LU84416A1 - SOFT CLEANING COMPOSITION - Google Patents

Description

Gentle cleaning composition.

The present invention relates to new gentle cleaning compositions which can be used in particular for cleaning the hair and the skin.

Non-ionic surfactants are well known in the art and have been commonly used in preparations for cleaning the skin or hair.

The Applicant has discovered that by combining certain of the nonionic surfactants with very specific nonionic polymers, it was possible to obtain a mild cleaning composition, having improved safety and detergency properties compared to to compositions containing only the nonionic surfactant.

The Applicant has in fact discovered that by combining certain nonionic surfactants with certain nonionic polymers, a very mild composition is obtained, the red cell half-lysis points of which are relatively high compared to the so-called cleaning compositions. mild based on non-ionic surfactants.

The Applicant has also discovered that the detergency of the composition is significantly improved compared to the detergency properties of the nonionic surfactant used alone in a conventional composition.

In order to determine the detergency and the aggressiveness of the cleaning compositions, the applicant has developed the following two tests.

Measuring aggressiveness Aggressiveness is determined by hemolysis of red blood cells from a blood sample. To this end, the half-lysis points of the different compositions are examined. The half-lysis point is the concentration of the product diluted in physiological saline which causes the lysis of 501 red cells. i

The higher the half-lysis point, the less aggressive the cleaning composition.

2

Detergency determination

A determined quantity of sebum is deposited on wool samples in the form of a stain. After washing the samples under standard conditions with an automatic machine and drying, the amount of residual sebum is revealed by revelation using osmic acid. A spot is thus obtained which, depending on the amount of sebum remaining, has a color ranging from pale gray to black. The darker the stain, the greater the amount of sebum remaining and the lower the detergency of the composition studied.

The following method is used and all measurements are performed in duplicate. 70 mg of artificial sebum having the following composition are applied to a sample of virgin wool: k Squalene 97% 19-d

Cholesterol puriss. 5%

Technical triolein 45%

Pure oleic acid 31%.

Washing is then carried out with an automatic machine mainly consisting of a movable plate, a pressing roller and nozzles delivering the water for rinsing.

The plate, when in action, is driven by an alternating movement and a frequency of 20 passages per minute (+ or - 3 seconds).

After fixing the sample on the plate, 0.75 ml of the composition to be tested is placed on the fabric and 60 roll passes are made (3 minutes). Then rinse by dispersing 240 ml of water and moving the tray and roller for 3 minutes (60 passes).

The washing is then repeated with 0.5 ml of composition to be tested, 60 passages of roller and rinsing with 240 ml of water and 120 passages of the roller (6 minutes).

The residual sebum is revealed using osmic acid vapors. In a sealed box, osmic acid is released which is left in contact with the sample for 5 minutes, this period of time is sufficient for the reaction with the sebum to be complete. / J

3

The intensity of the color of the stain is measured by a visual method using as a control a solution of sodium lauryl sulphate at a sodium lauryl sulphate content of X%. The intensity of the stain of the composition to be tested is compared to the intensity closest to the solution. tion of sodium lauryl sulfate. Control solutions are used for this purpose at varying concentrations of sodium lauryl sulfate.

The detergent activity is expressed in equivalent of sodium lauryl sulfate.

An object of the invention therefore consists of a cleaning composition containing at least certain nonionic surfactants associated with certain nonionic polymers.

Another object of the invention consists of a cleaning process using the above composition.

Other objects will appear on reading the description and the examples which follow.

