MD4014B1 - Polyoxometalate complexes with antitumor activity - Google Patents

Polyoxometalate complexes with antitumor activity

Info

Publication number
MD4014B1
MD4014B1 MDA20090046A MD20090046A MD4014B1 MD 4014 B1 MD4014 B1 MD 4014B1 MD A20090046 A MDA20090046 A MD A20090046A MD 20090046 A MD20090046 A MD 20090046A MD 4014 B1 MD4014 B1 MD 4014B1
Authority
MD
Moldova
Prior art keywords
antitumor activity
synthesis
complex compounds
polyoxometalate
polyoxometalate complex
Prior art date
Application number
MDA20090046A
Other languages
Romanian (ro)
Other versions
MD4014C2 (en
Inventor
Tatiana Gutul
Anatolii Dimoglo
Maxim SOKOLOV
Seval Korkmaz
Original Assignee
Tatiana Gutul
Anatolii Dimoglo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tatiana Gutul, Anatolii Dimoglo filed Critical Tatiana Gutul
Priority to MDA20090046A priority Critical patent/MD4014C2/en
Publication of MD4014B1 publication Critical patent/MD4014B1/en
Publication of MD4014C2 publication Critical patent/MD4014C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the synthesis of polyoxometalate complex compounds possessing antitumor activity.Summary of the invention consists in the synthesis of polyoxometalate complex compounds of formula:where selenium atoms (IV) are central. The result of the invention consists in the synthesis of polyoxometalate complex compounds possesing 85à92% inhibiting effect of the tumor cells at a concentration of 10à100 MyM.
MDA20090046A 2009-04-23 2009-04-23 Polyoxometalate complexes with antitumor activity MD4014C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20090046A MD4014C2 (en) 2009-04-23 2009-04-23 Polyoxometalate complexes with antitumor activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20090046A MD4014C2 (en) 2009-04-23 2009-04-23 Polyoxometalate complexes with antitumor activity

Publications (2)

Publication Number Publication Date
MD4014B1 true MD4014B1 (en) 2010-02-26
MD4014C2 MD4014C2 (en) 2010-09-30

Family

ID=43568899

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20090046A MD4014C2 (en) 2009-04-23 2009-04-23 Polyoxometalate complexes with antitumor activity

Country Status (1)

Country Link
MD (1) MD4014C2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4282C1 (en) * 2012-12-11 2014-11-30 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Use of polyoxometalate complexes with central selenium atoms as compounds possessing antitumor activity
DE102015000812A1 (en) 2015-01-21 2016-07-21 Smart Material Printing B.V. Hydrous cleaning and personal care products with biocidal activity
DE102015000814A1 (en) 2015-01-21 2016-07-21 Smart Material Printing B.V. Biocide equipment of articles with polyoxometalate micro and / or nanoparticles
DE102015000813A1 (en) 2015-01-21 2016-07-21 Smart Material Printing B.V. Method of destroying drugs and toxins and their metabolites using polyoxometalate micro and / or nanoparticles
WO2016116259A1 (en) 2015-01-21 2016-07-28 Smartmaterialprinting B.V. Biocidal treatment of objects and water-containing cleaning and body-care products with polyoxometalate microparticles and/or nanoparticles
WO2019214841A1 (en) 2018-05-07 2019-11-14 Smart Material Printing B.V. Selective use of polyoxometalates against the infestation of eukaryote cultures, virus cultures and microorganism populations with mollicutes and selectively mollicute-inhibiting and -killing polyoxometalate-containing substances and methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0182317A2 (en) * 1984-11-20 1986-05-28 Nippon Kayaku Kabushiki Kaisha Antineoplastic agent
JPS63107959A (en) * 1985-11-15 1988-05-12 Nippon Kayaku Co Ltd Novel selenium compound
JPH01102023A (en) * 1987-10-16 1989-04-19 Nippon Kayaku Co Ltd Antitumor agent
JPH0228190A (en) * 1988-07-15 1990-01-30 Tsumura & Co Novel selenious acid platinum complex and antitumor agent containing the same complex as active ingredient
US6911470B1 (en) * 1988-09-22 2005-06-28 Raymond F. Schinazi Polyoxometalate compounds as antiviral agents
JPH02134362A (en) * 1988-11-16 1990-05-23 Nippon Kayaku Co Ltd Novel selenium compound
US5302248A (en) * 1992-08-28 1994-04-12 The United States Of America As Represented By The Secretary Of Agriculture Delignification of wood pulp by vanadium-substituted polyoxometalates
JPH11140067A (en) * 1997-10-20 1999-05-25 Oxis Isle Of Man Ltd Use of new organic selenium compound as proxidant, and preparation thereof, pharmaceutical composition and its application
DE19751637A1 (en) * 1997-10-30 1999-05-06 Alexander Dr Manhart Antitumor medicament containing interleukin II, N-acetyl-cysteine and selenium has T-lymphocyte cytotoxicity stimulating activity
DE19825746A1 (en) * 1998-06-09 1999-12-16 Biosyn Arzneimittel Gmbh Combination of selenium-containing compounds with cytostatics
CN1166651C (en) * 2001-06-08 2004-09-15 北京大学药学院 Anti-inflammatory and antineoplastic R-bis or glycophenylpropane isoselenazole substituted compound
RU2185819C1 (en) * 2001-10-18 2002-07-27 Дорофеенко Алла Ивановна Agent showing antitumor effect
WO2004014832A2 (en) * 2002-08-02 2004-02-19 Vanetta S.P.A. Redox process particularly for the production of menadione and use of polyoxometalates
US20050197399A1 (en) * 2003-05-13 2005-09-08 Marwan Fakih Method of augmenting the antitumor activity of anticancer agents
CN1787814A (en) * 2003-05-13 2006-06-14 健康研究股份有限公司 Method for augmenting the antitumor activity of anti-cancer agents
US20060258697A1 (en) * 2003-05-13 2006-11-16 Rustum Youcef M Method of augmenting the antitumor activity of anticancer agents
CN101148445A (en) * 2007-01-26 2008-03-26 温州医学院 Method for preparing o-dihydroxyflavone-selenium complexes and medical use

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4282C1 (en) * 2012-12-11 2014-11-30 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Use of polyoxometalate complexes with central selenium atoms as compounds possessing antitumor activity
DE102015000812A1 (en) 2015-01-21 2016-07-21 Smart Material Printing B.V. Hydrous cleaning and personal care products with biocidal activity
DE102015000814A1 (en) 2015-01-21 2016-07-21 Smart Material Printing B.V. Biocide equipment of articles with polyoxometalate micro and / or nanoparticles
DE102015000813A1 (en) 2015-01-21 2016-07-21 Smart Material Printing B.V. Method of destroying drugs and toxins and their metabolites using polyoxometalate micro and / or nanoparticles
WO2016116259A1 (en) 2015-01-21 2016-07-28 Smartmaterialprinting B.V. Biocidal treatment of objects and water-containing cleaning and body-care products with polyoxometalate microparticles and/or nanoparticles
WO2019214841A1 (en) 2018-05-07 2019-11-14 Smart Material Printing B.V. Selective use of polyoxometalates against the infestation of eukaryote cultures, virus cultures and microorganism populations with mollicutes and selectively mollicute-inhibiting and -killing polyoxometalate-containing substances and methods

Also Published As

Publication number Publication date
MD4014C2 (en) 2010-09-30

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees