LV13498B - Immunostimulant composition comprising at least one toll-like receptor 7 or toll-like receptor 8 agonist and a toll-like receptor 4 agonist - Google Patents
Immunostimulant composition comprising at least one toll-like receptor 7 or toll-like receptor 8 agonist and a toll-like receptor 4 agonist Download PDFInfo
- Publication number
- LV13498B LV13498B LVP-06-87A LV060087A LV13498B LV 13498 B LV13498 B LV 13498B LV 060087 A LV060087 A LV 060087A LV 13498 B LV13498 B LV 13498B
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- toll
- receptor
- agonist
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Chemical Kinetics & Catalysis (AREA)
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- Mycology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
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- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (8)
1. Imūnstimulējoša kompozīcija, kas ietver vismaz vienu Toll-veida receptora 7 vai Toll-veida receptora 8 agonistu, kas raksturīga ar to, ka tā papildus ietver Toll-veida receptora 4 agonistu.
2. Imūnstimulējoša kompozīcija saskaņā ar iepriekšējo pretenziju, kas raksturīga ar to, ka Toll-veida receptora 7 vai Toll-veida receptora 8 agonists ir atšķirīgs no Toll-veida receptora 4 agonista.
3. Imūnstimulējošā kompozīcija saskaņā ar 1. vai 2.pretenziju, kas raksturīga arto, ka tā papildus ietver vismaz vienu vakcīnas antigēnu.
4. Imūnstimulējošā kompozīcija saskaņā ar jebkuru no iepriekšējām pretenzijām, kas raksturīga ar to, ka Toll-veida receptora 7 agonists ir imidazohonolinamīna atvasinājums.
5. Imūnstimulējošā kompozīcija saskaņā ar jebkuru no iepriekšējām pretenzijām, kas raksturīga ar to, ka imidazohonolinamīna atvasinājums ir 4-amino-2-etoksimetil-a,a-dimetil-1H-imidazo[4,5-cjhinolin-1-etanols.
6. imūnstimulējošā kompozīcija saskaņā ar jebkuru no iepriekšējām pretenzijām, kas raksturīga ar to, ka Toll-veida receptora 4 agonists ir ER804057.
7. Imūnstimulējošās kompozīcijas saskaņā ar jebkuru no iepriekšējām pretenzijām izmantošana medikamenta ražošanai.
8. Imūnstimulējošās kompozīcijas saskaņā ar jebkuru pretenziju no 1. līdz 6.izmantošana tāda medikamenta ražošanai, kas ir spējīgs izraisīt TH1 tipa imūnatbildi.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0314995A FR2863890B1 (fr) | 2003-12-19 | 2003-12-19 | Composition immunostimulante |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LV13498B true LV13498B (en) | 2007-05-20 |
Family
ID=34630344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-06-87A LV13498B (en) | 2003-12-19 | 2006-06-19 | Immunostimulant composition comprising at least one toll-like receptor 7 or toll-like receptor 8 agonist and a toll-like receptor 4 agonist |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20070087009A1 (lv) |
| EP (1) | EP1750707B1 (lv) |
| JP (1) | JP2007514725A (lv) |
| KR (1) | KR20060124669A (lv) |
| CN (1) | CN1921862A (lv) |
| AU (1) | AU2004305276B2 (lv) |
| BR (1) | BRPI0417192A (lv) |
| CA (1) | CA2549114C (lv) |
| FR (1) | FR2863890B1 (lv) |
| IL (1) | IL176270A0 (lv) |
| LV (1) | LV13498B (lv) |
| NO (1) | NO20063254L (lv) |
| WO (1) | WO2005060966A1 (lv) |
| ZA (1) | ZA200605250B (lv) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2006207891C1 (en) | 2005-01-28 | 2011-09-01 | Galen Bio, Inc. | Immunologically active compositions |
| WO2006116423A2 (en) * | 2005-04-26 | 2006-11-02 | Eisai Co., Ltd | Compositions and methods for cancer immunotherapy |
| ES2577514T3 (es) * | 2005-08-22 | 2016-07-15 | The Regents Of The University Of California | Antagonistas de TLR |
| CA2636424A1 (en) * | 2006-01-09 | 2007-10-25 | The Regents Of The University Of California | Immunostimulatory combinations of tnfrsf, tlr, nlr, rhr, purinergic receptor, and cytokine receptor agonists for vaccines and tumor immunotherapy |
| CA2653941C (en) | 2006-05-31 | 2013-01-08 | The Regents Of The University Of California | Substituted amino purine derivatives and uses thereof |
| AU2008302276B2 (en) | 2006-09-29 | 2013-10-10 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| KR101515489B1 (ko) | 2006-09-29 | 2015-04-30 | 다케다 백신즈 인코포레이티드 | 노로바이러스 백신 제제 |
| SI2510946T1 (sl) * | 2007-02-07 | 2015-12-31 | The Regents Of The University Of California | Konjugati sintetičnih agonistov TLR in njihove uporabe |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| EA201001264A1 (ru) * | 2008-02-07 | 2011-04-29 | Дзе Регентс Оф Дзе Юниверсити Оф Калифорния | Способ лечения заболеваний мочевого пузыря с помощью активатора tlr7 |
