 2011-10-31 | Алмагуль Тулеуовна Маншарипова | Антиоксидантное средство масляный бальзам "ювелакс" |
Non-Patent Citations (3)
| Title |
|---|
| Каприн А.Д., Семин А.В., Костин А.А. Эффективность препарата "Канефрон Н" у онкологически больных получающих лучевую терапию на органы малого таза. Человек и лекарство, №5, том 15, 2007 * |
| Ролик И.С. Биологические препараты в реабилитации больных раком: руководство для врачей. Москва, Арнебия, 2000 * |
| Справочник Видаль. Лекарственные препараты в России, издание 15-е, 2009 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD493Y (en) | 2012-03-31 |
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| Date | Code | Title | Description |
|---|---|---|---|
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |