MD3347002T2 - Tratamentul bolii Alzheimer într-o populație specifică de pacienți - Google Patents
Tratamentul bolii Alzheimer într-o populație specifică de pacienți Download PDFInfo
- Publication number
- MD3347002T2 MD3347002T2 MDE20180700T MDE20180700T MD3347002T2 MD 3347002 T2 MD3347002 T2 MD 3347002T2 MD E20180700 T MDE20180700 T MD E20180700T MD E20180700 T MDE20180700 T MD E20180700T MD 3347002 T2 MD3347002 T2 MD 3347002T2
- Authority
- MD
- Moldova
- Prior art keywords
- subject
- apoe4
- treatment
- pharmaceutical composition
- score
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562216404P | 2015-09-10 | 2015-09-10 | |
| US201662290287P | 2016-02-02 | 2016-02-02 | |
| US201662302027P | 2016-03-01 | 2016-03-01 | |
| US201662365809P | 2016-07-22 | 2016-07-22 | |
| PCT/US2016/051091 WO2017044840A1 (en) | 2015-09-10 | 2016-09-09 | Methods of treating neurodegenerative disorders in a particular patient population |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MD3347002T2 true MD3347002T2 (ro) | 2023-10-31 |
Family
ID=58240195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDE20180700T MD3347002T2 (ro) | 2015-09-10 | 2016-09-09 | Tratamentul bolii Alzheimer într-o populație specifică de pacienți |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11191742B2 (https=) |
| EP (2) | EP4275750B1 (https=) |
| JP (4) | JP6789579B2 (https=) |
| KR (2) | KR102547164B1 (https=) |
| CN (3) | CN108289870A (https=) |
| AU (1) | AU2016319107B2 (https=) |
| CA (1) | CA2997376C (https=) |
| DK (1) | DK3347002T3 (https=) |
| ES (1) | ES2952727T3 (https=) |
| FI (1) | FI3347002T3 (https=) |
| HR (1) | HRP20230809T1 (https=) |
| HU (1) | HUE062511T2 (https=) |
| LT (1) | LT3347002T (https=) |
| MD (1) | MD3347002T2 (https=) |
| MX (2) | MX392677B (https=) |
| PL (1) | PL3347002T3 (https=) |
| PT (1) | PT3347002T (https=) |
| RS (1) | RS64481B1 (https=) |
| SI (1) | SI3347002T1 (https=) |
| SM (1) | SMT202300250T1 (https=) |
| WO (1) | WO2017044840A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102645633B1 (ko) | 2014-03-21 | 2024-03-11 | 알제온, 인크. | 신경학적 장애를 치료하는 방법 |
| EP4275750B1 (en) * | 2015-09-10 | 2026-05-06 | Alzheon, Inc. | Treatment of alzheimer's disease in a particular patient population |
| CN114805211B (zh) | 2017-03-21 | 2024-08-23 | 润佳（苏州）医药科技有限公司 | 同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途 |
| CN110003058B (zh) | 2018-01-04 | 2022-01-25 | 润佳（苏州）医药科技有限公司 | 3-((l-缬氨酰基)氨基)-3,3-二氘-1-丙磺酸晶型、制备方法及用途 |
| SI3829568T1 (sl) * | 2018-08-01 | 2024-02-29 | Alzheon, Inc. | Derivati sulfopropanojske kisline za zdravljenje nevrodegenerativnih motenj |
| HUE070101T2 (hu) * | 2018-08-01 | 2025-05-28 | Alzheon Inc | 3-Szulfopropánsav neurodegeneratív rendellenességek kezelésére |
| CN111170901A (zh) * | 2018-11-13 | 2020-05-19 | 润佳（苏州）医药科技有限公司 | 3-((l-缬氨酰基)氨基)-1-丙磺酸晶型、制备方法及其用途 |
| UA129160C2 (uk) * | 2019-06-17 | 2025-01-29 | Алзхеон, Інк. | Спосіб лікування хвороби альцгеймера |
| CN116059192B (zh) | 2019-11-13 | 2024-10-29 | 润佳（苏州）医药科技有限公司 | 同位素富集的3-氨基-1-丙磺酸及其衍生物的用途 |
| JP2024542844A (ja) * | 2021-12-09 | 2024-11-15 | アルツェオン・インコーポレーテッド | アルツハイマー病の処置に使用されるａｌｚ－８０１ |
| WO2023150381A1 (en) * | 2022-02-07 | 2023-08-10 | Alzheon, Inc. | Alz-801 for use in treating a covid-19 associated neurological symptom |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| JP3265577B2 (ja) | 1992-10-13 | 2002-03-11 | デューク・ユニバーシティ | アポリポ蛋白ｅの４型イソ型の測定法 |
| US20050031651A1 (en) | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| US20050142191A1 (en) | 2003-06-23 | 2005-06-30 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| US20060079578A1 (en) | 2003-06-23 | 2006-04-13 | Julie Laurin | Pharmaceutical formulations of amyloid inhibiting compounds |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| SG145784A1 (en) | 2003-08-11 | 2008-09-29 | California Inst Of Techn | Microfluidic large scale integration |
