MA53868A - Composés agonistes du récepteur bêta des hormones thyroïdiennes - Google Patents
Composés agonistes du récepteur bêta des hormones thyroïdiennesInfo
- Publication number
- MA53868A MA53868A MA053868A MA53868A MA53868A MA 53868 A MA53868 A MA 53868A MA 053868 A MA053868 A MA 053868A MA 53868 A MA53868 A MA 53868A MA 53868 A MA53868 A MA 53868A
- Authority
- MA
- Morocco
- Prior art keywords
- receptor agonist
- thyroid hormone
- beta receptor
- agonist compounds
- hormone beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862745195P | 2018-10-12 | 2018-10-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA53868A true MA53868A (fr) | 2021-08-18 |
Family
ID=70161488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA053868A MA53868A (fr) | 2018-10-12 | 2019-10-10 | Composés agonistes du récepteur bêta des hormones thyroïdiennes |
Country Status (10)
Country | Link |
---|---|
US (2) | US11203587B2 (fr) |
EP (1) | EP3863635A4 (fr) |
JP (1) | JP2022504620A (fr) |
CN (1) | CN112839655A (fr) |
AR (1) | AR116694A1 (fr) |
AU (1) | AU2019357618A1 (fr) |
CA (1) | CA3114015A1 (fr) |
MA (1) | MA53868A (fr) |
TW (1) | TWI840423B (fr) |
WO (1) | WO2020077123A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111320609A (zh) | 2018-12-13 | 2020-06-23 | 拓臻股份有限公司 | 一种THRβ受体激动剂化合物及其制备方法和用途 |
EP3965884A1 (fr) | 2019-05-08 | 2022-03-16 | Aligos Therapeutics, Inc. | Modulateurs de thr-beta et leurs procédés d'utilisation |
CN113278013B (zh) * | 2020-02-20 | 2022-09-23 | 昆药集团股份有限公司 | 2,6-二取代的1,2,4-三嗪-3,5-二酮化合物及其制备方法和应用 |
AU2021283577A1 (en) * | 2020-06-02 | 2023-01-19 | Chengdu Kanghong Pharmaceutical Co., Ltd. | Novel thyroid hormone β receptor agonist |
WO2022053028A1 (fr) * | 2020-09-10 | 2022-03-17 | 南京明德新药研发有限公司 | Composé de 1,2,4-triazine-3,5-(2h,4h)-dicétone et son utilisation |
CN112645936B (zh) * | 2020-12-17 | 2022-03-01 | 山东第一医科大学(山东省医学科学院) | 取代的哒嗪酮类化合物及其用途 |
PE20240097A1 (es) * | 2021-03-03 | 2024-01-18 | Terns Pharmaceuticals Inc | Compuestos agonistas beta del receptor de la hormona tiroidea |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6787652B1 (en) | 1999-09-30 | 2004-09-07 | Pfizer, Inc. | 6-Azauracil derivatives as thyroid receptor ligands |
ATE297905T1 (de) * | 1999-09-30 | 2005-07-15 | Pfizer Prod Inc | 6-azauracilderivate als liganden der thyroidrezeptoren |
EP1471049A4 (fr) | 2002-01-30 | 2006-08-16 | Kissei Pharmaceutical | Nouveau ligand de recepteur de l'hormone thyroidienne, preparations medicinales le contenant et leur utilisation |
AU2003225305A1 (en) | 2002-05-08 | 2003-11-11 | Bristol-Myers Squibb Company | Pyridine-based thyroid receptor ligands |
US7572799B2 (en) | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
FR2882750B1 (fr) | 2005-03-03 | 2007-05-11 | Pierre Fabre Medicament Sa | Derives de 1,2,4-triazines, leur preparation et leur application en therapeutique humaine |
GB0513692D0 (en) | 2005-07-04 | 2005-08-10 | Karobio Ab | Novel pharmaceutical compositions |
