MD4845C1 - Способ получения активного комплекса из личинок Lymantria dispar - Google Patents
Способ получения активного комплекса из личинок Lymantria dispar Download PDFInfo
- Publication number
- MD4845C1 MD4845C1 MDA20220008A MD20220008A MD4845C1 MD 4845 C1 MD4845 C1 MD 4845C1 MD A20220008 A MDA20220008 A MD A20220008A MD 20220008 A MD20220008 A MD 20220008A MD 4845 C1 MD4845 C1 MD 4845C1
- Authority
- MD
- Moldova
- Prior art keywords
- larvae
- active complex
- biomass
- obtaining
- temperature
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 36
- 241000721703 Lymantria dispar Species 0.000 title claims abstract description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 15
- 235000013312 flour Nutrition 0.000 claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 238000004108 freeze drying Methods 0.000 claims abstract description 7
- 238000007710 freezing Methods 0.000 claims abstract description 6
- 230000008014 freezing Effects 0.000 claims abstract description 6
- 241000209140 Triticum Species 0.000 claims abstract description 5
- 235000021307 Triticum Nutrition 0.000 claims abstract description 5
- 235000012907 honey Nutrition 0.000 claims abstract description 5
- 238000004806 packaging method and process Methods 0.000 claims abstract description 5
- 239000008213 purified water Substances 0.000 claims abstract description 5
- 235000013311 vegetables Nutrition 0.000 claims abstract description 5
- 238000005406 washing Methods 0.000 claims abstract description 5
- RTIXKCRFFJGDFG-UHFFFAOYSA-N Chrysin Natural products C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 RTIXKCRFFJGDFG-UHFFFAOYSA-N 0.000 claims abstract description 4
- FGUBFGWYEYFGRK-HNNXBMFYSA-N Pinocembrin Natural products Cc1cc(C)c2C(=O)C[C@H](Oc2c1)c3ccccc3 FGUBFGWYEYFGRK-HNNXBMFYSA-N 0.000 claims abstract description 4
- 240000008042 Zea mays Species 0.000 claims abstract description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 4
- 235000005822 corn Nutrition 0.000 claims abstract description 4
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 claims abstract description 4
- SUYJZKRQHBQNCA-LSDHHAIUSA-N pinobanksin Chemical compound C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)O)=CC=CC=C1 SUYJZKRQHBQNCA-LSDHHAIUSA-N 0.000 claims abstract description 4
- SUYJZKRQHBQNCA-UHFFFAOYSA-N pinobanksin Natural products O1C2=CC(O)=CC(O)=C2C(=O)C(O)C1C1=CC=CC=C1 SUYJZKRQHBQNCA-UHFFFAOYSA-N 0.000 claims abstract description 4
- URFCJEUYXNAHFI-ZDUSSCGKSA-N pinocembrin Chemical compound C1([C@@H]2CC(=O)C3=C(O)C=C(C=C3O2)O)=CC=CC=C1 URFCJEUYXNAHFI-ZDUSSCGKSA-N 0.000 claims abstract description 4
- 235000020183 skimmed milk Nutrition 0.000 claims abstract description 4
- YZYKBQUWMPUVEN-UHFFFAOYSA-N zafuleptine Chemical compound OC(=O)CCCCCC(C(C)C)NCC1=CC=C(F)C=C1 YZYKBQUWMPUVEN-UHFFFAOYSA-N 0.000 claims abstract description 3
- 235000012054 meals Nutrition 0.000 claims description 2
- 239000002028 Biomass Substances 0.000 abstract description 29
- 238000002360 preparation method Methods 0.000 abstract description 11
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 7
- 230000004071 biological effect Effects 0.000 abstract description 7
- 239000011701 zinc Substances 0.000 abstract description 7
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 6
- 229910052725 zinc Inorganic materials 0.000 abstract description 6
- 150000001413 amino acids Chemical class 0.000 abstract description 5
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract description 3
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract description 3
- 241000721696 Lymantria Species 0.000 abstract description 2
- 208000013507 chronic prostatitis Diseases 0.000 abstract description 2
- 201000007094 prostatitis Diseases 0.000 abstract description 2
- 239000000284 extract Substances 0.000 description 14
- 239000000203 mixture Substances 0.000 description 8
- 241000238631 Hexapoda Species 0.000 description 7
- 230000003078 antioxidant effect Effects 0.000 description 7
