MA52618A - Benzamides substitués par 1,3-thiazol-2-yle pour le traitement de maladies associées à la sensibilisation des fibres nerveuses - Google Patents

Benzamides substitués par 1,3-thiazol-2-yle pour le traitement de maladies associées à la sensibilisation des fibres nerveuses

Info

Publication number
MA52618A
MA52618A MA052618A MA52618A MA52618A MA 52618 A MA52618 A MA 52618A MA 052618 A MA052618 A MA 052618A MA 52618 A MA52618 A MA 52618A MA 52618 A MA52618 A MA 52618A
Authority
MA
Morocco
Prior art keywords
yle
thiazol
treatment
diseases associated
fiber sensitization
Prior art date
Application number
MA052618A
Other languages
English (en)
Inventor
Damian Brockschnieder
Oliver Martin Fischer
Christian Friedrich
Isabella Gashaw
Original Assignee
Bayer Ag
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag
Publication of MA52618A publication Critical patent/MA52618A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
MA052618A 2018-05-15 2019-05-14 Benzamides substitués par 1,3-thiazol-2-yle pour le traitement de maladies associées à la sensibilisation des fibres nerveuses MA52618A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18172409 2018-05-15

Publications (1)

Publication Number Publication Date
MA52618A true MA52618A (fr) 2021-04-21

Family

ID=62186254

Family Applications (1)

Application Number Title Priority Date Filing Date
MA052618A MA52618A (fr) 2018-05-15 2019-05-14 Benzamides substitués par 1,3-thiazol-2-yle pour le traitement de maladies associées à la sensibilisation des fibres nerveuses

Country Status (16)

Country Link
US (1) US20210220358A1 (fr)
EP (1) EP3793554A1 (fr)
JP (1) JP2021523919A (fr)
KR (1) KR20210009341A (fr)
CN (1) CN112334132A (fr)
AU (1) AU2019269049A1 (fr)
BR (1) BR112020022553A2 (fr)
CA (1) CA3100099A1 (fr)
CL (1) CL2020002939A1 (fr)
EA (1) EA202092678A1 (fr)
JO (1) JOP20200286A1 (fr)
MA (1) MA52618A (fr)
MX (1) MX2020012202A (fr)
SG (1) SG11202011010YA (fr)
TW (1) TWI780329B (fr)
WO (1) WO2019219674A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10174016B2 (en) 2014-12-09 2019-01-08 Beyer Aktiengesellschaft 1,3-thiazol-2-yl substituted benzamides
AU2019353424B2 (en) 2018-10-05 2022-12-08 Shionogi & Co., Ltd. Medicine for treating chronic cough
EP3757103A1 (fr) * 2019-06-27 2020-12-30 Bayer AG Analogues de 3-(5-méthyl-1,3-thiazol-2-yl)-n-{(1r)-1-[2-(trifluoro-méthyl)pyrimidin-5-yl]éthyl}benzamide pour le traitement des maladies neurogeniques
CN113082023B (zh) * 2019-12-23 2024-03-01 武汉朗来科技发展有限公司 P2x3抑制剂和p2x4抑制剂的药物组合及其应用
WO2021238834A1 (fr) * 2020-05-25 2021-12-02 中国医药研究开发中心有限公司 Composé arylformamide et son procédé de préparation et son utilisation médicale
JP2023543066A (ja) * 2020-09-30 2023-10-12 ヒューマンウェル ヘルスケア （グループ） カンパニー リミテッド ベンザミド類化合物及びその使用
WO2022253943A1 (fr) 2021-06-04 2022-12-08 Bayer Aktiengesellschaft Formes cristallines de 3-(5-méthyl-1,3-thiazol-2-yl)-5-[(3r)-tétrahydrofuran-3-yloxy]-n-{(1r)-1-[2-(trifluoro-méthyl)pyrimidin-5-yl]éthyl}-benzamide
WO2022253945A1 (fr) 2021-06-04 2022-12-08 Bayer Aktiengesellschaft Formes posologiques pharmaceutiques comprenant du 3-(5-méthyl-1,3-thiazol-2-yl)-5-[(3r)-tétrahydrofuran-3-yloxy]-n-{(1r)-1-[2-(trifluorométhyl)pyrimidin-5-yl]éthyl}-benzamide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5011472A (en) 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
EP2262766B1 (fr) * 2008-02-29 2015-11-11 Evotec AG Composés amides, compositions à base de ces composés et leurs utilisations
MX367657B (es) 2013-08-23 2019-08-30 Afferent Pharmaceuticals Inc Moduladores del receptor p2x3 y p2x2/3 de diaminopiridina para el tratamiento de la tos aguda, sub-aguda o crónica.
US10174016B2 (en) * 2014-12-09 2019-01-08 Beyer Aktiengesellschaft 1,3-thiazol-2-yl substituted benzamides
US10183937B2 (en) * 2014-12-09 2019-01-22 Bayer Aktiengesellschaft 1,3-thiazol-2-yl substituted benzamides
RS64155B1 (sr) * 2015-09-29 2023-05-31 Afferent Pharmaceuticals Inc Diaminopirimidinski modulatori p2x3 i p2x2/3 receptora, za upotrebu u lečenju kašlja
EA202092680A1 (ru) * 2018-05-15 2021-04-13 Байер Акциенгезельшафт 1,3-тиазол-2-ил-замещенные бензамиды для лечения заболеваний, ассоциированных с сенситизацией нервных волокон

