MA23818A1 - Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue - Google Patents

Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue

Info

Publication number
MA23818A1
MA23818A1 MA24175A MA24175A MA23818A1 MA 23818 A1 MA23818 A1 MA 23818A1 MA 24175 A MA24175 A MA 24175A MA 24175 A MA24175 A MA 24175A MA 23818 A1 MA23818 A1 MA 23818A1
Authority
MA
Morocco
Prior art keywords
subtilin
carlsberg
variants
reduced absorption
increased hydrolysis
Prior art date
Application number
MA24175A
Other languages
English (en)
Inventor
Nelton Rubingh Donn
Brode Phf Iii
Lee Barnett Robby
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MA23818A1 publication Critical patent/MA23818A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MA24175A 1995-03-08 1996-03-07 Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue MA23818A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/400,698 US6455295B1 (en) 1995-03-08 1995-03-08 Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis

Publications (1)

Publication Number Publication Date
MA23818A1 true MA23818A1 (fr) 1996-10-01

Family

ID=23584644

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24175A MA23818A1 (fr) 1995-03-08 1996-03-07 Variants de subtilisine carlsberg ayant une absorption reduite et une hydrolyse accrue

Country Status (14)

Country Link
US (1) US6455295B1 (fr)
EP (1) EP0813596A2 (fr)
JP (1) JPH11501812A (fr)
CN (1) CN1183119A (fr)
AU (1) AU4868896A (fr)
BR (1) BR9607356A (fr)
CA (1) CA2214348C (fr)
CZ (1) CZ279397A3 (fr)
HU (1) HUP9800765A3 (fr)
IL (1) IL117266A0 (fr)
MA (1) MA23818A1 (fr)
MX (1) MX9706851A (fr)
WO (1) WO1996028566A2 (fr)
ZA (1) ZA961631B (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
US6300116B1 (en) * 1996-11-04 2001-10-09 Novozymes A/S Modified protease having improved autoproteolytic stability
JPH10204500A (ja) * 1997-01-20 1998-08-04 Soft Kyukyu Corp:Kk 発泡錠剤洗浄剤
EP0913458B1 (fr) * 1997-10-22 2004-06-16 The Procter & Gamble Company Compositions détergentes liquide pour surfaces dures
MA24811A1 (fr) 1997-10-23 1999-12-31 Procter & Gamble Compositions de lavage contenant des variantes de proteases multisubstituees
ES2367505T3 (es) * 1997-10-23 2011-11-04 Danisco Us Inc. Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes.
US6773907B2 (en) 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6780629B2 (en) 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
KR100762164B1 (ko) * 1997-11-21 2007-10-01 노보자임스 에이/에스 프로테아제 변이체 및 조성물
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6831053B1 (en) 1998-10-23 2004-12-14 The Procter & Gamble Company Bleaching compositions comprising multiply-substituted protease variants
KR100660799B1 (ko) * 1998-12-18 2006-12-26 노보자임스 에이/에스 활성부위 루프 영역에 추가적 아미노산 잔기를 가지는서브그룹 ｉ-ｓ１과 ｉ-ｓ２의 서브틸라제 효소
KR100649899B1 (ko) * 1998-12-18 2006-11-24 노보자임스 에이/에스 활성부위 루프 영역에 추가적 아미노산 잔기를 가지는서브그룹 ｉ-ｓ１과 ｉ-ｓ２의 서브틸라제 효소
KR100660746B1 (ko) * 1998-12-18 2006-12-22 노보자임스 에이/에스 활성부위 루프 영역에 추가적 아미노산 잔기를 가지는서브그룹 ｉ-ｓ１과 ｉ-ｓ２의 서브틸라제 효소
BRPI9916349B1 (pt) * 1998-12-18 2017-04-25 Novozymes As enzima subtilase, composição, e, uso de uma subtilase ou de uma variante de subtilase ou de uma composição de enzima
KR100660818B1 (ko) * 1998-12-18 2006-12-26 노보자임스 에이/에스 활성부위 루프 영역에 추가적 아미노산 잔기를 가지는서브그룹 ｉ-ｓ１과 ｉ-ｓ２의 서브틸라제 효소
BRPI9916353B1 (pt) * 1998-12-18 2016-04-19 Novozymes As enzima de subtilase isolada, composição, e, uso de uma enzima subtilase isolada ou de uma composição de enzima
ATE371023T1 (de) * 1998-12-18 2007-09-15 Novozymes As Subtilase enzyme der i-s1 und i-s2 untergruppen mit einem zusätzlichen aminosaürerest in einer aktiven schleifenregion
WO2000037626A1 (fr) * 1998-12-18 2000-06-29 Novozymes A/S Enzymes subtilases des sous-groupes i-s1 et i-s2 ayant un residu d'acide amine additionnel dans une region boucle de site actif
DE10153792A1 (de) * 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
DE10260903A1 (de) * 2002-12-20 2004-07-08 Henkel Kgaa Neue Perhydrolasen
US7294499B2 (en) * 2003-01-30 2007-11-13 Novozymes A/S Subtilases
DE102004029475A1 (de) * 2004-06-18 2006-01-26 Henkel Kgaa Neues enzymatisches Bleichsystem
DE102007044415A1 (de) 2007-09-17 2009-03-19 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen
KR20110095254A (ko) * 2008-11-11 2011-08-24 다니스코 유에스 인크. 서브틸리신 변이체를 함유하는 조성물 및 방법
EP3294884B1 (fr) * 2015-05-13 2021-01-27 Danisco US Inc. Variants de protéase aprl-clade et leurs utilisations
DE102016204815A1 (de) * 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Proteasen mit verbesserte Enzymstabilität in Waschmittel
DE102016204814A1 (de) 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Verbesserte Reinigungsleistung an Protein sensitiven Anschmutzungen
DE102017215629A1 (de) 2017-09-05 2019-03-07 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasevarianten III
WO2023225459A2 (fr) 2022-05-14 2023-11-23 Novozymes A/S Compositions et procédés de prévention, de traitement, de suppression et/ou d'élimination d'infestations et d'infections phytopathogènes