The mild cleaning composition in accordance with the invention is essentially characterized in that it contains, in a cosmetically acceptable medium, at least one nonionic surfactant (I) chosen from: (i) the glucoside alkyl ethers corresponding to the formula: ch2oh r ch2oh η A - 0 y-0 \ L_y - νλρ — R. «> OH OH OH - n in which R denotes an alkyl radical having 8 to 10 carbon atoms, n is equal to 0 , 1, 2, 3 or 4; (ii) oxyethylenated or oxypropylenated methyl glucosides; (iii) optionally oxyethylated methyl glucoside sesquistearate; (iv) oxyethylenated methyl glucoside dioleate; (v) sucrose esters or sucrose esters; / (vi) the -o <.- polyglycerolated diols corresponding to the formula / j R-jCHOH - CH2-0fCH2-CH0H-CE2-0.?nH j /

Ui · 4 in which R ^ denotes a radical or a mixture of aliphatic, cycloaliphatic or arylaliphatic radicals, the aliphatic chains possibly comprising oxygen or sulfur atoms, n is any number greater than 1 and equal to or less than 10, these compounds are described more particularly in French patent 2,091,516; (vii) hydroxyalkyl polyglycosides comprising an alkyl radical having from 11 to 18 carbon atoms and a number of glycoside units between 3 and 25, these compounds are described more particularly in French patent application 2,397,185, and at least one nonionic polymer chosen from: (i) alkylcelluloses; (ii) polyhydroxyalkylcelluloses; (iii) poly- / to-alanines; (iv) nonionic starch derivatives such as starch hydroxypropyl ethers or hydroxypropylated guar gum derivatives such as for example the products sold under the names JAGUAR HP 60 and JAGUAR HP 8 by the company MEYHALL; (v) natural gums such as tragacanth, arabic, carob gums; (vi) polyvinylpyrrolidone; (vii) polyholosides such as celluloses, starches, dextrins.

The nonionic surfactant as defined above is preferably used in the proportions of 5 to 15% by weight expressed as active material relative to the total weight of the composition.

The nonionic polymers are preferably used in the proportions of between 0.1 and 10% by weight expressed as active material relative to the total weight of the composition.

The alkylcelluloses are chosen more particularly from methyl- and ethylcelluloses and the polyhydroxyalkyl- celluloses are chosen more particularly from /

polyhydroxyethyl-, hydroxypropylmethyl-, or hydroxypropylce ^ tV

5 luloses with a molecular weight between 60,000 and 1,000,000.

The poly- / t> -alanines are more particularly described in Belgian patent application No. 208.516 filed by the applicant.

'. These polymers comprise from 50 to 100% of repeating units of formula; JL CH _ CH _ CO_N J— (I)

I I I

R3 R2 R1 and from 0 to 50% of repeating units of the polyacrylamide type corresponding to the following formula: r- R9 1 2 -j —CH - C - (II) I)

Liu c = o J

Ahr ^^ in which represents a hydrogen atom, or a radical taken from the group consisting of the following radicals: (i) - CH2 -

(ii) - CH20H

(iii) - (CH2), - CHg n 'being 0 or an integer from 1 to 11 r' (iv) - CH - ΙΓ \ r "r1 and r", identical or different, representing a hydrogen atom or an alkyl radical of 1 to 3 carbon atoms? and (v) - (CH2-CH2-0) - ^ - H m being between 1 and 10, and, R2 and R ^ represent a hydrogen atom or a methyl radical.

These polymers are more particularly prepared by polymerization of acrylamide, as described in US Patent 4,082,730. These polymers preferably have a molecular weight between 500 and 100,000 and more particularly between 2000 and 60,000. /// 6

The compositions in accordance with the invention may contain what constitutes another object of the invention of other nonionic surfactants (II) different from the nonionic surfactants (I) mentioned above. These nonionic surfactants (II) are chosen from polyoxyethylenated sorbitol fatty acid esters such as polyoxyethylenated sorbitan monolau-spleen with 20 moles of ethylene oxide or also partial fatty acid esters and oxyethylenated glycerol such as polyoxyethylenated glycerol monolaurate.

These surfactants (II) are known in themselves to be not very aggressive and further lead to the improvement of the properties of the cleaning composition according to the invention.