AU2006271721C1 (en) * | 2005-07-21 | 2013-09-19 | F. Hoffmann-La Roche Ag | Pyridazinone derivatives as thyroid hormone receptor agonists |
FR2933979B1 (fr) * | 2008-07-15 | 2012-08-24 | Pf Medicament | Derives de triazines et uraciles, leur preparation et leur application en therapeutique humaine |
CN102459185B (zh) | 2009-04-20 | 2015-06-03 | 田边三菱制药株式会社 | 新型甲状腺激素β受体激动剂 |
WO2011038207A1 (fr) | 2009-09-25 | 2011-03-31 | Metabasis Therapeutics, Inc. | Agonistes des récepteurs des hormones thyroïdiennes contenant du phosphore et méthodes d'utilisation |
KR20140090678A (ko) * | 2011-11-14 | 2014-07-17 | 세파론, 인코포레이티드 | AXL 및 c-MET 키나제 억제제로서의 우라실 유도체 |
CN103130723B (zh) | 2011-11-30 | 2015-01-14 | 成都地奥制药集团有限公司 | 一种多聚(adp-核糖)聚合酶抑制剂 |
EP3189046B1 (fr) * | 2014-09-05 | 2020-08-26 | Genentech, Inc. | Composés thérapeutiques et leurs utilisations |
MX2019004492A (es) | 2016-10-18 | 2019-11-18 | Madrigal Pharmaceuticals Inc | Metodos para tratar trastornos del higado o trastornos lipidicos con un agonista de thr-beta. |
WO2019144835A1 (fr) | 2018-01-23 | 2019-08-01 | 深圳市塔吉瑞生物医药有限公司 | Composé de pyridazinone substitué |
CN113683597A (zh) | 2018-06-12 | 2021-11-23 | 四川海思科制药有限公司 | 甲状腺激素受体激动剂及其用途 |
JP2021535207A (ja) | 2018-08-24 | 2021-12-16 | ターンズ・インコーポレイテッドTerns, Inc. | 甲状腺ホルモン受容体ベータアゴニスト化合物 |
US20210355110A1 (en) | 2018-10-12 | 2021-11-18 | InventisBio Co., Ltd. | Thyroid hormone receptor agonists |
CN111320609A (zh) | 2018-12-13 | 2020-06-23 | 拓臻股份有限公司 | 一种THRβ受体激动剂化合物及其制备方法和用途 |
CN111484481A (zh) | 2019-01-26 | 2020-08-04 | 察略盛医药科技(上海)有限公司 | 哒嗪酮类衍生物、其制备方法及其在医药上的用途 |
CN113474335A (zh) | 2019-02-21 | 2021-10-01 | 南京瑞捷医药科技有限公司 | 新型化合物及其作为甲状腺激素受体激动剂的用途 |
CN114174282A (zh) | 2019-05-29 | 2022-03-11 | 南京明德新药研发有限公司 | 作为甲状腺素受体-β激动剂的哒嗪酮类衍生物及其应用 |
-
2019
- 2019-10-09 TW TW108136747A patent/TWI840423B/zh active
- 2019-10-10 WO PCT/US2019/055689 patent/WO2020077123A1/fr unknown
- 2019-10-10 CA CA3114015A patent/CA3114015A1/fr active Pending
- 2019-10-10 US US16/598,978 patent/US11203587B2/en active Active
- 2019-10-10 AU AU2019357618A patent/AU2019357618A1/en active Pending
- 2019-10-10 CN CN201980067301.7A patent/CN112839655A/zh active Pending
- 2019-10-10 JP JP2021519726A patent/JP2022504620A/ja active Pending
- 2019-10-10 EP EP19870196.3A patent/EP3863635A4/fr active Pending
- 2019-10-10 MA MA053868A patent/MA53868A/fr unknown
- 2019-10-11 AR ARP190102912A patent/AR116694A1/es unknown
-
2022
- 2022-06-30 US US17/855,672 patent/US20220348561A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
TW202027748A (zh) | 2020-08-01 |
AU2019357618A1 (en) | 2021-04-29 |
CA3114015A1 (fr) | 2020-04-16 |
JP2022504620A (ja) | 2022-01-13 |
US20220348561A1 (en) | 2022-11-03 |
US11203587B2 (en) | 2021-12-21 |
WO2020077123A1 (fr) | 2020-04-16 |
EP3863635A1 (fr) | 2021-08-18 |
TWI840423B (zh) | 2024-05-01 |
CN112839655A (zh) | 2021-05-25 |
US20200115362A1 (en) | 2020-04-16 |
EP3863635A4 (fr) | 2022-06-15 |
AR116694A1 (es) | 2021-06-02 |
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