MA31795B1 - Molécules et méthodes pour moduler un constituant de complément - Google Patents
Molécules et méthodes pour moduler un constituant de complémentInfo
- Publication number
- MA31795B1 MA31795B1 MA32801A MA32801A MA31795B1 MA 31795 B1 MA31795 B1 MA 31795B1 MA 32801 A MA32801 A MA 32801A MA 32801 A MA32801 A MA 32801A MA 31795 B1 MA31795 B1 MA 31795B1
- Authority
- MA
- Morocco
- Prior art keywords
- methods
- particles
- modification
- supplement component
- supplement
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 239000013589 supplement Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
L'invention concerne des compositions se liant aux épitopes c3b ainsi que des méthodes d'utilisation de ces compositions.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98495107P | 2007-11-02 | 2007-11-02 | |
PCT/EP2008/064809 WO2009056631A2 (fr) | 2007-11-02 | 2008-10-31 | Molécules et méthodes pour moduler un constituant de complément |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31795B1 true MA31795B1 (fr) | 2010-10-01 |
Family
ID=40343498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32801A MA31795B1 (fr) | 2007-11-02 | 2010-04-30 | Molécules et méthodes pour moduler un constituant de complément |
Country Status (21)
Country | Link |
---|---|
US (1) | US20090175875A1 (fr) |
EP (1) | EP2207807A2 (fr) |
JP (1) | JP2011503024A (fr) |
KR (1) | KR20100067681A (fr) |
CN (1) | CN101848937A (fr) |
AR (1) | AR069130A1 (fr) |
AU (1) | AU2008320820A1 (fr) |
CA (1) | CA2703911A1 (fr) |
CL (1) | CL2008003241A1 (fr) |
CO (1) | CO6270341A2 (fr) |
CR (1) | CR11361A (fr) |
EA (1) | EA201000717A1 (fr) |
IL (1) | IL204722A0 (fr) |
MA (1) | MA31795B1 (fr) |
MX (1) | MX2010004833A (fr) |
PE (1) | PE20091388A1 (fr) |
SV (1) | SV2010003556A (fr) |
TN (1) | TN2010000169A1 (fr) |
TW (1) | TW200924795A (fr) |
WO (1) | WO2009056631A2 (fr) |
ZA (1) | ZA201002335B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2044111E (pt) | 2006-06-21 | 2014-11-12 | Univ Colorado Regents | Abordagem seletiva do fator h do complemento para o tratamento de doenças |
US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
US8680019B2 (en) * | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
US20090176654A1 (en) * | 2007-08-10 | 2009-07-09 | Protelix, Inc. | Universal fibronectin type III binding-domain libraries |
DK2207808T3 (da) | 2007-11-02 | 2013-08-05 | Novartis Ag | Forbedrede Nogo-A-bindingsmolekyler samt deres farmaceutiske anvendelse |
US20100291106A1 (en) * | 2009-05-06 | 2010-11-18 | Novartis Ag | Compositions and methods for antibodies targeting complement protein c3b |
AU2010266127B2 (en) | 2009-07-02 | 2015-11-05 | Musc Foundation For Research Development | Methods of stimulating liver regeneration |
KR20120130748A (ko) | 2009-11-05 | 2012-12-03 | 알렉시온 캠브리지 코포레이션 | 발작성 야간 혈색소뇨증, 용혈성 빈혈, 및 혈관내 및 혈관외 용혈을 수반한 질환 상태의 치료 |
EP2569332B1 (fr) | 2010-05-14 | 2019-01-09 | The Regents of the University of Colorado, A Body Corporate | Groupes de ciblage des récepteurs 2 du complément (cr2) améliorés |
CA2803588A1 (fr) | 2010-06-22 | 2011-12-29 | The Regents Of The University Of Colorado, A Body Corporate | Anticorps contre le fragment c3d du composant 3 du complement |
CA2821067C (fr) * | 2010-11-29 | 2019-06-04 | Novelmed Therapeutics, Inc. | Neoanticorps pour le diagnostic d'une lesion tissulaire |
US10413620B2 (en) | 2012-08-17 | 2019-09-17 | The Regents Of The University Of Colorado, A Body Corporate | Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging |
AU2013302441B2 (en) | 2012-08-17 | 2018-05-10 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for detecting complement activation |
CN105683759B (zh) | 2013-08-07 | 2019-03-29 | 瑞颂医药公司 | 非典型溶血性尿毒综合征(aHUS)生物标志物蛋白 |
EP3092252B1 (fr) * | 2014-01-08 | 2019-09-18 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Anticorps ciblant une protéine c3d du complément déposée sur une surface cellulaire, et utilisation de celui-ci |
US10568568B2 (en) * | 2014-08-27 | 2020-02-25 | Capnia, Inc. | Methods for immune globulin administration |
CA3009393C (fr) * | 2015-12-23 | 2023-08-22 | Greenovation Biotech Gmbh | Polypeptides pour l'inhibition de l'activation du complement |
AU2017283470B2 (en) | 2016-06-14 | 2024-03-21 | Regeneron Pharmaceuticals, Inc. | Anti-C5 antibodies and uses thereof |
EP3526248A4 (fr) | 2016-10-17 | 2020-07-08 | Musc Foundation for Research Development | Compositions et méthodes de traitement d'une lésion du système nerveux central |