- 238000000605 extraction Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 235000013601 eggs Nutrition 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 230000000975 bioactive effect Effects 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 229940099259 vaseline Drugs 0.000 description 4
- 102000004890 Interleukin-8 Human genes 0.000 description 3
- 108090001007 Interleukin-8 Proteins 0.000 description 3
- 239000013543 active substance Substances 0.000 description 3
- 239000012620 biological material Substances 0.000 description 3
- 238000009395 breeding Methods 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 239000000829 suppository Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000219492 Quercus Species 0.000 description 2
- 241000254109 Tenebrio molitor Species 0.000 description 2
- 230000002225 anti-radical effect Effects 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 239000006286 aqueous extract Substances 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000003797 essential amino acid Substances 0.000 description 2
- 230000012447 hatching Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 230000001418 larval effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 229940127557 pharmaceutical product Drugs 0.000 description 2
- 208000017497 prostate disease Diseases 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 238000007738 vacuum evaporation Methods 0.000 description 2
- 238000003828 vacuum filtration Methods 0.000 description 2
- OADSZWXMXIWZSQ-UHFFFAOYSA-N 2-bromo-2-nitropropane Chemical compound CC(C)(Br)[N+]([O-])=O OADSZWXMXIWZSQ-UHFFFAOYSA-N 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 241000255777 Lepidoptera Species 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 102000004895 Lipoproteins Human genes 0.000 description 1
- 108090001030 Lipoproteins Proteins 0.000 description 1
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 1
- 241000219000 Populus Species 0.000 description 1
- 206010036940 Prostatic adenoma Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 240000006394 Sorghum bicolor Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- GLEVLJDDWXEYCO-UHFFFAOYSA-N Trolox Chemical compound O1C(C)(C(O)=O)CCC2=C1C(C)=C(C)C(O)=C2C GLEVLJDDWXEYCO-UHFFFAOYSA-N 0.000 description 1
- 206010046798 Uterine leiomyoma Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940088623 biologically active substance Drugs 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- FBQVFXLUGAFMIO-UHFFFAOYSA-N hexadecyl 16-methylheptadecanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC(C)C FBQVFXLUGAFMIO-UHFFFAOYSA-N 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 description 1
- 229940096397 interleukin-8 Drugs 0.000 description 1
- 229940070765 laurate Drugs 0.000 description 1
- 201000010260 leiomyoma Diseases 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 230000003859 lipid peroxidation Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000012792 lyophilization process Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000006215 rectal suppository Substances 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 239000004246 zinc acetate Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/30—Rearing or breeding invertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/30—Rearing or breeding invertebrates
- A01K67/34—Insects
- A01K67/35—Silkworms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/90—Feeding-stuffs specially adapted for particular animals for insects, e.g. bees or silkworms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Environmental Sciences (AREA)
- Insects & Arthropods (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Birds (AREA)
