MA62094B1 - Formulation solide - Google Patents

Formulation solide

Info

Publication number
MA62094B1
MA62094B1 MA62094A MA62094A MA62094B1 MA 62094 B1 MA62094 B1 MA 62094B1 MA 62094 A MA62094 A MA 62094A MA 62094 A MA62094 A MA 62094A MA 62094 B1 MA62094 B1 MA 62094B1
Authority
MA
Morocco
Prior art keywords
solid formulation
pharmaceutical formulations
active pharmaceutical
pharmaceutical ingredient
methods
Prior art date
Application number
MA62094A
Other languages
English (en)
Inventor
Donghua Zhu
Kristof Leonard KIMPE
Sune Klint Andersen
Matthieu Jean M. Ravelingien
Ivan Henri M. Somers
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Publication of MA62094B1 publication Critical patent/MA62094B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention porte sur des formulations pharmaceutiques comprenant un principe pharmaceutique actif; et un élément parmi un copolymère d'acide méthacrylique ou un dérivé de cellulose, ou une association de ceux-ci, le principe pharmaceutique actif étant un inhibiteur de la réplication du virus de la dengue. Des formes posologiques solides comprenant lesdites formulations pharmaceutiques, leurs procédés de préparation et leur utilisation dans des méthodes de prévention et/ou de traitement et/ou d'inhibition de la réplication virale sont également décrits.
MA62094A 2020-11-04 2021-11-03 Formulation solide MA62094B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/CN2020/126596 WO2022094816A1 (fr) 2020-11-04 2020-11-04 Formulation solide
PCT/CN2021/128521 WO2022095913A1 (fr) 2020-11-04 2021-11-03 Formulation solide
EP21809914.1A EP4240331B1 (fr) 2020-11-04 2021-11-03 Formulation solide

Publications (1)

Publication Number Publication Date
MA62094B1 true MA62094B1 (fr) 2026-06-30

Family

ID=78649077

Family Applications (1)

Application Number Title Priority Date Filing Date
MA62094A MA62094B1 (fr) 2020-11-04 2021-11-03 Formulation solide

Country Status (17)

Country Link
US (1) US20240000749A1 (fr)
EP (1) EP4240331B1 (fr)
JP (1) JP2023548348A (fr)
KR (1) KR20230104226A (fr)
CN (1) CN116685317A (fr)
AU (1) AU2021376584A1 (fr)
CA (1) CA3200538A1 (fr)
CO (1) CO2023005726A2 (fr)
CR (1) CR20230192A (fr)
DO (1) DOP2023000084A (fr)
MA (1) MA62094B1 (fr)
MX (1) MX2023005219A (fr)
PE (1) PE20231946A1 (fr)
RS (1) RS68223B1 (fr)
TW (1) TWI923631B (fr)
UY (1) UY39503A (fr)
WO (2) WO2022094816A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202428307A (zh) * 2022-10-12 2024-07-16 日商中外製藥股份有限公司 包含胜肽、界面活性劑及聚合物的組成物
WO2025253267A1 (fr) 2024-06-06 2025-12-11 Janssen Pharmaceuticals, Inc. Combinaison de mosnodenvir et d'analogues proches avec nitd-688 pour une utilisation dans le traitement et la prévention de la dengue
WO2026018176A1 (fr) 2024-07-17 2026-01-22 Janssen Pharmaceuticals, Inc. 2-(4-chloro-2méthoxyphényl)-2-((3-méthoxy-5-(méthylsulfonyl)phényl)amino)-1-(5-(trifluoro méthoxy)-1h-indol-3-yl)éthanone et compositions pharmaceutiques les comprenant

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118587A1 (fr) * 2004-06-02 2005-12-15 Takeda Pharmaceutical Company Limited Dérivé d’indole et usage pour le traitement du cancer
WO2010143207A1 (fr) * 2009-06-11 2010-12-16 Rubicon Research Private Limited Compositions orales à goût masqué d'antiviraux de grippe
WO2011080716A2 (fr) * 2010-01-04 2011-07-07 Wockhardt Limited Composition pharmaceutique pour l'administration modifiée de principes actifs
MX364946B (es) * 2012-04-04 2019-05-15 Vaxform Llc Sistema adyuvante mejorado para la administración de vacunas orales.
CA2893318A1 (fr) * 2012-12-07 2014-06-12 Siga Technologies, Inc. Derives de thienopyridine pour le traitement et la prevention d'infections par le virus de la dengue
CN113209024A (zh) * 2013-12-31 2021-08-06 阿森迪亚制药有限责任公司 疏水性化合物的药物组合物
JP6630887B2 (ja) * 2014-06-13 2020-01-15 国立研究開発法人農業・食品産業技術総合研究機構 ウイルス複製阻害剤
MX2017011469A (es) * 2015-03-10 2018-01-23 Shionogi Inc Dispersiones sólidas.
JOP20160086B1 (ar) * 2015-05-08 2021-08-17 2 Katholieke Univ Leuven Ku Leuven Research And Development مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك
CN105168166A (zh) * 2015-09-08 2015-12-23 深圳信立泰药业股份有限公司 用于治疗心血管疾病固体制剂的包衣技术
EP3305289A1 (fr) * 2016-10-06 2018-04-11 Philipps-Universität Marburg Utilisation de silvestrol, épisilvestrol et silvestrol analoga pour le traitement d'infections virales provoquées par des virus avec traduction dépendante de la coiffe
WO2018213365A1 (fr) * 2017-05-15 2018-11-22 Dana-Farber Cancer Institute, Inc. Composés pour le traitement d'une infection par le virus de la dengue et d'autres infections virales
CA3075729A1 (fr) * 2017-09-14 2019-03-21 Phoenix Biotechnology, Inc. Utilisation d'oleandrine pour traiter une infection virale
IL316312A (en) * 2017-12-07 2024-12-01 Merck Sharp ַ& Dohme Llc Dengue virus vaccine compound formulations
US20190365738A1 (en) * 2018-05-21 2019-12-05 Cadila Healthcare Limited Amorphous solid dispersion of valbenazine tosylate and process for preparation thereof
BR112021004931A2 (pt) * 2018-09-18 2021-06-01 Metacrine, Inc. formas cristalinas de um agonista de receptor farnesoide x
KR102173092B1 (ko) * 2018-11-20 2020-11-02 중앙대학교 산학협력단 루테인 장용성 고체분산체를 유효성분으로 함유하는 위산보호용 조성물 및 이를 포함하는 경구용 제제
CN111407728B (zh) * 2020-04-16 2022-02-22 重庆市畜牧科学院 一种替米考星肠溶性固体分散体及其制备方法和应用

Also Published As

Publication number Publication date
EP4240331A1 (fr) 2023-09-13
RS68223B1 (en) 2026-07-31
CN116685317A (zh) 2023-09-01
WO2022095913A1 (fr) 2022-05-12
DOP2023000084A (es) 2023-11-15
PE20231946A1 (es) 2023-12-05
TWI923631B (zh) 2026-05-01
EP4240331C0 (fr) 2026-04-29
US20240000749A1 (en) 2024-01-04
CO2023005726A2 (es) 2023-05-29
AU2021376584A1 (en) 2023-06-29
EP4240331B1 (fr) 2026-04-29
WO2022094816A1 (fr) 2022-05-12
UY39503A (es) 2022-05-31
KR20230104226A (ko) 2023-07-07
TW202233178A (zh) 2022-09-01
JP2023548348A (ja) 2023-11-16
MX2023005219A (es) 2023-07-25
CA3200538A1 (fr) 2022-05-12
CR20230192A (es) 2023-10-26