| US20110104293A1 (en) * | 2008-07-01 | 2011-05-05 | Bali Pulendran | Synergistic induction of humoral and cellular immunity by combinatorial activation of toll-like receptors |
| SG2013057732A (en) | 2008-08-08 | 2015-02-27 | Ligocyte Pharmaceuticals Inc | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
| WO2010088924A1 (en) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
| MX2011008500A (es) | 2009-02-11 | 2011-09-26 | Univ California | Moduladores del receptor tipo toll y tratamiento de enfermedades. |
| EP2575773A4 (en) * | 2010-05-26 | 2014-06-25 | Selecta Biosciences Inc | SYNTHETIC NANOTRÄGERKOMBINATIONSIMPFSTOFFE |
| EA029470B1 (ru) | 2011-07-11 | 2018-03-30 | Такеда Вэксинс, Инк. | Способ стимулирования формирования защитного иммунитета против норовируса |
| CA3116265A1 (en) | 2014-10-07 | 2016-04-14 | Cytlimic Inc. | Hsp70-derived peptide, pharmaceutical composition for treating or preventing cancer using same, immunity inducer, and method for producing antigen-presenting cell |
| RU2714117C2 (ru) | 2015-03-09 | 2020-02-11 | Ситлимик Инк. | Пептид, полученный из gpc3, фармацевтическая композиция для лечения или предотвращения рака с его использованием, индуктор иммунитета и способ получения антиген-презентирующих клеток |
| EP3797794A1 (en) | 2015-04-07 | 2021-03-31 | Cytlimic Inc. | Medicine comprising a toll like receptor 3 agonist and a lag-3 protein |
| US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
| WO2018070069A1 (ja) | 2016-10-11 | 2018-04-19 | サイトリミック株式会社 | 医薬 |
| US10508115B2 (en) * | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5389640A (en) * | 1991-03-01 | 1995-02-14 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
| KR100711561B1 (ko) * | 1999-02-01 | 2007-04-27 | 에-자이가부시기가이샤 | 면역학적 보조제 화합물 |
| EP1478371A4 (en) * | 2001-10-12 | 2007-11-07 | Univ Iowa Res Found | METHODS AND PRODUCTS FOR ENHANCING IMMUNE RESPONSES USING IMIDAZOQUINOLINE COMPOUND |
| JP2005513021A (ja) * | 2001-11-16 | 2005-05-12 | スリーエム イノベイティブ プロパティズ カンパニー | Ｉｒｍ化合物およびトール様受容体経路に関する方法および組成物 |
| NZ573064A (en) * | 2002-04-04 | 2011-02-25 | Coley Pharm Gmbh | Immunostimulatory G,U-containing oligoribonucleotides |
| US20040248837A1 (en) * | 2002-11-01 | 2004-12-09 | Eyal Raz | Methods of treating pulmonary fibrotic disorders |
| JP2006512391A (ja) * | 2002-12-30 | 2006-04-13 | スリーエム イノベイティブ プロパティズ カンパニー | 組み合わせ免疫賦活薬 |
| WO2005016235A2 (en) * | 2003-04-14 | 2005-02-24 | The Regents Of The University Of California | Combined use of impdh inhibitors with toll-like receptor agonists |
| GB0321615D0 (en) * | 2003-09-15 | 2003-10-15 | Glaxo Group Ltd | Improvements in vaccination |
| KR20070052273A (ko) * | 2004-06-30 | 2007-05-21 | 아이디 바이오메디컬 코포레이션 오브 퀘벡 | 코로나바이러스 감염의 치료를 위한 백신 조성물 |
-
2003
- 2003-12-19 FR FR0314995A patent/FR2863890B1/fr not_active Expired - Fee Related
-
2004
- 2004-12-20 WO PCT/FR2004/003308 patent/WO2005060966A1/fr active Application Filing
- 2004-12-20 KR KR1020067013424A patent/KR20060124669A/ko not_active Application Discontinuation
- 2004-12-20 US US10/596,432 patent/US20070087009A1/en not_active Abandoned
- 2004-12-20 ZA ZA200605250A patent/ZA200605250B/en unknown
- 2004-12-20 JP JP2006544506A patent/JP2007514725A/ja active Pending
- 2004-12-20 CA CA2549114A patent/CA2549114C/en not_active Expired - Fee Related
- 2004-12-20 AU AU2004305276A patent/AU2004305276B2/en not_active Ceased
- 2004-12-20 EP EP04816441.2A patent/EP1750707B1/fr active Active
- 2004-12-20 CN CNA2004800419471A patent/CN1921862A/zh active Pending
- 2004-12-20 BR BRPI0417192-6A patent/BRPI0417192A/pt not_active IP Right Cessation
-
2006
- 2006-06-12 IL IL176270A patent/IL176270A0/en active IP Right Grant
- 2006-06-19 LV LVP-06-87A patent/LV13498B/en unknown
- 2006-07-13 NO NO20063254A patent/NO20063254L/no not_active Application Discontinuation
-
2010
- 2010-06-09 US US12/797,107 patent/US20100247557A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2549114A1 (en) | 2005-07-07 |
| JP2007514725A (ja) | 2007-06-07 |
| BRPI0417192A (pt) | 2007-03-06 |
| US20100247557A1 (en) | 2010-09-30 |
| KR20060124669A (ko) | 2006-12-05 |
| AU2004305276B2 (en) | 2010-07-01 |
| WO2005060966A1 (fr) | 2005-07-07 |
| ZA200605250B (en) | 2007-11-28 |
| EP1750707B1 (fr) | 2018-03-14 |
| AU2004305276A1 (en) | 2005-07-07 |
| CA2549114C (en) | 2013-05-14 |
| FR2863890B1 (fr) | 2006-03-24 |
| EP1750707A1 (fr) | 2007-02-14 |
| NO20063254L (no) | 2006-07-13 |
| IL176270A0 (en) | 2006-10-05 |
| US20070087009A1 (en) | 2007-04-19 |
| FR2863890A1 (fr) | 2005-06-24 |
| CN1921862A (zh) | 2007-02-28 |
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