IN2015DN02241A - - Google Patents

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Publication number
IN2015DN02241A
IN2015DN02241A IN2241DEN2015A IN2015DN02241A IN 2015DN02241 A IN2015DN02241 A IN 2015DN02241A IN 2241DEN2015 A IN2241DEN2015 A IN 2241DEN2015A IN 2015DN02241 A IN2015DN02241 A IN 2015DN02241A
Authority
IN
India
Prior art keywords
compound
salt
angiotensin
general formula
receptor antagonist
Prior art date
Application number
Inventor
Corporation Api
Original Assignee
Api Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Api Corp filed Critical Api Corp
Publication of IN2015DN02241A publication Critical patent/IN2015DN02241A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/54—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
    • B01J23/56—Platinum group metals
    • B01J23/58—Platinum group metals with alkali- or alkaline earth metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Abstract

Provided is a novel production method for an angiotensin II receptor antagonist which is related to a deprotection method for a tetrazole compound performed under conditions that are economical and suitable for industrial production said tetrazole compound being useful as an intermediate for the angiotensin II receptor antagonist. A method for producing a compound that is represented by general formula (3) or (4) or a salt thereof said method being characterized in that a compound represented by general formula (1) or (2) or a salt thereof is (i) reduced in the presence of a metal catalyst and an alkaline earth metal salt or (ii) reacted with a specific amount of a Brfnsted acid. (In the formulae the symbols are as defined in the description.)
IN2241DEN2015 2012-09-26 2013-09-26 IN2015DN02241A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012213212 2012-09-26
PCT/JP2013/076152 WO2014051008A1 (en) 2012-09-26 2013-09-26 Deprotection method for tetrazole compound

Publications (1)

Publication Number Publication Date
IN2015DN02241A true IN2015DN02241A (en) 2015-08-21

Family

ID=50388403

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2241DEN2015 IN2015DN02241A (en) 2012-09-26 2013-09-26

Country Status (6)

Country Link
US (1) US9527821B2 (en)
EP (1) EP2902385B1 (en)
JP (1) JP5881837B2 (en)
CN (1) CN104662008B (en)
IN (1) IN2015DN02241A (en)
WO (1) WO2014051008A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104583185A (en) 2012-08-31 2015-04-29 株式会社Api Method for producing biaryl compound
CN105418593A (en) * 2015-11-25 2016-03-23 蚌埠丰原涂山制药有限公司 Preparation method of key intermediate of olmesartan medoxomil and olmesartan medoxomil
CN105481842A (en) * 2015-12-15 2016-04-13 江苏中邦制药有限公司 Method for preparing olmesartan medoxomil

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI112942B3 (en) 1991-02-21 2012-03-13 Daiichi Sankyo Co Ltd Process for the preparation of 4 '- (1H-imidazol-1-ylmethyl) -1,1'-biphenyl derivatives useful for the treatment and prevention of hypertension
JPH10195063A (en) * 1996-10-21 1998-07-28 Dai Ichi Seiyaku Co Ltd Ethynylthiazole derivative
KR20020069510A (en) * 1999-10-28 2002-09-04 에쎈셜 쎄라퓨틱스, 인크. Drug discharge pump inhibitors
JP2002322054A (en) * 2001-04-26 2002-11-08 Dai Ichi Seiyaku Co Ltd Drug discharging pump inhibitor
CN1271068C (en) 2003-03-25 2006-08-23 上海医药工业研究院 Novel method for preparing olmesartan
ITMI20032267A1 (en) 2003-11-21 2005-05-22 Dinamite Dipharma S P A In Forma A Bbreviata Diph PROCDIMENTO FOR PREPARATION OF VALSARTAN AND ITS INTERMEDIATES
EP2074116A2 (en) 2006-10-09 2009-07-01 Cipla Limited Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil
US7830311B2 (en) 2007-07-18 2010-11-09 Murata Manufacturing Co., Ltd. Wireless IC device and electronic device
EP2217580B1 (en) 2007-10-12 2011-12-21 ArQule, Inc. Substituted tetrazole compounds and uses thereof
EP2502919A4 (en) 2009-11-17 2013-06-26 Mitsubishi Tanabe Pharma Corp Process for production of biphenyl derivative
CN104583185A (en) * 2012-08-31 2015-04-29 株式会社Api Method for producing biaryl compound

Also Published As

Publication number Publication date
CN104662008B (en) 2017-03-08
WO2014051008A1 (en) 2014-04-03
EP2902385A4 (en) 2016-03-09
JP5881837B2 (en) 2016-03-09
JPWO2014051008A1 (en) 2016-08-22
US20150239854A1 (en) 2015-08-27
US9527821B2 (en) 2016-12-27
EP2902385B1 (en) 2019-01-09
EP2902385A1 (en) 2015-08-05
CN104662008A (en) 2015-05-27

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