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310675A (en) * 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
US4760025A (en) * 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5763257A (en) * 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
US5346823A (en) * 1984-05-29 1994-09-13 Genencor, Inc. Subtilisin modifications to enhance oxidative stability
US5182204A (en) * 1984-05-29 1993-01-26 Genencor International, Inc. Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors
US5371008A (en) * 1984-05-29 1994-12-06 Genencor International, Inc. Substrate assisted catalysis
US5155033A (en) * 1989-01-06 1992-10-13 Genencor, Inc. Subtilisins modified at position 225 resulting in a shift in catalytic activity
US5244791A (en) * 1984-05-29 1993-09-14 Genecor International, Inc. Methods of ester hydrolysis
US5972682A (en) * 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US5185258A (en) * 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
US5371190A (en) * 1984-05-29 1994-12-06 Genencor International, Inc. Substrate assisted catalysis
JP2599946B2 (ja) 1986-01-15 1997-04-16 アムジェン，インコーポレイテツド ズブチリシン類似体
US4908773A (en) 1987-04-06 1990-03-13 Genex Corporation Computer designed stabilized proteins and method for producing same
US5013657A (en) 1988-04-12 1991-05-07 Bryan Philip N Subtilisin mutations
US4980288A (en) 1986-02-12 1990-12-25 Genex Corporation Subtilisin with increased thermal stability
US4990452A (en) * 1986-02-12 1991-02-05 Genex Corporation Combining mutations for stabilization of subtilisin
EP0260299A4 (fr) 1986-02-12 1988-11-24 Genex Corp Procede de mutagenese et de criblage et produit obtenu.
US5240632A (en) * 1986-03-26 1993-08-31 Amway Corporation Machine dishwasher water spot control composition
ATE116365T1 (de) * 1986-04-30 1995-01-15 Genencor Int Mutante einer nicht menschlichen carbonyl- hydrolase, für diese kodierende dns-sequenzen und vektoren und durch diese vektoren transformierte wirte.
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
PT86864B (pt) * 1987-02-27 1992-05-29 Gist Brocades Nv Processo para clonagem molecular e expressao de genes que codificam para enzimas proteoliticas
US5260207A (en) * 1987-04-06 1993-11-09 Enzon Labs Inc. Engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins
ATE184316T1 (de) * 1987-04-06 1999-09-15 Novo Nordisk As Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen
US4914031A (en) * 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
PT89702B (pt) * 1988-02-11 1994-04-29 Gist Brocades Nv Processo para a preparacao de novos enzimas proteoliticos e de detergentes que os contem
US6287841B1 (en) * 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
US5324653A (en) * 1988-02-11 1994-06-28 Gist-Brocades N.V. Recombinant genetic means for the production of serine protease muteins
US5116741A (en) 1988-04-12 1992-05-26 Genex Corporation Biosynthetic uses of thermostable proteases
US5246849A (en) 1988-04-12 1993-09-21 Enzon, Inc. Thermally stable serine proteases
US5118623A (en) * 1988-05-27 1992-06-02 Solvay Enzymes, Inc. Bleach stable enzymes