JP2021506241A (ja) | 2017-12-13 | 2021-02-22 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | 抗c5抗体組み合わせ物およびその使用 |
GB201800620D0 (en) * | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
GB2583560A (en) | 2018-12-11 | 2020-11-04 | Admirx Inc | Fusion protein constructs for complement associated disease |
CN111171147B (zh) * | 2020-02-11 | 2021-07-20 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c3分子的全人源单克隆抗体及应用 |
US20240132617A1 (en) * | 2022-09-20 | 2024-04-25 | Visterra, Inc. | Treatment of complement mediated diseases and disorders with c3b antibodies |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE452065B (sv) * | 1986-04-11 | 1987-11-09 | Ulf R Nilsson | Antikroppspreparation vars antikroppar er specifika for determinanter i c3 b regionen hos denaturerat humant c3 samt dess anvendning och framstellning |
US5932217A (en) * | 1991-05-03 | 1999-08-03 | The Rockefeller University | Peptides which inhibit adhesion between leukocytes and endothelial cells |
WO1997001578A1 (fr) * | 1995-06-29 | 1997-01-16 | Medical Biology Institute | Procede d'identification des peptides qui affectent les interactions proteine-proteine et des peptides modulant l'activite complementaire |
EP1384079A2 (fr) * | 2001-05-02 | 2004-01-28 | Oxford GlycoSciences (UK) Limited | Proteines, genes et leur utilisation dans le cadre du diagnostic et du traitement du cancer du sein |
US7042716B2 (en) * | 2003-08-25 | 2006-05-09 | Simon John Edward Shearman | Ergonomic pull-out computer housing |
US20090004183A1 (en) * | 2004-07-23 | 2009-01-01 | Taylor Ronald P | Compositions and Methods for Regulating the Alternative Pathway of Complement |
WO2006042252A2 (fr) * | 2004-10-08 | 2006-04-20 | Potentia Pharmeceuticals, Inc. | Proteines regulatrices du complement viral pour troubles de la vue |
WO2007047796A2 (fr) * | 2005-10-17 | 2007-04-26 | Institute For Systems Biology | Glycoproteines derivees de tissus et du serum et leurs methodes d'utilisation |
US7327547B1 (en) * | 2006-01-20 | 2008-02-05 | Epstein Barry M | Circuit element and use thereof |
KR20150029002A (ko) * | 2007-06-07 | 2015-03-17 | 제넨테크, 인크. | 보체-관련 장애의 예방 및 치료를 위한 C3b 항체 및 방법 |
-
2008
- 2008-10-30 AR ARP080104764A patent/AR069130A1/es unknown
- 2008-10-30 PE PE2008001860A patent/PE20091388A1/es not_active Application Discontinuation
- 2008-10-30 CL CL2008003241A patent/CL2008003241A1/es unknown
- 2008-10-31 MX MX2010004833A patent/MX2010004833A/es not_active Application Discontinuation
- 2008-10-31 EA EA201000717A patent/EA201000717A1/ru unknown
- 2008-10-31 CN CN200880114277A patent/CN101848937A/zh active Pending
- 2008-10-31 CA CA2703911A patent/CA2703911A1/fr not_active Abandoned
- 2008-10-31 AU AU2008320820A patent/AU2008320820A1/en not_active Abandoned
- 2008-10-31 EP EP08844727A patent/EP2207807A2/fr not_active Withdrawn
- 2008-10-31 TW TW097142274A patent/TW200924795A/zh unknown
- 2008-10-31 JP JP2010532555A patent/JP2011503024A/ja active Pending
- 2008-10-31 KR KR1020107009602A patent/KR20100067681A/ko not_active Application Discontinuation
- 2008-10-31 WO PCT/EP2008/064809 patent/WO2009056631A2/fr active Application Filing
- 2008-11-03 US US12/263,909 patent/US20090175875A1/en not_active Abandoned
-
2010
- 2010-03-25 IL IL204722A patent/IL204722A0/en unknown
- 2010-04-01 ZA ZA2010/02335A patent/ZA201002335B/en unknown
- 2010-04-09 CR CR11361A patent/CR11361A/es not_active Application Discontinuation
- 2010-04-16 TN TN2010000169A patent/TN2010000169A1/fr unknown
- 2010-04-28 CO CO10050312A patent/CO6270341A2/es not_active Application Discontinuation
- 2010-04-30 SV SV2010003556A patent/SV2010003556A/es not_active Application Discontinuation
- 2010-04-30 MA MA32801A patent/MA31795B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
IL204722A0 (en) | 2010-11-30 |
TW200924795A (en) | 2009-06-16 |
AU2008320820A1 (en) | 2009-05-07 |
WO2009056631A3 (fr) | 2009-08-20 |
KR20100067681A (ko) | 2010-06-21 |
MX2010004833A (es) | 2010-05-27 |
SV2010003556A (es) | 2011-03-23 |
CL2008003241A1 (es) | 2009-07-31 |
PE20091388A1 (es) | 2009-09-24 |
EP2207807A2 (fr) | 2010-07-21 |
US20090175875A1 (en) | 2009-07-09 |
ZA201002335B (en) | 2011-02-23 |
CA2703911A1 (fr) | 2009-05-07 |
EA201000717A1 (ru) | 2010-12-30 |
WO2009056631A2 (fr) | 2009-05-07 |
CR11361A (es) | 2010-06-01 |
JP2011503024A (ja) | 2011-01-27 |
CN101848937A (zh) | 2010-09-29 |
TN2010000169A1 (en) | 2011-11-11 |
AR069130A1 (es) | 2009-12-30 |
CO6270341A2 (es) | 2011-04-20 |
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