LTIP575A - Method for preparing 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo[4,3,0]nonane - Google Patents
Method for preparing 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo[4,3,0]nonaneInfo
- Publication number
- LTIP575A LTIP575A LTIP575A LTIP575A LTIP575A LT IP575 A LTIP575 A LT IP575A LT IP575 A LTIP575 A LT IP575A LT IP575 A LTIP575 A LT IP575A LT IP575 A LTIP575 A LT IP575A
- Authority
- LT
- Lithuania
- Prior art keywords
- nonane
- trimethyl
- oxo
- dichloroacetyl
- diazabicyclo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Abstract
The manufacture of 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo[4.3.0]-nonane I by the reaction of 3,3,6-trimethyl-9-oxo-1,5-diaza-bicyclo[4.3.0]nonane II with dichloroacetyl chloride in the presence of a solvent and a base, wherein a) this reaction is carried out in a two-phase system comprising a virtually water-insoluble organic solvent and water, and sodium or potassium hydroxide acting as the base is metered in at a rate corresponding to the rate of consumption of the dichloroacetyl chloride such that the aqueous phase exhibits a pH of from 7 to 9, and b) the resulting product is separated.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4217846A DE4217846C1 (en) | 1992-05-29 | 1992-05-29 | Process for the preparation of 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo [4,3,0] nonane |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LTIP575A true LTIP575A (en) | 1994-04-25 |
| LT3016B LT3016B (en) | 1994-08-25 |
Family
ID=6460024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTIP575A LT3016B (en) | 1992-05-29 | 1993-05-28 | Method for preparing 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo(4,3, 0)nonane |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5677452A (en) |
| EP (1) | EP0642511B1 (en) |
| AT (1) | ATE142210T1 (en) |
| AU (1) | AU4313293A (en) |
| CA (1) | CA2136872C (en) |
| CZ (1) | CZ276094A3 (en) |
| DE (2) | DE4217846C1 (en) |
| ES (1) | ES2091007T3 (en) |
| HU (1) | HU213833B (en) |
| LT (1) | LT3016B (en) |
| LV (1) | LV11036B (en) |
| PL (1) | PL173088B1 (en) |
| RU (1) | RU94046203A (en) |
| SK (1) | SK142894A3 (en) |
| WO (1) | WO1993024489A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6476046B1 (en) | 2000-12-04 | 2002-11-05 | Sepracor, Inc. | Diazabicyclo[4.3.0]nonanes, and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1802468A1 (en) | 1968-10-11 | 1970-05-21 | Bayer Ag | Diazabicycloalkanes, plant protection agents |
| DE2948535A1 (en) * | 1979-12-03 | 1981-06-25 | Basf Ag, 6700 Ludwigshafen | DICHLORACETAMIDES, HERBICIDE AGENTS THAT CONTAIN ACETANILIDES AS HERBICIDAL ACTIVE SUBSTANCES AND THESE DICHLORACETAMIDES AS AN ANTAGONISTIC AGENTS, AND THEIR USE FOR CONTROLLING UNWANTED PLANT GROWTH |
| EP0190105A3 (en) * | 1985-01-31 | 1988-10-26 | Ciba-Geigy Ag | Herbicidal agent |
| US4995899A (en) * | 1986-01-15 | 1991-02-26 | Basf Aktiengesellschaft | Optically active diazabicycloalkane derivatives and their use for protecting crops from the phytotoxic effect of herbicides |
| DE3600903A1 (en) * | 1986-01-15 | 1987-07-16 | Basf Ag | OPTICALLY ACTIVE DIAZABICYCLOAL CANDERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR PROTECTING CULTURAL PLANTS FROM THE PHYTOTOXIC EFFECT OF HERBICIDES |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
-
1992
- 1992-05-29 DE DE4217846A patent/DE4217846C1/en not_active Expired - Lifetime
-
1993
- 1993-05-18 SK SK1428-94A patent/SK142894A3/en unknown
- 1993-05-18 AU AU43132/93A patent/AU4313293A/en not_active Abandoned
- 1993-05-18 ES ES93912713T patent/ES2091007T3/en not_active Expired - Lifetime
- 1993-05-18 CZ CZ942760A patent/CZ276094A3/en unknown
- 1993-05-18 DE DE59303673T patent/DE59303673D1/en not_active Expired - Lifetime
- 1993-05-18 EP EP93912713A patent/EP0642511B1/en not_active Expired - Lifetime
- 1993-05-18 PL PL93306379A patent/PL173088B1/en not_active IP Right Cessation
- 1993-05-18 WO PCT/EP1993/001234 patent/WO1993024489A1/en not_active Application Discontinuation
- 1993-05-18 RU RU94046203/04A patent/RU94046203A/en unknown
- 1993-05-18 CA CA002136872A patent/CA2136872C/en not_active Expired - Fee Related
- 1993-05-18 HU HU9403409A patent/HU213833B/en not_active IP Right Cessation
- 1993-05-18 AT AT93912713T patent/ATE142210T1/en not_active IP Right Cessation
- 1993-05-27 LV LVP-93-432A patent/LV11036B/en unknown
- 1993-05-28 LT LTIP575A patent/LT3016B/en not_active IP Right Cessation
-
1996
- 1996-10-24 US US08/736,438 patent/US5677452A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE4217846C1 (en) | 1993-12-23 |
| US5677452A (en) | 1997-10-14 |
| ES2091007T3 (en) | 1996-10-16 |
| HUT69060A (en) | 1995-08-28 |
| HU213833B (en) | 1997-10-28 |
| LV11036A (en) | 1996-02-20 |
| SK142894A3 (en) | 1995-06-07 |
| WO1993024489A1 (en) | 1993-12-09 |
| RU94046203A (en) | 1996-09-27 |
| LV11036B (en) | 1996-06-20 |
| LT3016B (en) | 1994-08-25 |
| ATE142210T1 (en) | 1996-09-15 |
| CA2136872C (en) | 2004-01-20 |
| CZ276094A3 (en) | 1995-02-15 |
| DE59303673D1 (en) | 1996-10-10 |
| HU9403409D0 (en) | 1995-03-28 |
| EP0642511A1 (en) | 1995-03-15 |
| EP0642511B1 (en) | 1996-09-04 |
| CA2136872A1 (en) | 1993-05-18 |
| AU4313293A (en) | 1993-12-30 |
| PL173088B1 (en) | 1998-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9A | Lapsed patents |
Effective date: 19990528 |