MA53130A - Procédés d'atténuation d'interférence de cible médicamenteuse dans un dosage immunologique d'anticorps anti-médicament (ada) - Google Patents

Procédés d'atténuation d'interférence de cible médicamenteuse dans un dosage immunologique d'anticorps anti-médicament (ada)

Info

Publication number
MA53130A
MA53130A MA053130A MA53130A MA53130A MA 53130 A MA53130 A MA 53130A MA 053130 A MA053130 A MA 053130A MA 53130 A MA53130 A MA 53130A MA 53130 A MA53130 A MA 53130A
Authority
MA
Morocco
Prior art keywords
drug
ada
interference mitigation
immunological assay
mitigation methods
Prior art date
Application number
MA053130A
Other languages
English (en)
Inventor
Jihua Chen
Sumner Giane Oliveira
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MA53130A publication Critical patent/MA53130A/fr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MA053130A 2018-07-10 2019-07-09 Procédés d'atténuation d'interférence de cible médicamenteuse dans un dosage immunologique d'anticorps anti-médicament (ada) MA53130A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862696016P 2018-07-10 2018-07-10

Publications (1)

Publication Number Publication Date
MA53130A true MA53130A (fr) 2021-05-19

Family

ID=67544324

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053130A MA53130A (fr) 2018-07-10 2019-07-09 Procédés d'atténuation d'interférence de cible médicamenteuse dans un dosage immunologique d'anticorps anti-médicament (ada)

Country Status (14)

Country Link
US (1) US20200018770A1 (fr)
EP (1) EP3821255A1 (fr)
JP (1) JP2024045646A (fr)
KR (1) KR20210031854A (fr)
CN (1) CN112384808A (fr)
AU (1) AU2019301614A1 (fr)
BR (1) BR112020022912A2 (fr)
CA (1) CA3098206A1 (fr)
EA (1) EA202190237A1 (fr)
IL (1) IL277888A (fr)
MA (1) MA53130A (fr)
MX (1) MX2021000331A (fr)
SG (1) SG11202011283TA (fr)
WO (1) WO2020014194A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220156023A (ko) * 2020-03-17 2022-11-24 리제너론 파아마슈티컬스, 인크. 항-약물 항체 검정에서의 표적 간섭 완화
CN114047343B (zh) * 2022-01-13 2022-05-31 美迪西普亚医药科技(上海)有限公司 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用
WO2024044622A1 (fr) * 2022-08-24 2024-02-29 Amgen Inc. Dosages d'anticorps anti-médicament
CN115586337A (zh) * 2022-09-14 2023-01-10 杭州赛基生物科技有限公司 检测肿瘤伴随诊断相关因子的试剂盒及其制备方法
WO2024064044A1 (fr) * 2022-09-23 2024-03-28 Merck Sharp & Dohme Llc Procédé de dosage d'anticorps de neutralisation
CN117805382B (zh) * 2024-02-28 2024-05-03 军科正源(北京)药物研究有限责任公司 检测抗利妥昔单抗中和抗体的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6454356A (en) * 1987-08-26 1989-03-01 Meidensha Electric Mfg Co Ltd Method for suppressing non-specific adsorption of antibody to solid phase antigen
WO2009022001A1 (fr) * 2007-08-16 2009-02-19 Novartis Ag Amélioration de la tolérance à un médicament dans un test d'immunogénicité
WO2012175741A2 (fr) * 2011-06-23 2012-12-27 Ablynx Nv Techniques permettant de prédire, détecter et réduire une interférence protéinique spécifique dans des dosages impliquant des domaines variables uniques d'immunoglobuline
RU2674996C2 (ru) * 2013-07-04 2018-12-14 Ф. Хоффманн-Ля Рош Аг Иммуноферментный анализ с подавлением интерференции для определения антител к лекарствам в образцах сыворотки
MX2016010413A (es) * 2014-02-11 2016-11-30 Genzyme Corp Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco.
WO2017096262A1 (fr) * 2015-12-04 2017-06-08 Jomoco, Corp. Compositions et procédés pour atténuer ou prévenir une réponse immunitaire à une molécule thérapeutique immunogène chez des primates non humains
US20190145985A1 (en) * 2017-11-10 2019-05-16 BioAgilytix Labs, LLC Method for eliminating target interference
JP7161534B2 (ja) * 2017-11-29 2022-10-26 エフ.ホフマン-ラ ロシュ アーゲー 標的による干渉が抑制された抗薬物抗体アッセイ

Also Published As

Publication number Publication date
WO2020014194A1 (fr) 2020-01-16
BR112020022912A2 (pt) 2021-02-23
MX2021000331A (es) 2021-03-25
CA3098206A1 (fr) 2020-01-16
CN112384808A (zh) 2021-02-19
AU2019301614A1 (en) 2020-10-22
US20200018770A1 (en) 2020-01-16
JP2021531448A (ja) 2021-11-18
KR20210031854A (ko) 2021-03-23
IL277888A (en) 2020-11-30
SG11202011283TA (en) 2020-12-30
EP3821255A1 (fr) 2021-05-19
EA202190237A1 (ru) 2021-04-15
JP2024045646A (ja) 2024-04-02

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