LV13564B - Methods and compositions for treating ophtalmic conditions with retinyl derivatives - Google Patents
Methods and compositions for treating ophtalmic conditions with retinyl derivatives Download PDFInfo
- Publication number
- LV13564B LV13564B LVP-07-05A LV070005A LV13564B LV 13564 B LV13564 B LV 13564B LV 070005 A LV070005 A LV 070005A LV 13564 B LV13564 B LV 13564B
- Authority
- LV
- Latvia
- Prior art keywords
- group
- compound
- alkyl
- hpr
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
- G01N2800/164—Retinal disorders, e.g. retinopathy
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58229304P | 2004-06-23 | 2004-06-23 | |
US62969504P | 2004-11-19 | 2004-11-19 | |
US66090405P | 2005-03-11 | 2005-03-11 | |
US67240505P | 2005-04-18 | 2005-04-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
LV13564B true LV13564B (en) | 2008-02-20 |
Family
ID=34981643
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LVP-07-05A LV13564B (en) | 2004-06-23 | 2007-01-19 | Methods and compositions for treating ophtalmic conditions with retinyl derivatives |
Country Status (27)
Country | Link |
---|---|
US (3) | US8314152B2 (fr) |
EP (3) | EP2025336A1 (fr) |
JP (1) | JP4855396B2 (fr) |
KR (1) | KR100862930B1 (fr) |
AR (1) | AR049929A1 (fr) |
AT (1) | ATE404188T1 (fr) |
AU (1) | AU2005262558B8 (fr) |
BR (1) | BRPI0512569A (fr) |
CA (1) | CA2569691C (fr) |
CY (1) | CY1110435T1 (fr) |
DE (1) | DE602005008970D1 (fr) |
DK (1) | DK1768657T3 (fr) |
EA (1) | EA011864B1 (fr) |
ES (1) | ES2313368T3 (fr) |
GE (1) | GEP20084520B (fr) |
HK (1) | HK1107671A1 (fr) |
IL (1) | IL179872A (fr) |
LV (1) | LV13564B (fr) |
MX (1) | MXPA06014978A (fr) |
NO (1) | NO20070408L (fr) |
NZ (1) | NZ551955A (fr) |
PL (1) | PL1768657T3 (fr) |
PT (1) | PT1768657E (fr) |
SG (1) | SG140607A1 (fr) |
SI (1) | SI1768657T1 (fr) |
TW (1) | TWI396532B (fr) |
WO (1) | WO2006007314A1 (fr) |
Families Citing this family (44)
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EP2327400A3 (fr) | 2003-03-14 | 2011-10-19 | University of Washington | Substituts de retinoides et agonistes d'ospine et methodes d'utilisation correspondantes |
US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
EP1722766A2 (fr) | 2004-02-17 | 2006-11-22 | President And Fellows Of Harvard College | Gestion de troubles ophtalmologiques, notamment la degenerescence maculaire |
JP2007525496A (ja) * | 2004-02-17 | 2007-09-06 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 黄班変性症を含む眼科疾患の管理 |
SI1765322T1 (sl) | 2004-06-18 | 2014-03-31 | University Of Washington Intellectual Property And Technology Transfer 4311 | Derivati retinala in postopki za njihovo uporabo za zdravljenje motenj vida |
DK1768657T3 (da) | 2004-06-23 | 2008-12-01 | Sirion Therapeutics Inc | Fremgangsmåder og sammensætninger til at behandle ophthalmiske tilstande med retinylderivater |
US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
JP2008515778A (ja) * | 2004-08-18 | 2008-05-15 | シリオン セラピューティクス, インコーポレイテッド | 眼の状態を13−シス−レチニル誘導体で処置するための組み合わせ方法、組成物および治療 |
CA2580363A1 (fr) * | 2004-10-28 | 2006-05-11 | Idexx Laboratories, Inc. | Compositions destinees a l'administration controlee de composes pharmaceutiquement actifs |
AU2005304822B2 (en) * | 2004-11-04 | 2008-10-16 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation |
SG144145A1 (en) * | 2004-12-08 | 2008-07-29 | Sirion Therapeutics Inc | Methods, assays and compositions for treating retinol-related diseases |
UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
US8114440B2 (en) * | 2005-11-16 | 2012-02-14 | Idexx Laboratories Inc. | Pharmaceutical compositions for the administration of aptamers |
US7754679B2 (en) * | 2005-11-16 | 2010-07-13 | Idexx Laboratories, Inc. | Pharmaceutical compositions for the administration of aptamers |
