LU79477A1 - Procedes de preparation de l'antigene du noyau d'hepatite b et de vaccins le contenant - Google Patents

Procedes de preparation de l'antigene du noyau d'hepatite b et de vaccins le contenant

Info

Publication number
LU79477A1
LU79477A1 LU79477A LU79477A LU79477A1 LU 79477 A1 LU79477 A1 LU 79477A1 LU 79477 A LU79477 A LU 79477A LU 79477 A LU79477 A LU 79477A LU 79477 A1 LU79477 A1 LU 79477A1
Authority
LU
Luxembourg
Prior art keywords
hepatitis
antigen
preparing
core
methods
Prior art date
Application number
LU79477A
Other languages
English (en)
French (fr)
Inventor
W Mcaleer
W Miller
E Wasmuth
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of LU79477A1 publication Critical patent/LU79477A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G01N33/5762—Hepatitis B core antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LU79477A 1977-04-20 1978-04-20 Procedes de preparation de l'antigene du noyau d'hepatite b et de vaccins le contenant LU79477A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/789,033 US4102996A (en) 1977-04-20 1977-04-20 Method of preparing hepatitis B core antigen

Publications (1)

Publication Number Publication Date
LU79477A1 true LU79477A1 (fr) 1978-11-28

Family

ID=25146371

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79477A LU79477A1 (fr) 1977-04-20 1978-04-20 Procedes de preparation de l'antigene du noyau d'hepatite b et de vaccins le contenant

Country Status (14)

Country Link
US (1) US4102996A (de)
JP (4) JPS53133628A (de)
BE (1) BE866096A (de)
CA (1) CA1106279A (de)
DE (1) DE2816864C2 (de)
DK (1) DK158678C (de)
FR (1) FR2387656A1 (de)
GB (3) GB1596591A (de)
HK (3) HK67684A (de)
IE (1) IE46793B1 (de)
IT (1) IT1102573B (de)
LU (1) LU79477A1 (de)
NL (1) NL7803625A (de)
SG (1) SG41884G (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2750045A1 (de) * 1977-11-09 1979-05-10 Behringwerke Ag Verfahren zur entfernung von detergentien aus virusantigensuspensionen
US4204989A (en) * 1978-12-13 1980-05-27 Merck & Co., Inc. Isolation of hepatitis B e antigen
US4241175A (en) * 1978-12-18 1980-12-23 Merck & Co., Inc. Assay for hepatitis B core antibody
LU88257I2 (de) * 1978-12-22 1994-02-03
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
US4395395A (en) * 1979-05-21 1983-07-26 The United States Of America As Represented By The Department Of Health And Human Services Detection of non-A, non-B hepatitis associated antigen
CA1148859A (en) * 1979-06-14 1983-06-28 Lacy R. Overby Simultaneous assay of two hepatitis viruses using a solid phase
FR2470795A1 (fr) * 1979-12-07 1981-06-12 Pasteur Institut Procede de purification de particules d'origine biologique, notamment de l'antigene de surface du virus de l'hepatite b (aghbs) et les produits obtenus
JPH0625069B2 (ja) * 1981-01-29 1994-04-06 ブリティッシュ・テクノロジー・グループ・リミテッド Ｂ型肝炎ワクチン製造方法
AU8746582A (en) * 1981-09-02 1983-03-10 Biogen N.V. Hepatitis b virus e type antigen
US4721675A (en) * 1982-02-01 1988-01-26 Abbott Laboratories Production of hepatitis A virus in vitro utilizing a persistently virus infected cell culture system
EP0121303B1 (de) * 1983-03-04 1989-07-26 Noctech Limited Diagnostisches Agens, Verfahren zur Herstellung desselben und seine Verwendung in diagnostischen Verfahren
US4547367A (en) * 1983-12-20 1985-10-15 The United States Of America As Represented By The Department Of Health And Human Services Hepatitis B core antigen vaccine
US4547368A (en) * 1983-12-20 1985-10-15 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitis B core antigen vaccine made by recombinant DNA
JPS60197629A (ja) * 1984-03-16 1985-10-07 Chemo Sero Therapeut Res Inst ＨＢｓ抗原の精製方法
JPS60258127A (ja) * 1984-06-04 1985-12-20 Green Cross Corp:The Ｂ型肝炎ワクチンの製造方法
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
US4649192A (en) * 1985-05-30 1987-03-10 Smith Kline-Rit Method for the isolation and purification of hepatitis B surface antigen using polysorbate
DE3604947A1 (de) * 1986-02-17 1987-08-20 Biotest Pharma Gmbh Verfahren zur herstellung eines immunglobulinhaltigen praeparates und dessen verwendung zur prophylaxe und therapie von aids
EP0341439B1 (de) * 1988-05-11 1993-08-04 Abbott Laboratories Verfahren zur Erhöhung der Spezifizität in kompetitiven Immuntests
BR0205774A (pt) * 2002-02-27 2004-04-20 Fundacao De Amparo A Pesquisa Sistema adjuvante para produção de anticorpos, vacina e uso

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636191A (en) * 1969-10-08 1972-01-18 Cancer Res Inst Vaccine against viral hepatitis and process
SE437329B (sv) * 1975-03-14 1985-02-25 Community Blood Council Sett att ur blodserum framstella vaccin mot virushepatit
GB1518582A (en) * 1975-11-17 1978-07-19 Community Blood Council Viral hepatitis vaccine
DE2611723C3 (de) * 1976-03-19 1978-09-21 The Green Cross Corp., Osaka (Japan) Verfahren zur Herstellung von einheitlichen kugelförmigen HBsAg-Teilchen
NL7711378A (nl) * 1976-11-02 1978-05-05 Merck & Co Inc Werkwijze voor het bereiden van preparaten die dane-deeltjes bevatten.

Also Published As

Publication number Publication date
DE2816864A1 (de) 1978-10-26
SG41884G (en) 1985-03-08
FR2387656A1 (fr) 1978-11-17
JPS57201854A (en) 1982-12-10
DK171178A (da) 1978-10-21
GB1596593A (en) 1981-08-26
JPS53133628A (en) 1978-11-21
DE2816864C2 (de) 1985-08-14
GB1596591A (en) 1981-08-26
JPS57203016A (en) 1982-12-13
FR2387656B1 (de) 1982-02-19
HK67784A (en) 1984-09-07
DK158678C (da) 1990-12-31
US4102996A (en) 1978-07-25
IE46793B1 (en) 1983-09-21
JPS58180430A (ja) 1983-10-21
CA1106279A (en) 1981-08-04
NL7803625A (nl) 1978-10-24
HK67684A (en) 1984-09-07
DK158678B (da) 1990-07-02
HK67584A (en) 1984-09-07
IT1102573B (it) 1985-10-07
GB1596592A (en) 1981-08-26
IT7848873A0 (it) 1978-04-12
BE866096A (fr) 1978-10-18
IE780716L (en) 1978-10-20
JPS6141897B2 (de) 1986-09-18

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