A preferred embodiment of the invention consists of a cleaning composition containing in particular one of the various non-ionic surfactants (i), (ii), (iii), (iv), (vi) , (vii) mentioned above associated with the nonionic polymers of groups (i) to (vii).

Another preferred embodiment consists of compositions containing the nonionic surfactants defined in paragraphs (i) to (vii) combined with nonionic polymers as defined above and at least one surfactant. non-ionic active (II) chosen from fatty acid esters of polyoxyethylenated sorbitol and partial esters of fatty acid and glycerol oxyethylenated defined above.

The Applicant has discovered in particular that, with the compositions in accordance with the invention, containing the nonionic surfactant (I) (i), (ii), (iii) 7 (iv), (vi) and (vii) above defined with one of the nonionic polymers also defined above in the proportions indicated, better safety was obtained while increasing the detergency. Thus, a composition containing 10% of glucoside alkyl ether sold under the name Triton CG-110-60 has a detergent activity equivalent to 1.25% of sodium lauryl sulfate and a point of half-lysis of 1% while a composition containing 8% of the same / "/

U

7 non-ionic surfactant TRITON CG-110 with hydroxyethylcellulose (0.3%) has a detergent power equivalent to that of a 3% solution of sodium lauryl sulfate and a half-lysis point of 1 , 23%.

The cleaning compositions according to the invention *. can be used for cleaning the skin and hair.

A particularly preferred application is their use for cleaning problem skin such as acne or blackheads.

According to one embodiment, an antiseptic can be added so as to obtain a treating product which can be used in the dermatological field for cleaning wounds, intimate female hygiene, the treatment of eczema and clearly less aggressive than products of this type. already existing on the market.

The antiseptic agents which can be used in this embodiment of the invention are agents known in themselves and commonly used in antiseptic compositions. Mention may be made, for this purpose, of hexamidine diisethionate, 2,4,4'-trichloro-2'-hydroxy-biphenyl ether, chlorhexidine, chlorhexidine digluconate, 4-benzalkonium chloride, 3,4, 4'-trichlorocarbanilide, 8-hydroxyquinoline and its salts, dimethyl alkylbenzylammonium chloride (alkyl is a derivative of coconut fatty acid). These antiseptic agents are present in amounts of between 0.01 and 2.5% by weight relative to the total weight of the composition. :

The compositions in accordance with the invention are generally in the form of aqueous compositions which may optionally contain, depending on the intended application, cosmetically acceptable solvents and have a pH of between 3.5 and 8, for example.

These compositions can in particular be presented when they are used for the treatment of the skin in the form of cream, milk, emulsion, gel, aqueous or hydroalcoholic solution. They also contain adjuvants such as perfumes, dyes, agents / preservatives, thickening agents, drying agents, emulsifiers, sunscreens and any other product well known in the art. 'state of the art and commonly used to form compositions of this type.

The compositions intended for cleaning the hair logo CNRS logo INIST. may be in the form of aqueous or hydroalcoholic solutions, emulsions, creams, milk, gel and possibly be aerosolized with a propellant such as nitrogen, nitrous oxide, fluorochlorinated hydrocarbons of the type Freon or saturated hydrocarbons such as butane or propane.

The examples which follow are intended to illustrate the invention without however being limiting in nature. / é '(♦ * 9 EXAMPLE 1

The following composition was prepared: TRITON CG-110-60 8¾ TWEEN 20 2%

Hydroxyethylcellulose 0.3% ". 0.05% hexamidine diisethionate

Water q.s.p. 100

This composition is used for washing the skin.

The half-lysis point is equal to 1.38% and the composition has a detergency equivalent to 3% of sodium lauryl sulfate.

EXAMPLE 2

The following antiseptic composition is prepared: TRITON CG-110-60 8% in M.A.

TWEEN 20 2%

Hydroxyethylcellulose 0.3%

0.15% hexamidine diisethionate

Irgasan DP 300 0, lO-o

Water and preservative q.s.p. 100

This composition is used for washing the skin and has an antiseptic effect. The half-lysis point of the composition is 1.31% and the composition is equivalent to the detergency test to an aqueous solution of 2.5% of sodium lauryl sulfate.

EXAMPLE 3

The following composition is prepared: TRITON CG-110-60 8% in M.A.

Hydroxyethylcellulose 0.3%

Water q.s.p. 100.

This composition is used for washing the skin.

The half-lysis point is 1.23% while an aqueous composition of sodium lauryl sulphate having the same active ingredient content, that is to say 8.3% has a half-lysis point of 0, 03%.

EXAMPLE 4

The following composition is prepared: / / TRITON CG-110-60 8% in M.A // 10

Poly- / 5-alanine as described in the reference example 15% in M.A.

Water q.s.p. 100

This composition is used for washing the skin. It is found that the half-lysis point is 1.23% of product while a composition having the same active ingredient content, that is to say 13% of sodium lauryl sulfate has a half-lysis point of 0.014%.

EXAMPLE 5

The following composition is prepared: TRITON CG-110-60 5.78 g

Hydroxyethylcellulose 0.22 g

Water q.s.p. 100 /

The half-lysis point of this composition is 1.84% of product. / 1 · / il • / 11 REFERENCE EXAMPLE A Preparation of poly-fb-alanine.

0.15 g of N-phenyl - ^^ apbtyl- is introduced into a 6-liter reactor, fitted with an agitator, a nitrogen inlet and a cooler surmounted by a calcium chloride guard. amine and 2.5 liters of chlorobenzene. The solution is then heated to 80 ° C. and 150 g of acrylamide are added. After complete dissolution of the monomer and return of the reaction mixture at 80 ° C., a hot solution of 3 g of sodium previously dissolved in 300 ml of tert-butanol is added.

A polymer insoluble in the reaction medium quickly forms and is deposited on the walls of the reactor. The reaction is maintained for 8 hours at 80 ° C. At the end of the reaction, the solvent is removed before cooling and the polymer is then dissolved in 1350 ml of water. The solution obtained is adjusted to pH 6 with concentrated hydrochloric acid. The above aqueous phase is washed with 500 ml of chloroform, filtered and concentrated on a rotary evaporator under reduced pressure until 350 g of oily residue is obtained. The pure polymer is obtained by slowly pouring the aqueous concentrate into 15 liters of ethanol with vigorous stirring and then filtering the powder in suspension.

135 g of a white powder are thus obtained after drying, ie a yield of 90%.

/

Viscosity: intrinsic in water at 25 ° C:. / £ n J = 0.121dl / g. ^ *

Claims (13)