EP2037951A2 (fr) * | 2006-06-22 | 2009-03-25 | Sirion Therapeutics, Inc. | Procédés et compositions pour traiter des conditions ophtalmiques par la modulation de l'activité de mégaline |
AU2007277032A1 (en) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Opsin stabilizing compounds and methods of use |
WO2008013984A2 (fr) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions et méthodes destinées à traiter et/ou à prévenir des maladies ophtalmologiques |
CA2657164A1 (fr) * | 2006-07-27 | 2008-01-31 | University Of Florida Research Foundation, Inc. | Compositions et methodes destinees a traiter ou a prevenir la phototoxicite oculaire |
US8828960B2 (en) * | 2007-07-17 | 2014-09-09 | Idexx Laboratories, Inc. | Amino acid vitamin ester compositions for controlled delivery of pharmaceutically active compounds |
WO2009102418A1 (fr) | 2008-02-11 | 2009-08-20 | University Of Washington | Procédés pour le traitement et la prévention d'un dysfonctionnement rétinien lié à l'âge |
WO2009114136A2 (fr) * | 2008-03-12 | 2009-09-17 | Albert Einstein College Of Medicine Of Yeshiva University | Dérivés de fenrétinide et leurs utilisations comme agents thérapeutiques, de diagnostic et d'imagerie |
US20100016218A1 (en) * | 2008-07-14 | 2010-01-21 | Otonomy, Inc. | Controlled-release apoptosis modulating compositions and methods for the treatment of otic disorders |
ES2549916T3 (es) * | 2009-05-04 | 2015-11-03 | Acucela, Inc. | Composiciones para usar en el tratamiento de glaucoma o hipertensión ocular |
IN2012DN00352A (fr) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
AU2009352678B2 (en) | 2009-09-15 | 2015-05-21 | Eluminex Biosciences (Suzhou) Limited | Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle |
JP5815552B2 (ja) | 2009-12-08 | 2015-11-17 | ケース ウェスタン リザーブ ユニバーシティCase Westernreserve University | 眼疾患を治療する化合物および方法 |
EP2563350B1 (fr) * | 2010-04-19 | 2020-10-14 | Retinagenix Therapeutics, Inc. | Régime et procédé thérapeutique pour le traitement ou l'amélioration de troubles de la vue associés à une carence en rétinoïdes endogènes |
EP2785346A4 (fr) | 2011-11-30 | 2015-04-29 | Bikam Pharmaceuticals Inc | Ligands de liaison aux opsines, compositions et procédés d'utilisation |
CN104125830B (zh) * | 2012-02-10 | 2018-01-16 | 台湾微脂体股份有限公司 | 用以减少眼用类固醇的并发症的药物组合物 |
BR112014021602A2 (pt) | 2012-03-01 | 2021-06-08 | Quadra Logic Tech Inc | uso, kit e derivado de retinal sintético para melhorar a função visual em distúrbios visuais associados com a deficiência de produção endógena de retinóide |
US9011845B2 (en) | 2012-06-26 | 2015-04-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Methods for treatment of inflammatory and infectious viral diseases |
US8877183B2 (en) | 2012-06-26 | 2014-11-04 | National Institutes Of Health (Nih) | Methods for treatment of ocular diseases |
US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
US10092393B2 (en) | 2013-03-14 | 2018-10-09 | Allotex, Inc. | Corneal implant systems and methods |
WO2015184453A1 (fr) * | 2014-05-30 | 2015-12-03 | Case Western Reserve University | Dérivés de rétinylamine pour le traitement de troubles oculaires |
MX2017004629A (es) | 2014-10-24 | 2017-06-30 | Takeda Pharmaceuticals Co | Compuesto heterociclico. |
CN107249678B (zh) * | 2014-12-19 | 2021-02-19 | 凯敏工业公司 | 使用离子电渗法进行生物活性分子的眼内递送 |
US10449090B2 (en) | 2015-07-31 | 2019-10-22 | Allotex, Inc. | Corneal implant systems and methods |
WO2017142854A1 (fr) * | 2016-02-15 | 2017-08-24 | Kemin Industries, Inc. | Liposomes positivement chargés en tant que supports de molécules lipophiles |
US11395853B2 (en) * | 2016-06-23 | 2022-07-26 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions |
US11369695B2 (en) | 2016-12-05 | 2022-06-28 | The Jackson Laboratory | Fat droplets in retina and optic nerve as a diagnostic marker for neurodegeneration and glaucoma in humans |
