MA49153A - Éléments régulateurs à haute activité - Google Patents
Éléments régulateurs à haute activitéInfo
- Publication number
- MA49153A MA49153A MA049153A MA49153A MA49153A MA 49153 A MA49153 A MA 49153A MA 049153 A MA049153 A MA 049153A MA 49153 A MA49153 A MA 49153A MA 49153 A MA49153 A MA 49153A
- Authority
- MA
- Morocco
- Prior art keywords
- regulatory elements
- high activity
- activity regulatory
- elements
- regulatory
- Prior art date
Links
- 230000000694 effects Effects 0.000 title 1
- 230000001105 regulatory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0381—Animal model for diseases of the hematopoietic system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14142—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762508968P | 2017-05-19 | 2017-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA49153A true MA49153A (fr) | 2021-03-24 |
Family
ID=64274721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA049153A MA49153A (fr) | 2017-05-19 | 2018-05-18 | Éléments régulateurs à haute activité |
Country Status (11)
Country | Link |
---|---|
US (1) | US20200231943A1 (fr) |
EP (1) | EP3624858A4 (fr) |
JP (3) | JP7315475B2 (fr) |
KR (2) | KR20240024326A (fr) |
CN (1) | CN110944674A (fr) |
AU (1) | AU2018269050A1 (fr) |
BR (1) | BR112019024222A2 (fr) |
CA (1) | CA3063464A1 (fr) |
MA (1) | MA49153A (fr) |
TW (1) | TWI811219B (fr) |
WO (1) | WO2018213786A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201420139D0 (en) | 2014-11-12 | 2014-12-24 | Ucl Business Plc | Factor IX gene therapy |
US10842885B2 (en) | 2018-08-20 | 2020-11-24 | Ucl Business Ltd | Factor IX encoding nucleotides |
MA55625A (fr) * | 2019-04-12 | 2022-02-16 | Encoded Therapeutics Inc | Compositions et méthodes d'administration de produits thérapeutiques |
WO2021016075A1 (fr) | 2019-07-19 | 2021-01-28 | Flagship Pioneering Innovations Vi, Llc | Compositions à recombinase et leurs méthodes d'utilisation |
IL294781A (en) * | 2020-02-14 | 2022-09-01 | Ultragenyx Pharmaceutical Inc | Gene therapy for the treatment of cdkl5-deficient disorder |
KR20240045203A (ko) * | 2021-08-05 | 2024-04-05 | 인스메드 인코포레이티드 | 아데노-연관 바이러스 입자 및 이의 사용 방법 |
WO2024079661A1 (fr) * | 2022-10-11 | 2024-04-18 | Meiragtx Uk Ii Limited | Thérapie génique atp7b |
CN117925624B (zh) * | 2024-03-22 | 2024-05-31 | 上海凌医生物科技有限公司 | 一种金属响应调控元件 |
CN117947035A (zh) * | 2024-03-25 | 2024-04-30 | 上海凌医生物科技有限公司 | 一种增强基因表达的启动子 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1232276B8 (fr) * | 1999-11-16 | 2007-06-27 | Genzyme Corporation | Vecteurs et transgenes ayant des elements regulateurs pour l'administration de genes dans le foie |
US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
EP1783645A1 (fr) * | 2005-11-08 | 2007-05-09 | Actigenics | Procédes pour identifier des molécules de micro-arn et leurs applications dans la recherche et la santé humaine |
EP2097538A4 (fr) * | 2006-12-07 | 2011-11-30 | Switchgear Genomics | Eléments de régulation transcriptionnelle de voies biologiques, outils, et procédés |
WO2013033627A2 (fr) * | 2011-09-01 | 2013-03-07 | The Regents Of The University Of California | Diagnostic et traitement de l'arthrite à l'aide de l'épigénétique |
CN104520428B (zh) * | 2012-02-17 | 2018-09-21 | 费城儿童医院 | 将基因转移到细胞、器官和组织的aav载体组合物和方法 |
MX2017007965A (es) * | 2014-12-17 | 2018-01-18 | Fundacion Para La Investig Medica Aplicada | Construcciones de acido nucleico y vectores de terapia de genes para uso en el tratamiento de enfermedad de wilson. |
TWI707951B (zh) * | 2015-04-08 | 2020-10-21 | 美商健臻公司 | 過大腺相關載體之製造 |
MA50942A (fr) * | 2017-12-01 | 2020-10-07 | Encoded Therapeutics Inc | Protéines de liaison à l'adn modifiées |
EA202192376A1 (ru) * | 2019-02-28 | 2021-12-27 | Инкоудид Терапьютикс, Инк. | Композиции и способы лечения ламинопатий |
-
2018
- 2018-05-18 JP JP2019563548A patent/JP7315475B2/ja active Active
- 2018-05-18 KR KR1020247004550A patent/KR20240024326A/ko active Application Filing
- 2018-05-18 TW TW107117128A patent/TWI811219B/zh active
- 2018-05-18 CN CN201880048355.4A patent/CN110944674A/zh active Pending
- 2018-05-18 WO PCT/US2018/033515 patent/WO2018213786A1/fr unknown
- 2018-05-18 AU AU2018269050A patent/AU2018269050A1/en active Pending
- 2018-05-18 CA CA3063464A patent/CA3063464A1/fr active Pending
- 2018-05-18 MA MA049153A patent/MA49153A/fr unknown
- 2018-05-18 BR BR112019024222-8A patent/BR112019024222A2/pt unknown
- 2018-05-18 KR KR1020197037368A patent/KR102636351B1/ko active IP Right Grant
- 2018-05-18 EP EP18803184.3A patent/EP3624858A4/fr active Pending
-
2019
- 2019-11-18 US US16/687,426 patent/US20200231943A1/en active Pending
-
2022
- 2022-09-26 JP JP2022152422A patent/JP2022173348A/ja active Pending
-
2023
- 2023-12-14 JP JP2023211093A patent/JP2024015408A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BR112019024222A2 (pt) | 2020-08-18 |
JP2024015408A (ja) | 2024-02-01 |
TWI811219B (zh) | 2023-08-11 |
KR20240024326A (ko) | 2024-02-23 |
EP3624858A1 (fr) | 2020-03-25 |
JP2022173348A (ja) | 2022-11-18 |
KR20200026814A (ko) | 2020-03-11 |
KR102636351B1 (ko) | 2024-02-15 |
CN110944674A (zh) | 2020-03-31 |
JP7315475B2 (ja) | 2023-07-26 |
EP3624858A4 (fr) | 2021-06-23 |
US20200231943A1 (en) | 2020-07-23 |
WO2018213786A1 (fr) | 2018-11-22 |
JP2020520643A (ja) | 2020-07-16 |
TW201903152A (zh) | 2019-01-16 |
CA3063464A1 (fr) | 2018-11-22 |
AU2018269050A1 (en) | 2020-01-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA49153A (fr) | Éléments régulateurs à haute activité | |
DK3240773T3 (da) | Picolinamidforbindelser med fungicid aktivitet | |
BR112017020873A2 (pt) | misturas herbicidas | |
FI20155792A (fi) | Kapasiteettisuunnittelumenetelmä | |
UA33302S (uk) | Диск для борони | |
MA53566A (fr) | Cartouche | |
TWI799481B (zh) | 封阻型異氰酸酯 | |
DK3619201T3 (da) | Herbicidvirksomme 4-difluormethylbenzoylamider | |
BR112017017193A2 (pt) | compostos herbicidas | |
MA50913A (fr) | Nouvelles combinaisons de défoliants | |
BR112017023150A2 (pt) | compostos herbicidas. | |
FI20165709A (fi) | Aktiviteetin intensiteettitason määrittäminen | |
DK3487491T3 (da) | Sammensætninger til forbedring af hjerneaktivitet | |
DK3277807T3 (da) | Eukaryotiske ekspressionsvektorer, der omfatter regulatoriske elementer af globin-genklynger | |
DK3373621T3 (da) | Roamingløsning | |
DK3391047T3 (da) | T-cellereaktivitetsplatform | |
KR20180084912A (ko) | 시계 밴드 | |
IT201700079483A1 (it) | Struttura di letto per degenza | |
IT201600132658A1 (it) | Impianto di caricamento mobile per betoniere | |
MA45974A (fr) | Produit à activité anti-stress, anxiolytique et antidépressante et composition à base de ce produit | |
BR112017022810A2 (pt) | compostos herbicidas. | |
BR112017022809A2 (pt) | compostos herbicidas. | |
ES2974251T3 (es) | Cápsula dosificadora | |
DK3296383T3 (da) | Humlepellets | |
IT201700050203A1 (it) | Termostato di protezione per bruciatori |