MA39089A1 - Procédé permettant de préparer des compositions d'inhalation de poudre sèche - Google Patents
Procédé permettant de préparer des compositions d'inhalation de poudre sècheInfo
- Publication number
- MA39089A1 MA39089A1 MA39089A MA39089A MA39089A1 MA 39089 A1 MA39089 A1 MA 39089A1 MA 39089 A MA39089 A MA 39089A MA 39089 A MA39089 A MA 39089A MA 39089 A1 MA39089 A1 MA 39089A1
- Authority
- MA
- Morocco
- Prior art keywords
- active ingredient
- dry powder
- powder inhalation
- excipient
- preparing dry
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention porte sur un procédé permettant de préparer des compositions d'inhalation de poudre sèche qui comprennent au moins deux ingrédients actifs et un excipient de particule inerte, et sur un procédé permettant de réguler la performance de telles compositions. Le procédé consiste à mélanger le premier ingrédient actif et une partie du second ingrédient actif avec un premier excipient pour obtenir un premier prémélange, à mélanger la partie restante du second ingrédient actif avec un second excipient pour obtenir un second prémélange et, finalement, à mélanger les premier et second prémélanges l'un avec l'autre, les grades des deux excipients présentant une taille particulaire médiane différente. Le niveau fpd du second ingrédient actif peut être ajusté simplement par modification de la proportion selon laquelle il a été divisé entre le premier et le second excipient.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361913024P | 2013-12-06 | 2013-12-06 | |
PCT/FI2014/000038 WO2015082756A1 (fr) | 2013-12-06 | 2014-12-05 | Procédé permettant de préparer des compositions d'inhalation de poudre sèche |
Publications (2)
Publication Number | Publication Date |
---|---|
MA39089A1 true MA39089A1 (fr) | 2017-10-31 |
MA39089B1 MA39089B1 (fr) | 2019-03-29 |
Family
ID=52146529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA39089A MA39089B1 (fr) | 2013-12-06 | 2014-12-05 | Procédé permettant de préparer des compositions d'inhalation de poudre sèche |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP3076957B1 (fr) |
JP (1) | JP6353049B2 (fr) |
KR (1) | KR102255402B1 (fr) |
CN (2) | CN105873575A (fr) |
AU (1) | AU2014359111B2 (fr) |
BR (1) | BR112016012871B1 (fr) |
CA (1) | CA2928695C (fr) |
CL (1) | CL2016001359A1 (fr) |
CY (1) | CY1122797T1 (fr) |
DK (1) | DK3076957T3 (fr) |
EA (1) | EA033247B1 (fr) |
ES (1) | ES2776350T3 (fr) |
HR (1) | HRP20200618T1 (fr) |
HU (1) | HUE049162T2 (fr) |
LT (1) | LT3076957T (fr) |
MA (1) | MA39089B1 (fr) |
MX (1) | MX368857B (fr) |
MY (1) | MY185073A (fr) |
PH (1) | PH12016501045A1 (fr) |
PL (1) | PL3076957T3 (fr) |
PT (1) | PT3076957T (fr) |
SA (1) | SA516371266B1 (fr) |
SI (1) | SI3076957T1 (fr) |
UA (1) | UA118861C2 (fr) |
WO (1) | WO2015082756A1 (fr) |
ZA (1) | ZA201602909B (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3082692A1 (fr) * | 2013-12-20 | 2016-10-26 | The Procter & Gamble Company | Couche avec manchons et ajustement améliorés |
WO2024010539A1 (fr) * | 2022-07-07 | 2024-01-11 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Procédé de préparation de compositions de poudre sèche pour inhalation à l'aide de différents mélangeurs |
