MD3576795T2 - Medicament peroral pentru tratamentul glandei tiroide - Google Patents
Medicament peroral pentru tratamentul glandei tiroideInfo
- Publication number
- MD3576795T2 MD3576795T2 MDE20191355T MDE20191355T MD3576795T2 MD 3576795 T2 MD3576795 T2 MD 3576795T2 MD E20191355 T MDE20191355 T MD E20191355T MD E20191355 T MDE20191355 T MD E20191355T MD 3576795 T2 MD3576795 T2 MD 3576795T2
- Authority
- MD
- Moldova
- Prior art keywords
- therapeutic agent
- thyroid therapeutic
- oral thyroid
- oral
- active agents
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title abstract 2
- 210000001685 thyroid gland Anatomy 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- 239000003963 antioxidant agent Substances 0.000 abstract 2
- XUIIKFGFIJCVMT-LBPRGKRZSA-N L-thyroxine Chemical compound IC1=CC(C[C@H]([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-LBPRGKRZSA-N 0.000 abstract 1
- 239000002250 absorbent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 229950008325 levothyroxine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Invenţia se referă la un agent terapeutic tiroidian oral, care conţine levotiroxinăsau la sărurile sale farmaceutic compatibile ca agenţi activi, în combinaţie cu cel puţin un antioxidant şi cel puţin un agent de absorbţie, în care procentul de masă de agenţi activi: antioxidanţi: agentul de adsorbţie constituie 1: 1: 5 - 1: 50: 100.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102017102192 | 2017-02-03 | ||
DE102017122807.1A DE102017122807B4 (de) | 2017-09-29 | 2017-09-29 | Orales Schilddrüsentherapeutikum |
PCT/EP2018/052713 WO2018141938A1 (de) | 2017-02-03 | 2018-02-02 | Orales schilddrüsentherapeutikum |
Publications (1)
Publication Number | Publication Date |
---|---|
MD3576795T2 true MD3576795T2 (ro) | 2021-08-31 |
Family
ID=61256901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDE20191355T MD3576795T2 (ro) | 2017-02-03 | 2018-02-02 | Medicament peroral pentru tratamentul glandei tiroide |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP3576795B1 (ro) |
CN (1) | CN110234356A (ro) |
CR (1) | CR20190352A (ro) |
CY (1) | CY1124264T1 (ro) |
DK (1) | DK3576795T3 (ro) |
DO (1) | DOP2019000199A (ro) |
ES (1) | ES2872249T3 (ro) |
GE (1) | GEP20217241B (ro) |
HR (1) | HRP20210799T1 (ro) |
HU (1) | HUE054988T2 (ro) |
LT (1) | LT3576795T (ro) |
MD (1) | MD3576795T2 (ro) |
NI (1) | NI201900083A (ro) |
PL (1) | PL3576795T3 (ro) |
PT (1) | PT3576795T (ro) |
RS (1) | RS61998B1 (ro) |
SG (1) | SG11201906890TA (ro) |
SI (1) | SI3576795T1 (ro) |
TW (1) | TWI753097B (ro) |
UA (1) | UA124642C2 (ro) |
WO (1) | WO2018141938A1 (ro) |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19541128C2 (de) * | 1995-10-27 | 1997-11-27 | Henning Berlin Gmbh & Co | Stabilisierte schilddrüsenhormonhaltige Arzneimittel |
PL191399B1 (pl) | 1996-10-28 | 2006-05-31 | Gen Mills Inc | Sposób kapsułkowania lub osadzania składnika w osnowie w procesie ciągłym, sposób kapsułkowania i/lub osadzania składników w osnowie opartej na węglowodanach, sposób kapsułkowania i/lub osadzania składników w osnowie oraz kapsułka |
