MD4178B1 - Process for producing 2-nitro-4,5-diphenylimidazole - Google Patents

Process for producing 2-nitro-4,5-diphenylimidazole

Info

Publication number
MD4178B1
MD4178B1 MDA20120023A MD20120023A MD4178B1 MD 4178 B1 MD4178 B1 MD 4178B1 MD A20120023 A MDA20120023 A MD A20120023A MD 20120023 A MD20120023 A MD 20120023A MD 4178 B1 MD4178 B1 MD 4178B1
Authority
MD
Moldova
Prior art keywords
diphenylimidazole
nitro
producing
compounds
coordinative
Prior art date
Application number
MDA20120023A
Other languages
Moldavian (mo)
Romanian (ro)
Other versions
MD4178C1 (en
Inventor
Constantin Indricean
Irina Voda
Vadim Drutseh
Constantin Turta
Irina Vodă
Vadim Druţă
Constantin Turtă
Original Assignee
Inst De Chimie Al Academiei De Stiinte A Moldovei
Inst De Chimie Al Academiei De & Scedil Tiin & Tcedil E A Moldovei
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst De Chimie Al Academiei De Stiinte A Moldovei, Inst De Chimie Al Academiei De & Scedil Tiin & Tcedil E A Moldovei filed Critical Inst De Chimie Al Academiei De Stiinte A Moldovei
Priority to MDA20120023A priority Critical patent/MD4178C1/en
Publication of MD4178B1 publication Critical patent/MD4178B1/en
Publication of MD4178C1 publication Critical patent/MD4178C1/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to the field of chemistry, in particular to derivatives of 2-nitro-4,5-diarylimidazole that can be used as biologically active compounds, catalysts, etc.Summary of the invention consists in that it is proposed a process for producing 2-nitro-4,5-diphenylimidazole by the reaction of demetalation with a mineral acid at pH≤ 2 in aqueous medium of coordinative compounds of Co(II), Ni(II) and Zn(II) with 2-nitro-4,5-diphenylimidazole. After neutralization of the resulting mixture the target compound is extracted with a water-immiscible solvent and is isolated from the extract.The initial coordinative compounds can be obtained at the interaction of 4,5-diphenylimidazole with the nitrate of the corresponding metal in solvothermal conditions with in situnitration of heterocycle.
MDA20120023A 2012-02-27 2012-02-27 Process for producing 2-nitro-4,5-diphenylimidazole MD4178C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20120023A MD4178C1 (en) 2012-02-27 2012-02-27 Process for producing 2-nitro-4,5-diphenylimidazole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20120023A MD4178C1 (en) 2012-02-27 2012-02-27 Process for producing 2-nitro-4,5-diphenylimidazole

Publications (2)

Publication Number Publication Date
MD4178B1 true MD4178B1 (en) 2012-07-31
MD4178C1 MD4178C1 (en) 2013-02-28

Family

ID=46582440

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20120023A MD4178C1 (en) 2012-02-27 2012-02-27 Process for producing 2-nitro-4,5-diphenylimidazole

Country Status (1)

Country Link
MD (1) MD4178C1 (en)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB700211A (en) * 1950-07-21 1953-11-25 Ciba Ltd Manufacture of azo dyestuffs
IE47132B1 (en) * 1977-08-19 1983-12-28 Roche Products Ltd Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
DE3835195A1 (en) * 1988-10-15 1990-04-19 Basf Ag METHOD FOR PRODUCING P-NITROPHENYL IMIDAZOLES
WO1991010662A1 (en) * 1990-01-12 1991-07-25 Rhone-Poulenc Rorer S.A. 2-substituted 4,5-diphenyl-imidazoles
RU2021249C1 (en) * 1990-10-16 1994-10-15 Индивидуально-частное предприятие "Ост-Вест" Method of synthesis of aromatic 1,2-diketones
PT101207A (en) * 1993-02-26 1994-08-31 Inst Nac De Engenharia E Tecno PROCESS FOR THE NITRACAO OF AROMATIC COMPOUNDS IN SOFT AND NON-CORROSIVE CONDITIONS
CN1736976A (en) * 2005-08-30 2006-02-22 南京大学 Use of aluminum nitrate in aromatic ring nitration
US7842278B2 (en) * 2006-10-27 2010-11-30 Natural Pharmacia International, Inc. Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof
EP2128140B1 (en) * 2007-01-23 2012-03-14 Pola Pharma Inc. Method for producing 2-nitroimidazole derivative
MD4150C1 (en) * 2011-10-11 2012-09-30 Институт Химии Академии Наук Молдовы Process for producing coordinative compounds of Co(II), Ni(II) and Zn(II) with 2-nitro-4,5-diphenylimidazole starting from 4,5-diphenylimidazole and nitrates of said metals

Also Published As

Publication number Publication date
MD4178C1 (en) 2013-02-28

Similar Documents

Publication Publication Date Title
MX340125B (en) Storage-stable 2-hydroxy-4-(methylthio) butyric acid nitrile.
MX2023005703A (en) Method for producing novel nitrogen-containing compound or salt thereof, and production intermediate of same.
BR112018005284A2 (en) Crosslinked type nucleic acid GuNA, its manufacturing method, and an intermediate compound
MX348977B (en) Preparation of bicyclic guanidine salts in an aqueous media.
WO2012061460A3 (en) Method for producing ammonium sulfate nitrate
IN2014CN02188A (en)
MX2017015606A (en) Process for preparing 3-methylcyclopentadecane-1,5-dione.
MX2015016371A (en) Methods and compositions for templated assembly of nucleic acid specific heterocompounds.
MX362188B (en) Process for the preparation of xanthohumol.
WO2014210416A8 (en) Helicase suppression of non-template amplification
PH12016500913A1 (en) Soap bar
PH12018500677A1 (en) Method for producing optically active 2- (2-fluorobiphenyl-4-yl) propanoic acid
BR112016006865A2 (en) substituted berberines and their syntheses
MY172332A (en) Method for revamping a self-stripping urea plant
MX2018000196A (en) Process for the preparation of a furfural derivative.
MX350430B (en) Process for preparing 4-amino-5-biphenyl-4-yl-2-hydroxymethyl-2-m ethyl-pentanoic acid compounds.
SG10201810692VA (en) Process to prepare 3-methyl-2-nitrobenzoic acid by air oxidation
PH12014501704A1 (en) Method for preparing compound by novel michael addition reaction using water or various acids as additive
SG10201901578UA (en) Processes for the preparation of pyrimidinylcyclopentane compounds
MY182164A (en) Process for producing acetic acid by introducing a lithium compound
MD4178B1 (en) Process for producing 2-nitro-4,5-diphenylimidazole
IN2015DN02241A (en)
GB2519486A (en) A method for preparing oxycodone
WO2011110198A8 (en) A process for making voriconazole
MX2018010406A (en) Method for producing sulfoxide derivative.

Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees