LV10308A - Ciliarais neirotropais faktors - Google Patents

Ciliarais neirotropais faktors

Info

Publication number
LV10308A
LV10308A LV930441A LV930441A LV10308A LV 10308 A LV10308 A LV 10308A LV 930441 A LV930441 A LV 930441A LV 930441 A LV930441 A LV 930441A LV 10308 A LV10308 A LV 10308A
Authority
LV
Latvia
Prior art keywords
cntf
nucleic acid
acid sequences
relates
variety
Prior art date
Application number
LV930441A
Other languages
English (en)
Latvian (lv)
Inventor
Piotr Masiakowski
Vivien Wong
Nikos Panayotatos
Hans Friedrich Erwin Thoenen
Kurt A Stockli-Rippstein
Michael Sendtner
Yoshihiro Arakawa
Patrick Desmond Carroll
Rudolf George Gotz
George W Kreutzberg
Dan B Lindholm
Friedrich Lottspeich
Nancy Ip
Mark E Furth
Original Assignee
Max Planck Gesellschaft
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27410749&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV10308(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Max Planck Gesellschaft, Regeneron Pharma filed Critical Max Planck Gesellschaft
Publication of LV10308A publication Critical patent/LV10308A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Psychology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
LV930441A 1989-09-15 1993-05-31 Ciliarais neirotropais faktors LV10308A (lv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40817289A 1989-09-15 1989-09-15
US42951789A 1989-10-31 1989-10-31
US57065190A 1990-08-20 1990-08-20
PCT/US1990/005241 WO1991004316A2 (fr) 1989-09-15 1990-09-14 Facteur neurotrophique ciliaire

Publications (1)

Publication Number Publication Date
LV10308A true LV10308A (lv) 1994-10-20

Family

ID=27410749

Family Applications (1)

Application Number Title Priority Date Filing Date
LV930441A LV10308A (lv) 1989-09-15 1993-05-31 Ciliarais neirotropais faktors

Country Status (11)

