MD4178C1 - Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului - Google Patents

Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului Download PDF

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Publication number
MD4178C1
MD4178C1 MDA20120023A MD20120023A MD4178C1 MD 4178 C1 MD4178 C1 MD 4178C1 MD A20120023 A MDA20120023 A MD A20120023A MD 20120023 A MD20120023 A MD 20120023A MD 4178 C1 MD4178 C1 MD 4178C1
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MD
Moldova
Prior art keywords
diphenylimidazole
nitro
producing
compounds
coordinative
Prior art date
Application number
MDA20120023A
Other languages
English (en)
Romanian (ro)
Russian (ru)
Other versions
MD4178B1 (en
Inventor
Константин ИНДРИЧАН
Ирина ВОДЭ
Вадим ДРУЦЭ
Константин ТУРТЭ
Original Assignee
Институт Химии Академии Наук Молдовы
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Publication date
Application filed by Институт Химии Академии Наук Молдовы filed Critical Институт Химии Академии Наук Молдовы
Priority to MDA20120023A priority Critical patent/MD4178C1/ro
Publication of MD4178B1 publication Critical patent/MD4178B1/mo
Publication of MD4178C1 publication Critical patent/MD4178C1/ro

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MDA20120023A 2012-02-27 2012-02-27 Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului MD4178C1 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20120023A MD4178C1 (ro) 2012-02-27 2012-02-27 Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20120023A MD4178C1 (ro) 2012-02-27 2012-02-27 Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului

Publications (2)

Publication Number Publication Date
MD4178B1 MD4178B1 (en) 2012-07-31
MD4178C1 true MD4178C1 (ro) 2013-02-28

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MDA20120023A MD4178C1 (ro) 2012-02-27 2012-02-27 Procedeu de obţinere a 2-nitro-4,5-difenilimidazolului

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MD (1) MD4178C1 (mo)

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB700211A (en) * 1950-07-21 1953-11-25 Ciba Ltd Manufacture of azo dyestuffs
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
US4241060A (en) * 1977-08-19 1980-12-23 Hoffmann-La Roche Inc. Nitroimidazoles and compositions thereof
US5008398A (en) * 1988-10-15 1991-04-16 Basf Aktiengesellschaft Preparation of p-nitrophenyl-imidazoles
EP0510036A1 (en) * 1990-01-12 1992-10-28 Rhone Poulenc Rorer Sa 2-SUBSTITUTED 4,5-DIPHENYLIMIDAZOLES.
WO1994019310A1 (en) * 1993-02-26 1994-09-01 Instituto Nacional De Engenharia E Tecnologia Industrial New process for the nitration of aromatic compounds in mild, non-corrosive conditions
RU2021249C1 (ru) * 1990-10-16 1994-10-15 Индивидуально-частное предприятие "Ост-Вест" Способ получения ароматических 1,2-дикетонов
CN1736976A (zh) * 2005-08-30 2006-02-22 南京大学 硝酸铝在芳环硝化中的应用
WO2008070336A2 (en) * 2006-10-27 2008-06-12 Natural Pharmacia International, Inc. Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof
US20100004460A1 (en) * 2007-01-23 2010-01-07 Pola Pharma Inc Method for producing 2-nitroimidazole derivative
MD4150B1 (en) * 2011-10-11 2012-02-29 Inst De Chimie Al Academiei De Stiinte A Moldovei Process for producing coordinative compounds of Co(II), Ni(II) and Zn(II) with 2-nitro-4,5-diphenylimidazole starting from 4,5-diphenylimidazole and nitrates of said metals

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB700211A (en) * 1950-07-21 1953-11-25 Ciba Ltd Manufacture of azo dyestuffs
US4241060A (en) * 1977-08-19 1980-12-23 Hoffmann-La Roche Inc. Nitroimidazoles and compositions thereof
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
US5008398A (en) * 1988-10-15 1991-04-16 Basf Aktiengesellschaft Preparation of p-nitrophenyl-imidazoles
EP0510036A1 (en) * 1990-01-12 1992-10-28 Rhone Poulenc Rorer Sa 2-SUBSTITUTED 4,5-DIPHENYLIMIDAZOLES.
RU2021249C1 (ru) * 1990-10-16 1994-10-15 Индивидуально-частное предприятие "Ост-Вест" Способ получения ароматических 1,2-дикетонов
WO1994019310A1 (en) * 1993-02-26 1994-09-01 Instituto Nacional De Engenharia E Tecnologia Industrial New process for the nitration of aromatic compounds in mild, non-corrosive conditions
CN1736976A (zh) * 2005-08-30 2006-02-22 南京大学 硝酸铝在芳环硝化中的应用
WO2008070336A2 (en) * 2006-10-27 2008-06-12 Natural Pharmacia International, Inc. Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof
US7842278B2 (en) * 2006-10-27 2010-11-30 Natural Pharmacia International, Inc. Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof
US20100004460A1 (en) * 2007-01-23 2010-01-07 Pola Pharma Inc Method for producing 2-nitroimidazole derivative
MD4150B1 (en) * 2011-10-11 2012-02-29 Inst De Chimie Al Academiei De Stiinte A Moldovei Process for producing coordinative compounds of Co(II), Ni(II) and Zn(II) with 2-nitro-4,5-diphenylimidazole starting from 4,5-diphenylimidazole and nitrates of said metals

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
Bergan T. Antibacterial activity and pharmacokinetics of nitroimidazoles. A review. Scand. J. Infect. Dis., 1985, vol. 17 (Suppl. 46), p. 64-71 *
Charlson R.H., Brown T.L. Inorg. Chem., vol. 5, no. 2, 1966, p. 268 *
Cornelius A., Laszlo P., "Clay supported copper(II) and iron(III) nitrates: novel multipurpose reagents for organic synthesis". Synthesis, October, p. 909-918 (1985) *
Es T. van and Backerberg O.G. Substitution of 4,5-diphenyl-oxazoles and some related compounds. J. Chem. Soc., 1963, p. 1363-1370 *
Palamaru M.N., Iordan A.R., Cecal A. Chimie bioanorganică şi metalele vieţii, BIT, Iaşi, 1997, 395 p. *
Sathururu R and Biehl Ed, "Facile, high-yield, regioselective synthesis of ortho-nitroderivatives of hydroxy heterocycles using cerium (IV) ammonium nitrate", ARCHIVOC, The Archive for Organic Chemistry, 2004 (xiv) 89-95. Published on the web 23 Sep 2004, (regăsit în Internet la 2011.12.20, url: http://quod.lib.umich.edu/cgi/p/pod/dod-idx?c=ark;idno=5550190.0005.e09 ) *
Yagovkin A.Yu. and Bakibaev A.A. Formation of a 2-Nitro Derivative in the Oxidation of 4,5-Diphenylimidazole to Benzyl using Nitric Acid. Chemistry of Heterocyclic Compounds, 1995, vol.31, No. 12, p. 1696-1697 *
Новиков С.С. и др. Химия Гетероциклических Соединений, 1970, № 4, с. 503 *
Эйхгорн Г. Неорганическая химия, Мир, Москва, 1978, том 1, том 2 *

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