| CA2611586A1 (en) | 2005-04-12 | 2007-06-21 | Neurochem (International) Limited | Pharmaceutical formulations of amyloid inhibiting compounds |
| DK2089417T3 (en) * | 2006-10-12 | 2015-03-23 | Bhi Ltd Partnership | Methods, Compounds, Compositions and Vehicles for Delivery of 3-Amion-1-Propanesulfonic Acid |
| KR101450356B1 (ko) | 2006-11-24 | 2014-10-15 | 에이씨 이뮨 에스.에이. | 알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 ｎ-(메틸)-1ｈ-피라졸-3-아민, ｎ-(메틸)-피리딘-2-아민 및 ｎ-(메틸)-티아졸-2-아민 유도체 |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| US20120009125A1 (en) | 2010-07-06 | 2012-01-12 | Lombard Jay L | Apoe4 and apoj biomarker-based prevention and treatment of dementia |
| ES2705027T3 (es) * | 2010-08-19 | 2019-03-21 | Buck Institute For Age Res | Métodos de tratamiento del deterioro cognitivo leve (DCL) y trastornos relacionados |
| EP2847218A4 (en) * | 2012-05-08 | 2015-12-30 | Univ Ramot | APOE4 ANTIBODY FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES |
| HUE044737T2 (hu) * | 2013-05-06 | 2019-11-28 | Baxalta Inc | Alzheimer-kór szubpopulációk kezelése egyesített immunglubulin G-vel |
| CA2938466C (en) * | 2014-02-08 | 2021-11-02 | Genentech, Inc. | Methods of treating alzheimer's disease |
| KR102645633B1 (ko) | 2014-03-21 | 2024-03-11 | 알제온, 인크. | 신경학적 장애를 치료하는 방법 |
| EP4275750B1 (en) * | 2015-09-10 | 2026-05-06 | Alzheon, Inc. | Treatment of alzheimer's disease in a particular patient population |
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2016
- 2016-09-09 EP EP23176559.5A patent/EP4275750B1/en active Active
- 2016-09-09 KR KR1020227009418A patent/KR102547164B1/ko active Active
- 2016-09-09 ES ES16845181T patent/ES2952727T3/es active Active
- 2016-09-09 FI FIEP16845181.3T patent/FI3347002T3/fi active
- 2016-09-09 HU HUE16845181A patent/HUE062511T2/hu unknown
- 2016-09-09 MX MX2018003023A patent/MX392677B/es unknown
- 2016-09-09 CN CN201680052760.4A patent/CN108289870A/zh active Pending
- 2016-09-09 JP JP2018512564A patent/JP6789579B2/ja active Active
- 2016-09-09 WO PCT/US2016/051091 patent/WO2017044840A1/en not_active Ceased
- 2016-09-09 EP EP16845181.3A patent/EP3347002B1/en active Active
- 2016-09-09 DK DK16845181.3T patent/DK3347002T3/da active
- 2016-09-09 SM SM20230250T patent/SMT202300250T1/it unknown
- 2016-09-09 CN CN202310582365.9A patent/CN116712422A/zh active Pending
- 2016-09-09 LT LTEPPCT/US2016/051091T patent/LT3347002T/lt unknown
- 2016-09-09 HR HRP20230809TT patent/HRP20230809T1/hr unknown
- 2016-09-09 CN CN202310582394.5A patent/CN116712423A/zh active Pending
- 2016-09-09 SI SI201631729T patent/SI3347002T1/sl unknown
- 2016-09-09 US US15/758,405 patent/US11191742B2/en active Active
- 2016-09-09 PL PL16845181.3T patent/PL3347002T3/pl unknown
- 2016-09-09 AU AU2016319107A patent/AU2016319107B2/en active Active
- 2016-09-09 KR KR1020187009381A patent/KR102412997B1/ko active Active
- 2016-09-09 CA CA2997376A patent/CA2997376C/en active Active
- 2016-09-09 PT PT168451813T patent/PT3347002T/pt unknown
- 2016-09-09 RS RS20230603A patent/RS64481B1/sr unknown
- 2016-09-09 MD MDE20180700T patent/MD3347002T2/ro unknown
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2018
- 2018-03-09 MX MX2022003128A patent/MX2022003128A/es unknown
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2020
- 2020-09-28 JP JP2020161995A patent/JP7128536B2/ja active Active
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2021
- 2021-09-17 US US17/477,886 patent/US20220096406A1/en not_active Abandoned
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2022
- 2022-08-12 JP JP2022128786A patent/JP2022145949A/ja active Pending
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2023
- 2023-09-06 US US18/462,238 patent/US20230414541A1/en active Pending
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2025
- 2025-02-17 JP JP2025023627A patent/JP2025065545A/ja active Pending
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