DE19830246A1 (de) | 1998-07-07 | 2000-01-13 | Merck Patent Gmbh | Pharmazeutische Zubereitung |
US20030099699A1 (en) | 2001-11-13 | 2003-05-29 | Hanshew Dwight D. | Storage stable thyroxine active drug formulations and methods for their production |
GB0316206D0 (en) * | 2003-07-10 | 2003-08-13 | Glaxo Group Ltd | Pharmaceutical formulation |
US20090297566A1 (en) | 2004-12-27 | 2009-12-03 | Brinkman Kyle R | Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions |
CN101305099A (zh) * | 2005-09-08 | 2008-11-12 | 夏尔有限责任公司 | 具有提高的生物利用度的t3和t4的前药 |
ATE501059T1 (de) | 2005-10-05 | 2011-03-15 | Berlin Chemie Ag | Pharmazeutische schutzverpackung |
GB0920041D0 (en) * | 2009-11-16 | 2009-12-30 | Univ Aston | Tablet |
DK2885005T3 (en) * | 2012-08-20 | 2018-01-02 | Merck Patent Gmbh | FIXED PHARMACEUTICAL PREPARATION CONTAINING LEVOTHYROXIN |
US8779000B1 (en) | 2013-07-20 | 2014-07-15 | Nilesh Parikh | Saccharide free, storage stable thyroid hormone active drug formulations and methods for their production |
-
2018
- 2018-02-02 GE GEAP201815179A patent/GEP20217241B/en unknown
- 2018-02-02 MD MDE20191355T patent/MD3576795T2/ro unknown
- 2018-02-02 ES ES18706422T patent/ES2872249T3/es active Active
- 2018-02-02 CN CN201880009870.1A patent/CN110234356A/zh active Pending
- 2018-02-02 CR CR20190352A patent/CR20190352A/es unknown
- 2018-02-02 EP EP18706422.5A patent/EP3576795B1/de active Active
- 2018-02-02 LT LTEP18706422.5T patent/LT3576795T/lt unknown
- 2018-02-02 SI SI201830290T patent/SI3576795T1/sl unknown
- 2018-02-02 UA UAA201909466A patent/UA124642C2/uk unknown
- 2018-02-02 PL PL18706422T patent/PL3576795T3/pl unknown
- 2018-02-02 PT PT187064225T patent/PT3576795T/pt unknown
- 2018-02-02 SG SG11201906890TA patent/SG11201906890TA/en unknown
- 2018-02-02 DK DK18706422.5T patent/DK3576795T3/da active
- 2018-02-02 RS RS20210713A patent/RS61998B1/sr unknown
- 2018-02-02 WO PCT/EP2018/052713 patent/WO2018141938A1/de unknown
- 2018-02-02 TW TW107103859A patent/TWI753097B/zh active
- 2018-02-02 HU HUE18706422A patent/HUE054988T2/hu unknown
-
2019
- 2019-07-31 NI NI201900083A patent/NI201900083A/es unknown
- 2019-07-31 DO DO2019000199A patent/DOP2019000199A/es unknown
-
2021
- 2021-05-18 HR HRP20210799TT patent/HRP20210799T1/hr unknown
- 2021-06-17 CY CY20211100541T patent/CY1124264T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP3576795A1 (de) | 2019-12-11 |
CR20190352A (es) | 2019-10-25 |
RS61998B1 (sr) | 2021-07-30 |
GEP20217241B (en) | 2021-04-12 |
SG11201906890TA (en) | 2019-08-27 |
NI201900083A (es) | 2019-10-21 |
EP3576795B1 (de) | 2021-04-07 |
SI3576795T1 (sl) | 2021-07-30 |
LT3576795T (lt) | 2021-07-26 |
UA124642C2 (uk) | 2021-10-20 |
HUE054988T2 (hu) | 2021-10-28 |
PT3576795T (pt) | 2021-06-22 |
CN110234356A (zh) | 2019-09-13 |
DOP2019000199A (es) | 2019-10-31 |
HRP20210799T1 (hr) | 2021-06-25 |
ES2872249T3 (es) | 2021-11-02 |
TWI753097B (zh) | 2022-01-21 |
DK3576795T3 (da) | 2021-06-07 |
CY1124264T1 (el) | 2022-07-22 |
TW201836598A (zh) | 2018-10-16 |
WO2018141938A1 (de) | 2018-08-09 |
PL3576795T3 (pl) | 2021-10-25 |
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