MC2397A1 - Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide - Google Patents

Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide

Info

Publication number
MC2397A1
MC2397A1 MC2323A MC2323A MC2397A1 MC 2397 A1 MC2397 A1 MC 2397A1 MC 2323 A MC2323 A MC 2323A MC 2323 A MC2323 A MC 2323A MC 2397 A1 MC2397 A1 MC 2397A1
Authority
MC
Monaco
Prior art keywords
amino acid
peptide
radioactive
acid sequence
affinity
Prior art date
Application number
MC2323A
Other languages
English (en)
Inventor
Ikuya Seki
Yoshitoshi Itaya
Yoshifumi Shirakami
Komei Washino
Original Assignee
Nihon Mediphysics Co Ltd
Antisoma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd, Antisoma Ltd filed Critical Nihon Mediphysics Co Ltd
Publication of MC2397A1 publication Critical patent/MC2397A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1018—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MC2323A 1994-06-07 1995-11-28 Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide MC2397A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14865594 1994-06-07

Publications (1)

Publication Number Publication Date
MC2397A1 true MC2397A1 (fr) 1996-07-26

Family

ID=15457667

Family Applications (1)

Application Number Title Priority Date Filing Date
MC2323A MC2397A1 (fr) 1994-06-07 1995-11-28 Peptide ayant une affinité pour les tumeurs et agent de diagnostic radioactif et agent thérapeutique radioactif contenant ce peptide

Country Status (11)

Country Link
US (1) US5827498A (fr)
EP (1) EP0700930B1 (fr)
KR (1) KR960000250A (fr)
AT (1) ATE175977T1 (fr)
AU (1) AU684348B2 (fr)
CA (1) CA2151099A1 (fr)
DE (1) DE69507408T2 (fr)
DK (1) DK0700930T3 (fr)
ES (1) ES2138111T3 (fr)
MC (1) MC2397A1 (fr)
TW (1) TW394777B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2165228A1 (fr) * 1994-12-27 1996-06-28 Yoshitoshi Itaya Peptides formant des chelates metalliques et leur utilisation
JP6087289B2 (ja) * 2010-12-14 2017-03-01 レセプタ バイオファーマ エス．エー． Ｎａｐｉ２ｂ輸送体に対するヒト化モノクローナル抗体の相補性決定領域に由来する抗腫瘍ペプチド
EP2858660B1 (fr) 2012-06-06 2018-09-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédé et composition pharmaceutique à utiliser dans le traitement du cancer
WO2019040367A1 (fr) * 2017-08-19 2019-02-28 Ohio State Innovation Foundation Nouveaux agents d'imagerie du cancer à base de peptides
CN107550864B (zh) * 2017-08-23 2020-12-18 科笛生物医药(上海)有限公司 Eppt多肽-聚乙二醇-磷脂复合膜材料、其制备方法及主动靶向脂质体递药系统和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5322678A (en) * 1988-02-17 1994-06-21 Neorx Corporation Alteration of pharmacokinetics of proteins by charge modification
WO1990005142A1 (fr) * 1988-11-10 1990-05-17 Imperial Cancer Research Technology Ltd. Polypeptides
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
ATE188387T1 (de) * 1991-02-08 2000-01-15 Diatide Inc Technetium-99m markierte polypeptide zur bildformung
GB9108652D0 (en) * 1991-04-23 1991-06-12 Antisoma Ltd Immunoreactive compounds

Also Published As

Publication number Publication date
DE69507408D1 (de) 1999-03-04
US5827498A (en) 1998-10-27
TW394777B (en) 2000-06-21
KR960000250A (ko) 1996-01-25
EP0700930B1 (fr) 1999-11-03
AU2049995A (en) 1995-12-14
ES2138111T3 (es) 2000-01-01
CA2151099A1 (fr) 1995-12-08
AU684348B2 (en) 1997-12-11
ATE175977T1 (de) 1999-02-15
EP0700930A1 (fr) 1996-03-13
DK0700930T3 (da) 1999-09-13
DE69507408T2 (de) 2000-05-18

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