Also Published As

Publication number Publication date
SG11202011010YA (en) 2020-12-30
EP3793554A1 (fr) 2021-03-24
CL2020002939A1 (es) 2021-03-05
CA3100099A1 (fr) 2019-11-21
KR20210009341A (ko) 2021-01-26
MX2020012202A (es) 2021-01-29
CN112334132A (zh) 2021-02-05
TW201946924A (zh) 2019-12-16
AU2019269049A1 (en) 2020-11-26
TWI780329B (zh) 2022-10-11
JOP20200286A1 (ar) 2020-11-09
US20210220358A1 (en) 2021-07-22
BR112020022553A2 (pt) 2021-02-02
EA202092678A1 (ru) 2021-04-12
JP2021523919A (ja) 2021-09-09
WO2019219674A1 (fr) 2019-11-21

Similar Documents

Publication Publication Date Title
MA52618A (fr) Benzamides substitués par 1,3-thiazol-2-yle pour le traitement de maladies associées à la sensibilisation des fibres nerveuses
MA52616A (fr) Benzamides à substitution 1,3-thiazol-2-yl pour le traitement de maladies associées à la sensibilisation de fibres nerveuses
MA51673A (fr) Composés destinés au traitement de troubles dépendant de la kinase
MA49402A (fr) Polynucléotides aadc pour le traitement de la maladie de parkinson
PH12018500087A1 (en) 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as magl inhibitors
DOP2019000241A (es) ANTICUERPOS ANTI-PÉPTIDO BETA AMILOIDE N3pGlu Y SUS USOS
BR112021016620A2 (pt) Azepino-indóis e outros heterociclos para o tratamento de distúrbios cerebrais
MA52778A (fr) Méthodes de traitement de troubles associés au récepteur s1p1
MA46018A (fr) Activateurs d'édition du génome
MA55974A (fr) Composés triaryles pour le traitement de maladies pd-l1
MA51524A (fr) Composés, compositions et méthodes pour le traitement de maladies impliquant des tissus malades acides ou hypoxiques
EA202090510A1 (ru) Способ лечения бокового амиотрофического склероза придопидином
MA49664A (fr) Combinaisons d'un dérivé de 4-pyrimidinesulfamide avec des principes actifs pour le traitement de maladies liées à l'endothéline
MA56387A (fr) Dérivés de quinazoline-4-one utiles pour le traitement de maladies et de troubles associés à braf
BR112018011308A2 (pt) anticorpos de peptídeo de beta amiloide anti-n3pglu e usos dos mesmos
BR112022016382A2 (pt) Triptaminas específicas para o uso no tratamento de doenças do humor
MA51672A (fr) Composés destinés au traitement des troubles kinases-dépendants
MA52415A (fr) Dérivés de triazine pour le traitement de maladies associées à des neurotrophines
MA51738A (fr) Composés pour le traitement de la douleur
MA42953A (fr) Composés et compositions pour le traitement de troubles oculaires
MA54077A (fr) Polythérapie pour le traitement de maladies hématologiques
MA51628A (fr) Méthode de traitement de troubles de l'équilibre acido-basique
EA201990450A1 (ru) Ингибиторы киназы, содержащей домен с двумя лейциновыми "застежками-молниями" (dlk), для лечения заболевания
EP4285993A3 (fr) Facteur de différentiation de croissance 15 en tant que biomarqueur de metformine
MA51136A (fr) Traitement des maladies monogéniques à l'aide d'un anticorps anti-cd45rc