AU618675B2 (en) 1989-05-17 1992-01-02 Amgen, Inc. Multiply mutated subtilisins
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
EP0405902A1 (fr) 1989-06-26 1991-01-02 Unilever Plc Compositions détergentes enzymatiques
DK316989D0 (da) 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
BR9006827A (pt) 1989-06-26 1991-08-06 Unilever Nv Composicoes detergentes enzimaticas
US5352603A (en) * 1989-08-31 1994-10-04 Kali-Chemie Ag Highly alkaline proteases
US6271012B1 (en) * 1989-10-11 2001-08-07 Genencor International, Inc. Protease muteins and their use in detergents
DE4009534A1 (de) * 1990-03-24 1991-09-26 Henkel Kgaa Fluessiges handreinigungsmittel
DK97190D0 (da) * 1990-04-19 1990-04-19 Novo Nordisk As Oxidationsstabile detergentenzymer
US5629173A (en) * 1990-08-09 1997-05-13 Genentech, Inc. Methods of use of serine protease variants having peptide ligase activity
DE69131834T2 (de) * 1990-08-09 2000-05-31 Genentech, Inc. Serinproteasevarianten mit peptidligase aktivität
DK271490D0 (da) * 1990-11-14 1990-11-14 Novo Nordisk As Detergentkomposition
EP0563169B2 (fr) 1990-12-21 2006-04-12 Novozymes A/S MUTANTS ENZYMATIQUES PRESENTANT UN FAIBLE DEGRE DE VARIATION DE LA CHARGE MOLECULAIRE DANS UNE PLAGE DE pH
US5482849A (en) * 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
DE4224125A1 (de) * 1991-07-27 1993-01-28 Solvay Enzymes Gmbh & Co Kg Verfahren zur verbesserung der stabilitaet von enzymen und stabilisierte enzyme
US5275945A (en) * 1991-10-08 1994-01-04 Vista Chemical Company Alkaline proteases stable in heavy-duty detergent liquids
ES2296285T3 (es) 1992-07-17 2008-04-16 Genencor International, Inc. Serin proteasas altamente alcalinas.
US5470733A (en) * 1993-06-01 1995-11-28 University Of Maryland Calcium free subtilisin mutants
US5567601A (en) * 1993-06-01 1996-10-22 University Of Maryland Subtilisin mutants lacking a primary calcium binding site
AU7870394A (en) 1993-09-15 1995-04-03 Procter & Gamble Company, The Subtilisin bpn' variants with decreased adsorption and increased hydrolysis
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
BR9407833A (pt) * 1993-10-14 1997-05-13 Procter & Gamble Composições alvejantes compreendendo enzimas protease
BR9407834A (pt) * 1993-10-14 1997-05-13 Procter & Gamble Composições de limpeza contendo protease
ES2364774T3 (es) * 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US5780285A (en) * 1995-03-03 1998-07-14 Genentech, Inc. Subtilisin variants capable of cleaving substrates containing dibasic residues

Also Published As

Publication number Publication date
CA2214348C (fr) 2001-10-30
MX9706851A (es) 1997-11-29
CA2214348A1 (fr) 1996-09-19
HUP9800765A2 (hu) 1998-07-28
ZA961631B (en) 1996-09-06
WO1996028566A2 (fr) 1996-09-19
JPH11501812A (ja) 1999-02-16
CZ279397A3 (en) 1997-11-12
IL117266A0 (en) 1996-06-18
HUP9800765A3 (en) 2001-01-29
US6455295B1 (en) 2002-09-24
CN1183119A (zh) 1998-05-27
BR9607356A (pt) 1999-06-15
AU4868896A (en) 1996-10-02
WO1996028566A3 (fr) 1997-07-10
EP0813596A2 (fr) 1997-12-29

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