MA50533A - Imipridones pour gliomes - Google Patents

Imipridones pour gliomes

Info

Publication number
MA50533A
MA50533A MA050533A MA50533A MA50533A MA 50533 A MA50533 A MA 50533A MA 050533 A MA050533 A MA 050533A MA 50533 A MA50533 A MA 50533A MA 50533 A MA50533 A MA 50533A
Authority
MA
Morocco
Prior art keywords
imipridones
gliomas
Prior art date
Application number
MA050533A
Other languages
English (en)
Inventor
Joshua E Allen
Varun Vijay Prabhu
Martin Stogniew
Original Assignee
Oncoceutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncoceutics Inc filed Critical Oncoceutics Inc
Publication of MA50533A publication Critical patent/MA50533A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA050533A 2017-11-03 2018-11-05 Imipridones pour gliomes MA50533A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762581478P 2017-11-03 2017-11-03
US15/947,840 US10172862B2 (en) 2017-01-30 2018-04-08 Imipridones for gliomas

Publications (1)

Publication Number Publication Date
MA50533A true MA50533A (fr) 2020-09-09

Family

ID=63038820

Family Applications (1)

Application Number Title Priority Date Filing Date
MA050533A MA50533A (fr) 2017-11-03 2018-11-05 Imipridones pour gliomes

Country Status (14)

Country Link
US (4) US10172862B2 (fr)
EP (1) EP3703681A4 (fr)
JP (2) JP7319989B2 (fr)
KR (1) KR20200117979A (fr)
CN (2) CN111818919A (fr)
AU (1) AU2018360752A1 (fr)
BR (1) BR112020008791A2 (fr)
CA (1) CA3080815A1 (fr)
EA (1) EA202090928A1 (fr)
IL (1) IL274194A (fr)
MA (1) MA50533A (fr)
MX (1) MX2020004375A (fr)
SG (1) SG11202003952YA (fr)
WO (1) WO2019090222A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018009227A (es) 2016-01-29 2018-11-09 Oncoceutics Inc Modulacion del receptor acoplado a proteina g (gpcr) por imipridones.
US10172862B2 (en) 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas
WO2020172485A1 (fr) * 2019-02-22 2020-08-27 Board Of Regents, The University Of Texas System Procédés d'utilisation d'imipridones
JP2023536524A (ja) 2020-08-06 2023-08-25 エトヴェシュ ロラーンド トゥドマニュジェテム 新規イミプリドン誘導体の合成とその抗癌活性の評価
CN113248465B (zh) * 2021-06-16 2021-10-29 中国农业科学院北京畜牧兽医研究所 一种鹰嘴豆芽素a的合成方法
CN114632088B (zh) * 2022-05-16 2022-08-16 北京市神经外科研究所 阿糖胞苷化合物在制备治疗脊髓胶质瘤的药物中的用途
WO2024030645A1 (fr) * 2022-08-05 2024-02-08 Chimerix, Inc. Compositions pharmaceutiques et leurs utilisations pour le traitement du gliome
CN117731654B (zh) * 2024-02-18 2024-05-07 首都医科大学附属北京天坛医院 Jjh201601在初发性脑胶质瘤和复发性脑胶质瘤治疗中的新用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1638178A (en) * 1924-11-04 1927-08-09 Union Switch & Signal Co Railway-traffic-controlling apparatus
US4867973A (en) 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
WO2004082570A2 (fr) 2003-03-17 2004-09-30 Bayer Healthcare Ag Diagnostics et traitements contre des maladies associees au recepteur d2 de la dopamine (drd2)
EP1644536A4 (fr) 2003-07-08 2008-07-23 Univ California Marqueur genetique de reponse a des antipsychotiques atypiques et a des antidepresseurs et leurs methodes d'utilisation
US8088895B2 (en) 2006-10-18 2012-01-03 Chemocentryx, Inc. Antibodies that bind CXCR7 epitopes
CA2699912A1 (fr) * 2007-09-19 2009-03-26 Oncofluor, Inc. Procede d'imagerie et de traitement d'organes et de tissus
US20130102477A1 (en) * 2010-06-23 2013-04-25 Ryan D. Morin Biomarkers for non-hodgkin lymphomas and uses thereof
AU2012222812A1 (en) 2011-02-28 2013-05-02 Mcmaster University Treatment of cancer with dopamine receptor antagonists
SI2701708T1 (sl) 2011-04-29 2020-07-31 The Penn State Research Foundation Induciranje malomolekulskega gena TRAIL z normalnimi in tumorskimi celicami kot terapija proti raku
EP3572083A1 (fr) * 2013-03-13 2019-11-27 Oncoceutics, Inc. 7-benzyl-10-(2-méthylbenzyle)-2,6,7,8,9,10-hexahydroimidazo[1,2-a]pyrido[4,3-d]pyrimidine-5(3h)-on à utiliser dans le traitement du cancer
US9688679B2 (en) * 2013-03-13 2017-06-27 Oncoceutics, Inc. 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-A]pyrido[3,4-E]pyrimidin-5 (1H)-one, salts thereof and methods of using the same in combination therapy
WO2015073072A1 (fr) 2013-11-15 2015-05-21 Oncoceutics, Inc. 7-benzyl-4-(2-méthylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1h)-one
US9376437B2 (en) * 2013-03-13 2016-06-28 Oncoceutics, Inc 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, salts thereof and methods of using the same in combination therapy
CN110669047A (zh) * 2013-11-15 2020-01-10 昂克希尔迪克斯有限公司 用于治疗癌症的化合物、其组合物及应用方法
HUE049013T2 (hu) 2014-03-31 2020-08-28 Scripps Research Inst Farmakofór trail indukcióra
CN104860948B (zh) 2015-05-15 2017-09-26 南京盖特医药技术有限公司 咪唑并嘧啶酮类化合物及其制备方法和应用
MX2018009227A (es) * 2016-01-29 2018-11-09 Oncoceutics Inc Modulacion del receptor acoplado a proteina g (gpcr) por imipridones.
US10172862B2 (en) 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas

Also Published As

Publication number Publication date
MX2020004375A (es) 2020-11-11
CN111818919A (zh) 2020-10-23
CA3080815A1 (fr) 2019-05-09
CN116173036A (zh) 2023-05-30
US20210236499A1 (en) 2021-08-05
JP2021502417A (ja) 2021-01-28
US20180221375A1 (en) 2018-08-09
BR112020008791A2 (pt) 2020-10-20
EA202090928A1 (ru) 2020-08-14
AU2018360752A1 (en) 2020-05-21
US20190183895A1 (en) 2019-06-20
EP3703681A4 (fr) 2021-08-11
US10369154B2 (en) 2019-08-06
KR20200117979A (ko) 2020-10-14
EP3703681A1 (fr) 2020-09-09
US10172862B2 (en) 2019-01-08
JP2023139152A (ja) 2023-10-03
SG11202003952YA (en) 2020-05-28
IL274194A (en) 2020-06-30
JP7319989B2 (ja) 2023-08-02
WO2019090222A1 (fr) 2019-05-09
US10946022B2 (en) 2021-03-16
US20200022982A1 (en) 2020-01-23

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