MA53448A - Composés agonistes des récepteurs bêta des hormones thyroïdiennes - Google Patents

Composés agonistes des récepteurs bêta des hormones thyroïdiennes

Info

Publication number
MA53448A
MA53448A MA053448A MA53448A MA53448A MA 53448 A MA53448 A MA 53448A MA 053448 A MA053448 A MA 053448A MA 53448 A MA53448 A MA 53448A MA 53448 A MA53448 A MA 53448A
Authority
MA
Morocco
Prior art keywords
receptor agonist
thyroid hormone
beta receptor
agonist compounds
hormone beta
Prior art date
Application number
MA053448A
Other languages
English (en)
French (fr)
Inventor
Randall Halcomb
Thorsten A Kirschberg
F Anthony Romero
Yingzi Xu
Original Assignee
Terns Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terns Inc filed Critical Terns Inc
Publication of MA53448A publication Critical patent/MA53448A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
MA053448A 2018-08-24 2019-08-23 Composés agonistes des récepteurs bêta des hormones thyroïdiennes MA53448A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862722312P 2018-08-24 2018-08-24
US201962867117P 2019-06-26 2019-06-26

Publications (1)

Publication Number Publication Date
MA53448A true MA53448A (fr) 2022-04-20

Family

ID=69584321

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053448A MA53448A (fr) 2018-08-24 2019-08-23 Composés agonistes des récepteurs bêta des hormones thyroïdiennes

Country Status (9)

Country Link
US (2) US10800767B2 (https=)
EP (1) EP3840755B1 (https=)
JP (2) JP7579253B2 (https=)
CN (1) CN112805005A (https=)
AU (2) AU2019325656B2 (https=)
CA (1) CA3110520A1 (https=)
MA (1) MA53448A (https=)
TW (1) TWI837169B (https=)
WO (1) WO2020041741A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI840423B (zh) 2018-10-12 2024-05-01 美商拓臻股份有限公司 甲狀腺素受體β促效劑化合物
CN111320609A (zh) 2018-12-13 2020-06-23 拓臻股份有限公司 一种THRβ受体激动剂化合物及其制备方法和用途
GEP20247637B (en) 2019-05-08 2024-06-25 Aligos Therapeutics Inc Modulators of thr-b and methods of use thereof
WO2020228577A1 (zh) * 2019-05-10 2020-11-19 深圳微芯生物科技股份有限公司 一种哒嗪酮衍生物及其应用
AU2020336272A1 (en) 2019-08-23 2022-04-14 Terns Pharmaceuticals, Inc. Thyroid hormone receptor beta agonist compounds
CN114375193B (zh) 2019-09-12 2024-05-14 拓臻制药公司 甲状腺激素受体β激动剂化合物
CN114437034A (zh) * 2020-11-06 2022-05-06 深圳微芯生物科技股份有限公司 一种酞嗪类化合物的可药用盐、晶型及其制备方法
CN116670118B (zh) 2020-11-13 2026-02-06 伊尼制药公司 二氯苯酚hsd17b13抑制剂及其用途
CN114621207B (zh) * 2020-12-11 2025-02-11 广东东阳光药业股份有限公司 一种作为甲状腺激素β受体激动剂的化合物及其用途
CA3212130A1 (en) * 2021-03-03 2022-09-09 Terns Pharmaceuticals, Inc. Thyroid hormone receptor beta agonist compounds
WO2022194278A1 (zh) * 2021-03-19 2022-09-22 南京明德新药研发有限公司 双环苯酚类化合物及其应用
CN117624154A (zh) * 2021-03-19 2024-03-01 南京明德新药研发有限公司 双环吡啶酮类化合物及其应用
US20240398794A1 (en) 2023-04-07 2024-12-05 Terns Pharmaceuticals, Inc. COMBINATIONS OF GLP-1R AND THRß AGONISTS AND METHODS OF USE THEREOF
CN116554063B (zh) * 2023-05-23 2025-03-07 江苏省农用激素工程技术研究中心有限公司 氟胺磺隆中间体的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7230031B2 (en) 2002-01-30 2007-06-12 Kissei Pharmaceutical Co., Ltd. Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof
GB0327319D0 (en) * 2003-11-24 2003-12-24 Pfizer Ltd Novel pharmaceuticals
US7572799B2 (en) * 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
PL1919878T3 (pl) * 2005-07-21 2011-03-31 Hoffmann La Roche Pochodne pirydazynonu jako agoniści receptora hormonu tarczycy
WO2007132475A1 (en) 2006-05-15 2007-11-22 Cadila Healthcare Limited Selective tr-beta 1 agonist
US8394811B2 (en) * 2007-04-18 2013-03-12 Molsoft Llc Hydrazide compounds as thyroid hormone receptor modulators and uses thereof
TWI698430B (zh) * 2015-02-13 2020-07-11 南北兄弟藥業投資有限公司 三環化合物及其在藥物中的應用
CN109574995B (zh) 2018-01-23 2020-07-24 深圳市塔吉瑞生物医药有限公司 取代的哒嗪酮化合物
CN111801324B (zh) 2018-06-12 2021-10-22 四川海思科制药有限公司 甲状腺激素受体激动剂及其用途
US12391677B2 (en) 2018-10-12 2025-08-19 InventisBio Co., Ltd. Thyroid hormone receptor agonists

Also Published As

Publication number Publication date
AU2019325656B2 (en) 2025-04-24
CA3110520A1 (en) 2020-02-27
TWI837169B (zh) 2024-04-01
EP3840755A4 (en) 2022-04-20
JP2025020206A (ja) 2025-02-12
CN112805005A (zh) 2021-05-14
JP7846735B2 (ja) 2026-04-15
EP3840755B1 (en) 2026-02-18
EP3840755A1 (en) 2021-06-30
JP2021535207A (ja) 2021-12-16
AU2025206402A1 (en) 2025-08-07
US10800767B2 (en) 2020-10-13
AU2019325656A1 (en) 2021-03-11
US20200062742A1 (en) 2020-02-27
TW202023560A (zh) 2020-07-01
JP7579253B2 (ja) 2024-11-07
WO2020041741A1 (en) 2020-02-27
US20250236615A1 (en) 2025-07-24

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