CN115364075B (zh) * | 2022-09-16 | 2023-11-10 | 苏州易合医药有限公司 | 一种吸入颗粒组合物及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4140689B4 (de) * | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalationspulver und Verfahren zu ihrer Herstellung |
US6369115B1 (en) * | 2000-03-20 | 2002-04-09 | Dura Pharmaceuticals, Inc. | Stabilized powder formulations |
GB0012260D0 (en) * | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel composition |
EP1487417A4 (fr) * | 2001-09-17 | 2010-03-17 | Glaxo Group Ltd | Formulations de medicament en poudre seche |
JP3691459B2 (ja) * | 2002-06-14 | 2005-09-07 | 久光メディカル株式会社 | 粉末状吸入剤組成物 |
GB0219512D0 (en) * | 2002-08-21 | 2002-10-02 | Norton Healthcare Ltd | Inhalation compositions with high drug ratios |
JP4744876B2 (ja) * | 2002-08-21 | 2011-08-10 | ノートン・ヘルスケアー リミテッド | 乾燥粉末吸入組成物の製造方法 |
GB0714134D0 (en) * | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
EP2221048A1 (fr) * | 2009-02-18 | 2010-08-25 | Siegfried Generics International AG | Compositions pharmaceutiques pour l'inhalation |
EP2571486A4 (fr) * | 2010-05-20 | 2013-12-04 | Sun Pharma Advanced Res Co Ltd | Composition d'inhalation à poudre sèche |
EP3412277B1 (fr) * | 2012-01-25 | 2022-12-14 | Chiesi Farmaceutici S.p.A. | Formulation de poudre sèche comprenant un corticostéroïde et un médicament béta-adrénergique pour l'administration par inhalation |
-
2014
- 2014-05-12 UA UAA201607280A patent/UA118861C2/uk unknown
- 2014-12-05 ES ES14819038T patent/ES2776350T3/es active Active
- 2014-12-05 KR KR1020167018061A patent/KR102255402B1/ko active IP Right Grant
- 2014-12-05 PT PT148190382T patent/PT3076957T/pt unknown
- 2014-12-05 BR BR112016012871-0A patent/BR112016012871B1/pt active IP Right Grant
- 2014-12-05 EP EP14819038.2A patent/EP3076957B1/fr active Active
- 2014-12-05 WO PCT/FI2014/000038 patent/WO2015082756A1/fr active Application Filing
- 2014-12-05 LT LTEP14819038.2T patent/LT3076957T/lt unknown
- 2014-12-05 MA MA39089A patent/MA39089B1/fr unknown
- 2014-12-05 AU AU2014359111A patent/AU2014359111B2/en active Active
- 2014-12-05 SI SI201431510T patent/SI3076957T1/sl unknown
- 2014-12-05 CN CN201480065585.3A patent/CN105873575A/zh active Pending
- 2014-12-05 HU HUE14819038A patent/HUE049162T2/hu unknown
- 2014-12-05 CN CN202111212611.9A patent/CN113908142A/zh active Pending
- 2014-12-05 EA EA201691181A patent/EA033247B1/ru not_active IP Right Cessation
- 2014-12-05 CA CA2928695A patent/CA2928695C/fr active Active
- 2014-12-05 DK DK14819038.2T patent/DK3076957T3/da active
- 2014-12-05 PL PL14819038T patent/PL3076957T3/pl unknown
- 2014-12-05 MX MX2016007266A patent/MX368857B/es active IP Right Grant
- 2014-12-05 JP JP2016536546A patent/JP6353049B2/ja active Active
- 2014-12-05 MY MYPI2016702020A patent/MY185073A/en unknown
-
2016
- 2016-04-29 ZA ZA2016/02909A patent/ZA201602909B/en unknown
- 2016-06-02 PH PH12016501045A patent/PH12016501045A1/en unknown
- 2016-06-03 CL CL2016001359A patent/CL2016001359A1/es unknown
- 2016-06-05 SA SA516371266A patent/SA516371266B1/ar unknown
-
2020
- 2020-04-13 CY CY20201100340T patent/CY1122797T1/el unknown
- 2020-04-20 HR HRP20200618TT patent/HRP20200618T1/hr unknown
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