Country Link
US (1) US6602687B1 (fr)
EP (1) EP0448707B1 (fr)
JP (2) JPH05199879A (fr)
AT (1) ATE130365T1 (fr)
AU (1) AU705371B2 (fr)
CA (1) CA2040404A1 (fr)
DE (1) DE69023637T2 (fr)
ES (1) ES2084045T3 (fr)
IE (1) IE903130A1 (fr)
LV (1) LV10308A (fr)
WO (1) WO1991004316A2 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT405835B (de) * 1989-01-05 1999-11-25 Synergen Inc Aufgereinigter ziliärer neurotropher faktor
US5141856A (en) * 1989-01-05 1992-08-25 Synergen, Inc. Expression of purified ciliary neurotrophic factor
IL98304A (en) * 1990-06-01 2008-08-07 Regeneron Pharma The ciliary neurotrophic factor receptor
IT1247150B (it) * 1991-01-21 1994-12-12 Fidia Spa Processo per la sintesi e la purificazione del fattore neuronotroficociliare umano (cntf) da escherichia coli.
DK0593516T3 (da) * 1991-07-10 2001-09-17 Regeneron Pharma Fremgangsmåder til behandling af motorneuronsygdomme ved anvendelse af medlemmer af BDNF/NT-3/NGF-molekylfamilien
HUT67352A (en) * 1991-07-23 1995-03-28 Syntex Inc Recombinant ciliary neurotrophic factor and c-ferminal truncated ciliary neurotrophic factor, their production, and pharmaceutical products for treatment of peripheral nerveinjury, containing them
US5593857A (en) * 1991-08-23 1997-01-14 Scios Inc. Production of homogeneous truncated CNTF
WO1993007270A1 (fr) * 1991-10-01 1993-04-15 Genentech, Inc. Production d'un facteur neurotrophique dote d'une activite de promotion de la croissance (gpa)
JPH07503128A (ja) * 1991-11-11 1995-04-06 フィディーア・ソシエタ・ペル・アチオニ ヒト毛様体ニューロン親和性因子の先端欠失型および突然変異タンパク質型の合成と精製
AU4995193A (en) * 1992-08-04 1994-03-03 Regeneron Pharmaceuticals, Inc. Method of enhancing differentiation and survival of neuronal precursor cells
CA2145535C (fr) * 1992-09-25 2007-07-17 Axel Kahn Vecteurs adenoviraux pour le transfert de genes etrangers dans des cellules du systeme nerveux central, notamment dans le cerveau
US6472178B1 (en) 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
CA2155540A1 (fr) * 1993-02-08 1994-08-18 Frank Collins Methodes pour traiter la sclerose laterale amyotrophique a l'aide de cntf
ZA941729B (en) * 1993-03-12 1994-10-13 Max Planck Gesellschaft Treatment of motor neuron diseases with fibroblast growth factor-5 (fgf-5).
FR2705361B1 (fr) * 1993-05-18 1995-08-04 Centre Nat Rech Scient Vecteurs viraux et utilisation en thérapie génique.
DK0632008T3 (da) 1993-06-01 1998-09-23 Ono Pharmaceutical Co Pentansyrederivater
US6143714A (en) * 1994-10-24 2000-11-07 Regeneron Pharmaceuticals, Inc. Methods of using hepatocyte growth factor to promote survival, growth and differentiation of motor neurons
ATE386811T1 (de) 1996-04-05 2008-03-15 Novartis Vaccines & Diagnostic Alphaviren-vektors mit eine reduzierte inhibierung der synthese von zellmakromolekülen
FR2753379B1 (fr) * 1996-09-13 1998-10-30 Rhone Poulenc Rorer Sa Methode de traitement de la sclerose laterale amyotrophique
IT1288388B1 (it) 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
US6313089B1 (en) * 1997-08-20 2001-11-06 Duke University Complexes of apolipoprotein E and ciliary neurotrophic factor (CNTF) and methods of use
EP0999270A1 (fr) * 1998-10-09 2000-05-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procédé pour la régulation de l'expression du gène SMN
EP1365785A2 (fr) * 2000-05-24 2003-12-03 Regeneron Pharmaceuticals, Inc. Utilisation du facteur neurotrophique ciliaire
ATE503845T1 (de) 2001-12-10 2011-04-15 Novartis Pharma Gmbh Verfahren zur behandlung von psychosen und schizophrenie auf der basis eines polymorphismus im cntf gen
JP2005073592A (ja) * 2003-09-01 2005-03-24 Yukiguni Maitake Co Ltd マイタケ由来のレクチンをコードする遺伝子
US8592374B2 (en) 2007-03-16 2013-11-26 Research Foundation For Mental Hygiene, Inc. Neurotrophic peptides
EP2009103A1 (fr) 2007-03-16 2008-12-31 Ebewe Pharma Ges.m.b.H. Nfg. KG Peptides neurotrophes
CN105960454B (zh) * 2013-12-11 2020-10-30 住友化学株式会社 用于制备睫状缘区样结构的方法
CN112672732A (zh) * 2018-06-19 2021-04-16 细胞疗法有限责任公司 包含神经营养剂、凋亡信号传导片段抑制剂（FAS）或FAS配体（FASL）抑制剂、肿瘤坏死因子-α（TNF-α）或TNF受体抑制剂、线粒体肽、寡核苷酸、趋化因子抑制剂或半胱氨酸-天冬氨酸蛋白酶的药物递送系统
CN112566622A (zh) * 2018-06-19 2021-03-26 细胞疗法有限责任公司 用于治疗青光眼或高眼压症的包含眼内压降低剂、cnp化合物、npr-b化合物、tie-2激动剂或神经营养剂的缓释药物递送系统
US20230094423A1 (en) * 2019-12-18 2023-03-30 Cella Therapeutics, Llc Drug delivery systems comprising a neurotrophic agent, an apoptosis signaling fragment inhibitor (fas) or fas ligand (fasl) inhibitor, a tumor necrosis factor-alpha (tnf-alpha) or tnf receptor inhibitor, a mitochondrial peptide, an oligonucleotide, a chemokine inhibitor, or a cysteine-aspartic protease inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923696A (en) 1987-05-04 1990-05-08 Baylor College Of Medicine Method to prepare a neurotrophic composition
US5141856A (en) * 1989-01-05 1992-08-25 Synergen, Inc. Expression of purified ciliary neurotrophic factor
US5011914A (en) 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
US4997929A (en) 1989-01-05 1991-03-05 Synergen, Inc. Purified ciliary neurotrophic factor
EP0463082A1 (fr) * 1989-03-15 1992-01-02 The Regents Of The University Of California Facteur neurotrope ciliaire purifie
CA2038208A1 (fr) * 1990-03-14 1991-09-15 Francesco Della Valle Procede pour l'isolement et l'expression du facteur neuronotrophique a partir de la zone ciliaire humaine a l'aide d'une technique de l'adn recombinant

Also Published As

Publication number Publication date
JP2001354697A (ja) 2001-12-25
JPH05199879A (ja) 1993-08-10
ATE130365T1 (de) 1995-12-15
WO1991004316A3 (fr) 1991-04-18
ES2084045T3 (es) 1996-05-01
AU705371B2 (en) 1999-05-20
EP0448707A1 (fr) 1991-10-02
CA2040404A1 (fr) 1991-03-16
EP0448707A4 (en) 1992-11-19
US6602687B1 (en) 2003-08-05
DE69023637D1 (de) 1995-12-21
DE69023637T2 (de) 1996-10-17
IE903130A1 (en) 1991-03-27
EP0448707B1 (fr) 1995-11-15
WO1991004316A2 (fr) 1991-04-04
AU6740290A (en) 1991-04-18

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