12 1. Gentle cleaning composition characterized in that it contains in a cosmetically acceptable medium at least one nonionic surfactant (I) chosen from: (i) the glucoside alkyl ethers corresponding to the formula: ch2oh ^ ch2oh \ £ ü_j) ° γ ~,) ~ '0 ~ R OH OH L OH J (I) in which R denotes an alkyl radical having 8 to 10 carbon atoms, n is 0, 1, 2, 3 or 4; (ii) oxyethylenated or oxypropylenated methylglucosides; (iii) optionally oxyethylenated methylglucoside sesquistearate; (iv) oxyethylenated methylglucoside dioleate; (v) sucrose esters or sucrose esters; ï ivi) polyglycerolated ^ -diols corresponding to the formula: R1CHOH-CH2-OfCH2-CHOH-CH2-OiznH in which R ^ denotes a radical or a mixture of aliphatic, cycloaliphatic or arylaliphatic radicals, the aliphatic chains possibly comprising atoms of oxygen or sulfur, n is any number greater than 1 and equal to or less than 10; (vii) hydroxyalkyl polyglycosides comprising an alkyl radical having 11 to 18 carbon atoms and a number of glycoside units between 3 and 25 or their mixtures; and at least one nonionic polymer chosen from: (i) alkylcelluloses; (ii) polyhydroxyalkylcelluloses; (iii) poly- / i-alanines; (iv) nonionic starch derivatives, hydroxypro-pylated Guar gum derivatives; (v) natural gums such as adra gums. .glove, / f / arabic, of carob; / / (vi) polyvinylpyrrolidone; / / L / f 13 (vii) polyholosides such as celluloses, starches, dextrins; or their mixtures. 2. Composition according to Claim 1, characterized in that the nonionic surfactant (I) is present ", in the proportions of between 5 and 15% expressed as active material relative to the total weight of the composition and that the nonionic polymers are present in the proportions of between 0.1 and 10% by weight relative to the total weight of the composition. 3 I NHR1 in which represents a hydrogen atom, or a radical taken from the group consisting of the following radicals: (i) - CH2 - l · / (ii) - CH2OH (iii) - (CH2) n, —CH ^ n1 being 0 or an integer from 1 to 11 r1 (iv) - CH „—N ^ 2 \ r" r 'and r ", identical or different, representing a hydrogen atom or an alkyl radical from 1 to 3 carbon atoms and (v) - (CH2-CH2-0) - ^ - H m being between 1 and 10, and, R ^ and R ^ represent a hydrogen atom or a methyl radical. 3. Composition according to claim 1 or 2, characterized in that the nonionic surfactant (I) is chosen from compounds (i), (ii), (iii), (iv), (vi) and (vii) defined in claim 1. 4. Composition according to claim 1 or 2, characterized in that it also contains other nonionic surfactants other than those defined in claim 1. 5. Composition according to claim 4, characterized in that the additional nonionic surfactant (II) is chosen from polyoxyethylenated sorbitol fatty acid esters or partial polyoxyethylenated glycerol fatty acid esters . 6. Composition according to any one of claims 1 to 5, characterized in that the alkylcelluloses are chosen from methyl and ethylcelluloses, that the poly-hydroxyalkylcelluloses are chosen from polyhydroxyethyl-, polyhydroxypropylmethyl-, and polyhydroxypropylcelluloses having a weight molecular between 60,000 and 1,000,000. 7. Composition according to any one of claims 1 to 5, characterized in that the poly- / 2> -alanines are chosen from polymers comprising from 50 to 100% of repeating units of formula corresponding to the formula: —CH - CH — CO — N— | - Il I * 3 R2 V (I) / and from 0 to 50% of repeating units of formula \ rj 14 r R? π I 2 --CH - C - (II) l I R0 C = 0_ 8. Composition according to any one of claims 1 to 7, characterized in that it contains between 0.01 and 2.5% of an antiseptic agent. 9. Composition according to any one of claims 1 to 7, characterized in that the antiseptic agent is chosen from hexamidine diisethionate, 2,4,4'-tri-chloro-2'-hydroxybiphenyl ether, chlorhexidine, chlorhexidine digluconate, 4-benzalkonium chloride, 3,4,4'-trichlorocarbanilide, 8-hydroxyquinoline and its salts, dimethyl alkyl benzylammonium chloride in leguel the alkyl group denotes a derivative of copra fatty acid. 10. Composition according to any one of claims 1 to 8, characterized in that it is in the form of an aqueous, hydroalcoholic solution, cream, milk, gel, emulsion optionally packaged in aerosol enj 15 11. Use of the composition as defined in any one of claims 1 to 10, for cleaning acne or blackhead skin. 12. Cleaning composition intended for cleaning wounds, characterized in that it has the composition as defined in claims 1 to 10. 13. Composition intended to be used in the treatment of dermatological diseases such as eczema, characterized in that it has the composition as defined in any one of claims 1 to 10. Drawings: _________ Z .... plates ..... pages of which ......... Λ ...... cover page ......... d ± ... description pages! ............ claims pages abridged description Luxembourg, le. . r.nT, nD,. ^ 1 I übi, laüL The representative: Vy '--------- C- ^ £ xjÊ * u, Charles München