US11931327B2 (en) | 2017-07-04 | 2024-03-19 | Daiichi Sankyo Company, Limited | Drug for retinal degenerative disease associated with photoreceptor degeneration |
CA3137034A1 (fr) * | 2019-05-06 | 2020-11-12 | Howard J. Federoff | Compositions et methodes pour traiter la degenerescence maculaire liee a l'age |
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US7566808B2 (en) * | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
EP1722766A2 (fr) * | 2004-02-17 | 2006-11-22 | President And Fellows Of Harvard College | Gestion de troubles ophtalmologiques, notamment la degenerescence maculaire |
EP1727529B1 (fr) | 2004-03-17 | 2016-03-02 | Lars Michael Larsen | Prevention de la retinopathie par inhibition du cycle visuel |
SI1765322T1 (sl) | 2004-06-18 | 2014-03-31 | University Of Washington Intellectual Property And Technology Transfer 4311 | Derivati retinala in postopki za njihovo uporabo za zdravljenje motenj vida |
DK1768657T3 (da) | 2004-06-23 | 2008-12-01 | Sirion Therapeutics Inc | Fremgangsmåder og sammensætninger til at behandle ophthalmiske tilstande med retinylderivater |
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AU2005304822B2 (en) * | 2004-11-04 | 2008-10-16 | Sirion Therapeutics, Inc. | Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation |
SG144145A1 (en) | 2004-12-08 | 2008-07-29 | Sirion Therapeutics Inc | Methods, assays and compositions for treating retinol-related diseases |
UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding |
-
2005
- 2005-06-06 DK DK05758777T patent/DK1768657T3/da active
- 2005-06-06 ES ES05758777T patent/ES2313368T3/es active Active
- 2005-06-06 MX MXPA06014978A patent/MXPA06014978A/es active IP Right Grant
- 2005-06-06 PT PT05758777T patent/PT1768657E/pt unknown
- 2005-06-06 EP EP08014275A patent/EP2025336A1/fr not_active Withdrawn
- 2005-06-06 KR KR1020077001270A patent/KR100862930B1/ko not_active IP Right Cessation
- 2005-06-06 BR BRPI0512569-3A patent/BRPI0512569A/pt not_active IP Right Cessation
- 2005-06-06 DE DE602005008970T patent/DE602005008970D1/de active Active
- 2005-06-06 CA CA2569691A patent/CA2569691C/fr not_active Expired - Fee Related
- 2005-06-06 AU AU2005262558A patent/AU2005262558B8/en not_active Ceased
- 2005-06-06 AT AT05758777T patent/ATE404188T1/de active
- 2005-06-06 EP EP10181656A patent/EP2277516A1/fr not_active Withdrawn
- 2005-06-06 SI SI200530415T patent/SI1768657T1/sl unknown
- 2005-06-06 WO PCT/US2005/020080 patent/WO2006007314A1/fr active Application Filing
- 2005-06-06 EP EP05758777A patent/EP1768657B1/fr not_active Not-in-force
- 2005-06-06 GE GEAP20059816A patent/GEP20084520B/en unknown
- 2005-06-06 JP JP2007518098A patent/JP4855396B2/ja not_active Expired - Fee Related
- 2005-06-06 NZ NZ551955A patent/NZ551955A/en not_active IP Right Cessation
- 2005-06-06 EA EA200700109A patent/EA011864B1/ru not_active IP Right Cessation
- 2005-06-06 SG SG200801546-3A patent/SG140607A1/en unknown
- 2005-06-06 PL PL05758777T patent/PL1768657T3/pl unknown
- 2005-06-10 US US11/150,641 patent/US8314152B2/en not_active Expired - Fee Related
- 2005-06-21 AR ARP050102545A patent/AR049929A1/es not_active Application Discontinuation
- 2005-06-22 TW TW094120880A patent/TWI396532B/zh not_active IP Right Cessation
-
2006
- 2006-12-06 IL IL179872A patent/IL179872A/en not_active IP Right Cessation
-
2007
- 2007-01-19 LV LVP-07-05A patent/LV13564B/lv unknown
- 2007-01-22 NO NO20070408A patent/NO20070408L/no not_active Application Discontinuation
- 2007-12-06 HK HK07113340.3A patent/HK1107671A1/xx not_active IP Right Cessation
-
2008
- 2008-11-12 CY CY20081101287T patent/CY1110435T1/el unknown
-
2010
- 2010-04-21 US US12/764,764 patent/US8410168B2/en not_active Expired - Fee Related
-
2011
- 2011-05-27 US US13/118,330 patent/US20110294891A1/en not_active Abandoned
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