LV12722B - PRV-1 GAME AND ITS USE - Google Patents
PRV-1 GAME AND ITS USE Download PDFInfo
- Publication number
- LV12722B LV12722B LVP-01-61A LV010061A LV12722B LV 12722 B LV12722 B LV 12722B LV 010061 A LV010061 A LV 010061A LV 12722 B LV12722 B LV 12722B
- Authority
- LV
- Latvia
- Prior art keywords
- polypeptide
- sequence
- prv
- amino acid
- polynucleotide
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract description 42
- 101000980845 Homo sapiens CD177 antigen Proteins 0.000 claims abstract description 73
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 68
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 68
- 229920001184 polypeptide Polymers 0.000 claims abstract description 66
- 239000002773 nucleotide Substances 0.000 claims abstract description 40
- 125000003729 nucleotide group Chemical group 0.000 claims abstract description 40
- 238000000034 method Methods 0.000 claims abstract description 25
- 102100024209 CD177 antigen Human genes 0.000 claims description 61
- 150000001413 amino acids Chemical class 0.000 claims description 31
- 108091033319 polynucleotide Proteins 0.000 claims description 31
- 102000040430 polynucleotide Human genes 0.000 claims description 31
- 239000002157 polynucleotide Substances 0.000 claims description 31
- 239000012634 fragment Substances 0.000 claims description 25
- 208000008601 Polycythemia Diseases 0.000 claims description 13
- 108020004511 Recombinant DNA Proteins 0.000 claims description 12
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- 238000002360 preparation method Methods 0.000 claims description 10
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 7
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- 238000003757 reverse transcription PCR Methods 0.000 claims description 5
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- 102000053602 DNA Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
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- 235000015110 jellies Nutrition 0.000 description 2
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- 102000039446 nucleic acids Human genes 0.000 description 2
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- 238000001890 transfection Methods 0.000 description 2
- 238000001262 western blot Methods 0.000 description 2
- 101150072531 10 gene Proteins 0.000 description 1
- 208000031261 Acute myeloid leukaemia Diseases 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 201000005569 Gout Diseases 0.000 description 1
- 206010018690 Granulocytosis Diseases 0.000 description 1
- 108010043121 Green Fluorescent Proteins Proteins 0.000 description 1
- 102000004144 Green Fluorescent Proteins Human genes 0.000 description 1
- 208000023661 Haematological disease Diseases 0.000 description 1
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- 241000238631 Hexapoda Species 0.000 description 1
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- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 241001529936 Murinae Species 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 102000000447 Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase Human genes 0.000 description 1
- 108010055817 Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase Proteins 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 108020004682 Single-Stranded DNA Proteins 0.000 description 1
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- 206010041660 Splenomegaly Diseases 0.000 description 1
- 208000005485 Thrombocytosis Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 238000001261 affinity purification Methods 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 125000000613 asparagine group Chemical group N[C@@H](CC(N)=O)C(=O)* 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000010367 cloning Methods 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 231100000433 cytotoxic Toxicity 0.000 description 1
- 230000001472 cytotoxic effect Effects 0.000 description 1
- 230000022811 deglycosylation Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 238000001502 gel electrophoresis Methods 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 230000013595 glycosylation Effects 0.000 description 1
- 238000006206 glycosylation reaction Methods 0.000 description 1
- 229930004094 glycosylphosphatidylinositol Natural products 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 210000004408 hybridoma Anatomy 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000007912 intraperitoneal administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
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- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 230000002297 mitogenic effect Effects 0.000 description 1
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- 230000035772 mutation Effects 0.000 description 1
- 208000004235 neutropenia Diseases 0.000 description 1