- Rheumatology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Feed For Specific Animals (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Изобретение относится к области фармацевтики, а именно к способам получения препаратов с противовоспалительным действием, предназначенных для лечения доброкачественной гиперплазии предстательной железы, связанной или не связанной с хроническим простатитом.Способ получения активного комплекса из личинок Lymantria dispar, согласно изобретению, включает выращивание насекомых Lymantria dispar до 4-го возраста в контролируемых условиях на стандартизированной среде, содержащей, г/кг: пшеничную муку 80-95, кукурузную муку 82-87, сухую растительную массу 110-120, сухое обезжиренное молоко 2,5-3,5, пчелиный мед 17-19, глицерин 10-12, пинобанксин 0,01-0,02, пиноцембрин 0,01-0,02, ацетат цинка двуводный 0,03-0,05, очищенную воду остальное, замораживание личинок при температуре -18°С, промывание личинок, первичное измельчение, лиофилизацию, измельчение при температуре -55°С, упаковку и хранение активного комплекса при температуре -18°С.Технический результат изобретения состоит в повышении количества биомассы с более высокой биологической активностью и содержания цинка и протеиногенных аминокислот, в том числе незаменимых.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20220008A MD4845C1 (ru) | 2022-02-07 | 2022-02-07 | Способ получения активного комплекса из личинок Lymantria dispar |
| PCT/MD2023/000001 WO2023149794A1 (ru) | 2022-02-07 | 2023-01-24 | Способ получения активного комплекса из личинок lymantria dispar |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20220008A MD4845C1 (ru) | 2022-02-07 | 2022-02-07 | Способ получения активного комплекса из личинок Lymantria dispar |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD4845B1 MD4845B1 (ru) | 2023-02-28 |
| MD4845C1 true MD4845C1 (ru) | 2024-05-31 |
Family
ID=85383304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20220008A MD4845C1 (ru) | 2022-02-07 | 2022-02-07 | Способ получения активного комплекса из личинок Lymantria dispar |
Country Status (2)
| Country | Link |
|---|---|
| MD (1) | MD4845C1 (ru) |
| WO (1) | WO2023149794A1 (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4713C1 (ru) * | 2018-07-19 | 2021-04-30 | Чеслав ЧУХРИЙ | Способ получения активного комплекса из личинок Lymantria dispar |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD4713C1 (ru) * | 2018-07-19 | 2021-04-30 | Чеслав ЧУХРИЙ | Способ получения активного комплекса из личинок Lymantria dispar |
-
2022
- 2022-02-07 MD MDA20220008A patent/MD4845C1/ru active IP Right Grant
-
2023
- 2023-01-24 WO PCT/MD2023/000001 patent/WO2023149794A1/ru not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023149794A1 (ru) | 2023-08-10 |
| MD4845B1 (ru) | 2023-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Kieliszek et al. | Recent advances and opportunities related to the use of bee products in food processing | |
| KR20110043657A (ko) | 틸라코이드를 제조하기 위한 대규모 방법 | |
| KR20090098732A (ko) | 항염증, 항산화 또는 항세균 조성물 | |
| CN106106549A (zh) | 一种高效苹果树伤口愈合剂 | |
| KR20080079743A (ko) | 아토피성 피부염 치료효과를 갖는 산야초를 이용한발효물의 제조방법 | |
| RU2063151C1 (ru) | Способ получения пищевой добавки из корня женьшеня | |
| MD4845C1 (ru) | Способ получения активного комплекса из личинок Lymantria dispar | |
| Ecem-Bayram et al. | Appropriate maceration duration for the extraction of propolis | |
| CN106309629A (zh) | 一种草本精华提取物及其制备方法 | |
| MD4713C1 (ru) | Способ получения активного комплекса из личинок Lymantria dispar | |
| KR101940926B1 (ko) | 죽염을 이용한 천연비누 및 이의 제조방법 | |
| Omorodion et al. | Antimicrobial activities of aqueous and ethanolic extracts of some natural spices (garlic, turmeric, thyme and onions) on some clinical isolates | |
| Deshmukh et al. | Utilization of Aloe vera (L) herbal tonic for treating mulberry leaves before feeding the fifth instar larvae of silkworm, Bombyx mori L.(Race: PM× CSR2) | |
| KR102128411B1 (ko) | 산양삼 숙성액 및 이의 제조방법 | |
| TW200948371A (en) | Cultivation method and liquid culture medium for cultivation of mycelium and fruiting body of Cordyceps | |
| Vinayaka et al. | Ethnic Knowledge on Medicinal and Nutritional Attributes of Lichens with Emphasis on the Western Ghats | |
| JP2011231068A (ja) | Ｎｋ活性増強剤 | |
| KR101713115B1 (ko) | 발효 오신채 추출물을 함유하는 화장료 조성물 | |
| CN100506283C (zh) | 植物基质 | |
| KR20210013501A (ko) | 피부 보호효과를 갖는 비파나무 잎 미네랄당 숙성액 및 이의 제조 방법 | |
| CN107372477A (zh) | 一种用于玫瑰切花保鲜的农用药品组合物 | |
| CN108887320A (zh) | 一种萱草花蛋糕预拌粉及其制备方法 | |
| KR101586053B1 (ko) | 꾸찌뽕 분말화 제조방법 | |
| WO2022111551A1 (zh) | 红肉苹果和樱桃李组合物及其在降血脂方面的应用 | |
| KR100946690B1 (ko) | 유기농 토마토, 매실, 진피, 복숭아 및 알로에의 발효추출물을 함유하는 항염 효과를 갖는 화장료 조성물 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued |