MA49130A - Nouvelles particules de support pour des formulations de poudre sèche pour l'inhalation - Google Patents

Nouvelles particules de support pour des formulations de poudre sèche pour l'inhalation

Info

Publication number
MA49130A
MA49130A MA049130A MA49130A MA49130A MA 49130 A MA49130 A MA 49130A MA 049130 A MA049130 A MA 049130A MA 49130 A MA49130 A MA 49130A MA 49130 A MA49130 A MA 49130A
Authority
MA
Morocco
Prior art keywords
inhalation
dry powder
carrier particles
powder formulations
new carrier
Prior art date
Application number
MA049130A
Other languages
English (en)
Inventor
Andrea Benassi
Ruggero Bettini
Francesca Buttini
Enrico Salomi
Francesca Schiaretti
Original Assignee
Chiesi Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farm Spa filed Critical Chiesi Farm Spa
Publication of MA49130A publication Critical patent/MA49130A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
MA049130A 2017-05-17 2018-05-16 Nouvelles particules de support pour des formulations de poudre sèche pour l'inhalation MA49130A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17171586 2017-05-17

Publications (1)

Publication Number Publication Date
MA49130A true MA49130A (fr) 2021-04-28

Family

ID=58715070

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049130A MA49130A (fr) 2017-05-17 2018-05-16 Nouvelles particules de support pour des formulations de poudre sèche pour l'inhalation

Country Status (10)

Country Link
US (2) US10583085B2 (fr)
EP (1) EP3624768A1 (fr)
KR (1) KR20200004816A (fr)
CN (1) CN110621299A (fr)
BR (1) BR112019024132A2 (fr)
CA (1) CA3060022A1 (fr)
MA (1) MA49130A (fr)
MX (1) MX2019013570A (fr)
RU (1) RU2745045C1 (fr)
WO (1) WO2018210909A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112870337A (zh) * 2021-01-26 2021-06-01 浙江科瑞特生物科技有限公司 一种血促性素和绒促性素复合激素冻干粉及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404945D0 (en) * 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
PT1158958E (pt) * 1999-03-05 2007-08-13 Chiesi Farma Spa ''composições farmacêuticas em pó, melhoradas, para inalação''
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
WO2003086358A1 (fr) 2002-04-12 2003-10-23 Campina Nederland Holding B.V. Excipient destine a des preparations d'inhalation de poudre seche
PT1658872E (pt) 2002-07-31 2011-05-12 Chiesi Farma Spa Inalador de p?
EP1610878B1 (fr) 2003-02-21 2014-09-03 University Of Bath Procede de production de particules
JO3102B1 (ar) * 2004-03-17 2017-09-20 Chiesi Framaceutici S P A صيغ صيدلانية لوسائل استنشاق بها مسحوق جاف تشتمل على مكون فعال بقوة منخفضة الجرعة
JP5173431B2 (ja) * 2004-12-22 2013-04-03 キャンピナ・ネダーランド・ホールディング・ビー.ブイ. 無水ラクトース凝集物およびその製造
GB0705159D0 (en) 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) 2007-06-18 2007-07-25 Prosonix Ltd Process
MX2011000405A (es) 2008-07-18 2011-03-04 Prosonix Ltd Proceso para mejorar la cristalinidad.
WO2011120779A1 (fr) * 2010-04-01 2011-10-06 Chiesi Farmaceutici S.P.A. Procédé de préparation de particules d'excipient pour poudres sèches à inhaler
EP2560611B1 (fr) * 2010-04-21 2018-01-03 Chiesi Farmaceutici S.p.A. Procédé de préparation de particules ayant des charges électrostatiques réduites
MA34449B1 (fr) * 2010-08-03 2013-08-01 Chiesi Farma Spa Formulation de poudre seche comprenant un inhibiteur de phosphodiesterase

Also Published As

Publication number Publication date
US20180333359A1 (en) 2018-11-22
EP3624768A1 (fr) 2020-03-25
KR20200004816A (ko) 2020-01-14
CN110621299A (zh) 2019-12-27
US10583085B2 (en) 2020-03-10
CA3060022A1 (fr) 2018-11-22
US20200163883A1 (en) 2020-05-28
BR112019024132A2 (pt) 2020-06-02
MX2019013570A (es) 2019-12-18
RU2745045C1 (ru) 2021-03-18
WO2018210909A1 (fr) 2018-11-22
US10709666B2 (en) 2020-07-14

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