- 230000003448 neutrophilic effect Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
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- 238000003127 radioimmunoassay Methods 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000001177 retroviral effect Effects 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
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- 210000002966 serum Anatomy 0.000 description 1
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- 230000004083 survival effect Effects 0.000 description 1
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- 206010043554 thrombocytopenia Diseases 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 102000009816 urokinase plasminogen activator receptor activity proteins Human genes 0.000 description 1
- 108040001269 urokinase plasminogen activator receptor activity proteins Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19849044A DE19849044A1 (de) | 1998-10-23 | 1998-10-23 | Das Gen PRV-1 und dessen Verwendung |
PCT/EP1999/007238 WO2000024886A1 (de) | 1998-10-23 | 1999-09-30 | Das gen prv-1 und dessen verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
LV12722A LV12722A (lv) | 2001-09-20 |
LV12722B true LV12722B (en) | 2002-01-20 |
Family
ID=7885492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LVP-01-61A LV12722B (en) | 1998-10-23 | 2001-05-22 | PRV-1 GAME AND ITS USE |
Country Status (28)
Country | Link |
---|---|
US (2) | US6686153B1 (bg) |
EP (1) | EP1123392B1 (bg) |
JP (1) | JP2002528077A (bg) |
KR (1) | KR20010080883A (bg) |
CN (1) | CN1190491C (bg) |
AT (1) | ATE348109T1 (bg) |
AU (1) | AU771772B2 (bg) |
BG (1) | BG105460A (bg) |
BR (1) | BR9915537A (bg) |
CA (1) | CA2349211A1 (bg) |
CZ (1) | CZ20011430A3 (bg) |
DE (2) | DE19849044A1 (bg) |
EA (1) | EA200100440A1 (bg) |
EE (1) | EE200100234A (bg) |
HR (1) | HRP20010294A2 (bg) |
HU (1) | HUP0104954A3 (bg) |
IL (1) | IL142664A0 (bg) |
LT (1) | LT4877B (bg) |
LV (1) | LV12722B (bg) |
MX (1) | MXPA01004035A (bg) |
NO (1) | NO20011961L (bg) |
NZ (1) | NZ510970A (bg) |
PL (1) | PL347413A1 (bg) |
SI (1) | SI20585A (bg) |
SK (1) | SK5402001A3 (bg) |
WO (1) | WO2000024886A1 (bg) |
YU (1) | YU29801A (bg) |
ZA (1) | ZA200103210B (bg) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1141285A2 (en) * | 1998-12-16 | 2001-10-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
DE19947010A1 (de) * | 1999-09-30 | 2001-04-05 | Universitaetsklinikum Freiburg | Das Gen PRV-1 und dessen Verwendung |
CA2715080C (en) | 2007-09-28 | 2021-09-28 | Intrexon Corporation | Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU746956B2 (en) * | 1997-05-06 | 2002-05-09 | Zymogenetics Inc. | Novel tumor antigens |
-
1998
- 1998-10-23 DE DE19849044A patent/DE19849044A1/de not_active Withdrawn
-
1999
- 1999-09-30 NZ NZ510970A patent/NZ510970A/xx unknown
- 1999-09-30 DE DE59914061T patent/DE59914061D1/de not_active Expired - Lifetime
- 1999-09-30 HU HU0104954A patent/HUP0104954A3/hu unknown
- 1999-09-30 WO PCT/EP1999/007238 patent/WO2000024886A1/de active IP Right Grant
- 1999-09-30 MX MXPA01004035A patent/MXPA01004035A/es unknown
- 1999-09-30 SK SK540-2001A patent/SK5402001A3/sk unknown
- 1999-09-30 CZ CZ20011430A patent/CZ20011430A3/cs unknown
- 1999-09-30 PL PL99347413A patent/PL347413A1/xx not_active Application Discontinuation
- 1999-09-30 AT AT99947439T patent/ATE348109T1/de not_active IP Right Cessation
- 1999-09-30 KR KR1020017005025A patent/KR20010080883A/ko not_active Application Discontinuation
- 1999-09-30 BR BR9915537-0A patent/BR9915537A/pt not_active IP Right Cessation
- 1999-09-30 EP EP99947439A patent/EP1123392B1/de not_active Expired - Lifetime
- 1999-09-30 IL IL14266499A patent/IL142664A0/xx unknown
- 1999-09-30 CN CNB998124834A patent/CN1190491C/zh not_active Expired - Fee Related
- 1999-09-30 AU AU60883/99A patent/AU771772B2/en not_active Ceased
- 1999-09-30 YU YU29801A patent/YU29801A/sh unknown
- 1999-09-30 CA CA002349211A patent/CA2349211A1/en not_active Abandoned
- 1999-09-30 EA EA200100440A patent/EA200100440A1/ru unknown
- 1999-09-30 JP JP2000578440A patent/JP2002528077A/ja active Pending
- 1999-09-30 SI SI9920078A patent/SI20585A/sl not_active IP Right Cessation
- 1999-09-30 US US09/830,189 patent/US6686153B1/en not_active Expired - Fee Related
- 1999-09-30 EE EEP200100234A patent/EE200100234A/xx unknown
-
2001
- 2001-04-19 ZA ZA200103210A patent/ZA200103210B/xx unknown
- 2001-04-20 NO NO20011961A patent/NO20011961L/no not_active Application Discontinuation
- 2001-04-20 BG BG105460A patent/BG105460A/bg unknown
- 2001-04-23 HR HR20010294A patent/HRP20010294A2/hr not_active Application Discontinuation
- 2001-05-22 LV LVP-01-61A patent/LV12722B/en unknown
- 2001-05-22 LT LT2001055A patent/LT4877B/lt not_active IP Right Cessation
-
2003
- 2003-12-05 US US10/727,619 patent/US20040259110A1/en not_active Abandoned
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