MA49017A - Modulateurs du récepteur 7 de la 5-hydroxytryptamine et utilisation de ces derniers en tant qu'agents thérapeutiques - Google Patents

Modulateurs du récepteur 7 de la 5-hydroxytryptamine et utilisation de ces derniers en tant qu'agents thérapeutiques

Info

Publication number
MA49017A
MA49017A MA049017A MA49017A MA49017A MA 49017 A MA49017 A MA 49017A MA 049017 A MA049017 A MA 049017A MA 49017 A MA49017 A MA 49017A MA 49017 A MA49017 A MA 49017A
Authority
MA
Morocco
Prior art keywords
modulators
therapeutic agents
hydroxytryptamine receptor
hydroxytryptamine
receptor
Prior art date
Application number
MA049017A
Other languages
English (en)
French (fr)
Inventor
Benjamin E Blass
Kevin M Blattner
Daniel J Canney
Original Assignee
Univ Temple
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Temple filed Critical Univ Temple
Publication of MA49017A publication Critical patent/MA49017A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA049017A 2017-03-21 2018-03-15 Modulateurs du récepteur 7 de la 5-hydroxytryptamine et utilisation de ces derniers en tant qu'agents thérapeutiques MA49017A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762474280P 2017-03-21 2017-03-21

Publications (1)

Publication Number Publication Date
MA49017A true MA49017A (fr) 2020-02-05

Family

ID=63585688

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049017A MA49017A (fr) 2017-03-21 2018-03-15 Modulateurs du récepteur 7 de la 5-hydroxytryptamine et utilisation de ces derniers en tant qu'agents thérapeutiques

Country Status (5)

Country Link
US (3) US11220505B2 (https=)
EP (1) EP3600289A4 (https=)
JP (2) JP7365238B2 (https=)
MA (1) MA49017A (https=)
WO (1) WO2018175190A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014164756A1 (en) 2013-03-11 2014-10-09 Temple University Of The Commonwealth System Of Higher Education Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use
WO2016040554A1 (en) 2014-09-10 2016-03-17 Temple University-Of The Commonwealth System Of Higher Education Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use
IL309982A (en) 2016-11-15 2024-03-01 Univ Temple New modulators of 5-hydroxytryptamine receptor 7 and a method of using them
MA49019A (fr) 2017-03-21 2020-02-05 Univ Temple Nouveaux modulateurs du récepteur sigma 2 et leur procédé d'utilisation
JP7365238B2 (ja) 2017-03-21 2023-10-19 テンプル・ユニバーシティ－オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション ５－ヒドロキシトリプタミン受容体７調節物質および治療剤としてのその使用
EA202092328A1 (ru) * 2018-05-11 2021-04-08 Темпл Юниверсити-Оф Зэ Коммонвелс Систем Оф Хаер Эдьюкейшн Новые функционализированные лактамы в качестве модуляторов 5-гидрокситриптаминового рецептора 7 и способ их применения
GB201809295D0 (en) * 2018-06-06 2018-07-25 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
CN112010859B (zh) * 2019-05-30 2022-07-19 中国科学院上海药物研究所 一种并环化合物、其制备方法和用途
CA3160801A1 (en) * 2019-11-13 2021-05-20 Temple University-Of The Commonwealth System Of Higher Education Novel functionalized lactams as modulators of the 5-hydroxytryptamine receptor 7 and their method of use

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2514656A1 (en) 2003-01-31 2004-08-12 Pfizer Products Inc. 5ht7 antagonists and inverse agonists
US7435830B2 (en) 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
GB0419192D0 (en) * 2004-08-27 2004-09-29 Merck Sharp & Dohme Therapeutic agents
EP1875899A1 (en) 2006-06-29 2008-01-09 Laboratorios Del Dr. Esteve, S.A. Use of 5HT7 receptor agonists for the treatment of pain
CA2669447A1 (en) 2006-11-13 2008-05-29 King Pharmaceuticals Research And Development, Inc. Allosteric modulators of the a1 adenosine receptor
EP2201002B1 (en) 2007-10-12 2012-03-07 Eli Lilly And Company 5-ht7 receptor antagonists
US8148408B2 (en) 2008-05-09 2012-04-03 Abbott Laboratories Selective substituted pyridine ligands for neuronal nicotinic receptors
US20100069390A1 (en) 2008-09-05 2010-03-18 Supernus Pharmaceuticals, Inc. Method of treatment of attention deficit/hyperactivity disorder (ADHD)
CA2816551A1 (en) 2010-11-03 2012-05-10 Mcmaster University Method of treating mucosal inflammation
US8697888B2 (en) 2012-01-06 2014-04-15 Vanderbilt University Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors
US9464062B2 (en) 2012-11-28 2016-10-11 Temple University—Of the Commonwealth System of Higher Education Disubstituted oxazolidin-2-ones 5-hydroxytryptamine receptor 2B activity modulators
EP2928474B1 (en) 2012-12-07 2018-11-14 ChemoCentryx, Inc. Diazole lactams
WO2014164756A1 (en) 2013-03-11 2014-10-09 Temple University Of The Commonwealth System Of Higher Education Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use
MX2016008130A (es) 2013-12-20 2016-10-13 Esteve Labor Dr Derivados de piperidina con actividad multimodal contra el dolor.
WO2016040554A1 (en) 2014-09-10 2016-03-17 Temple University-Of The Commonwealth System Of Higher Education Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use
AR103297A1 (es) 2014-12-30 2017-05-03 Forma Therapeutics Inc Pirrolo y pirazolopirimidinas como inhibidores de la proteasa 7 específica de ubiquitina
WO2016183150A1 (en) 2015-05-12 2016-11-17 Temple University-Of The Commonwealth System Of Higher Education Novel sigma-2 receptor binders and their method of use
IL309982A (en) 2016-11-15 2024-03-01 Univ Temple New modulators of 5-hydroxytryptamine receptor 7 and a method of using them
MA49019A (fr) 2017-03-21 2020-02-05 Univ Temple Nouveaux modulateurs du récepteur sigma 2 et leur procédé d'utilisation
JP7365238B2 (ja) * 2017-03-21 2023-10-19 テンプル・ユニバーシティ－オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション ５－ヒドロキシトリプタミン受容体７調節物質および治療剤としてのその使用
EA202092328A1 (ru) 2018-05-11 2021-04-08 Темпл Юниверсити-Оф Зэ Коммонвелс Систем Оф Хаер Эдьюкейшн Новые функционализированные лактамы в качестве модуляторов 5-гидрокситриптаминового рецептора 7 и способ их применения

Also Published As

Publication number Publication date
JP2020511515A (ja) 2020-04-16
US20200331915A1 (en) 2020-10-22
US20240300953A1 (en) 2024-09-12
US11220505B2 (en) 2022-01-11
JP2023168626A (ja) 2023-11-24
WO2018175190A1 (en) 2018-09-27
EP3600289A1 (en) 2020-02-05
JP7365238B2 (ja) 2023-10-19
US12338245B2 (en) 2025-06-24
EP3600289A4 (en) 2020-08-05
US11807642B2 (en) 2023-11-07
JP7705909B2 (ja) 2025-07-10
US20220348581A1 (en) 2022-11-03

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