LTIP177A - Farmacinė medžiaga ir jos gamybos būdas - Google Patents
Farmacinė medžiaga ir jos gamybos būdasInfo
- Publication number
- LTIP177A LTIP177A LTIP177A LTIP177A LTIP177A LT IP177 A LTIP177 A LT IP177A LT IP177 A LTIP177 A LT IP177A LT IP177 A LTIP177 A LT IP177A LT IP177 A LTIP177 A LT IP177A
- Authority
- LT
- Lithuania
- Prior art keywords
- preparation
- pharmaceutical composition
- diethoxybenzyl
- dihydroisoquinoline
- diethoxy
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- NCVXEYAKRVJMTQ-UHFFFAOYSA-N 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline Chemical compound C1=C(OCC)C(OCC)=CC=C1CC1=NCCC2=CC(OCC)=C(OCC)C=C12 NCVXEYAKRVJMTQ-UHFFFAOYSA-N 0.000 abstract 1
- HCYFGRCYSCXKNQ-UHFFFAOYSA-M 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetate Chemical compound O=C1N(C)C(=O)N(C)C2=C1N(CC([O-])=O)C=N2 HCYFGRCYSCXKNQ-UHFFFAOYSA-M 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 abstract 1
- 229960001123 epoprostenol Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000004682 monohydrates Chemical class 0.000 abstract 1
- XQYZDYMELSJDRZ-UHFFFAOYSA-N papaverine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=NC=CC2=CC(OC)=C(OC)C=C12 XQYZDYMELSJDRZ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Išradimas yra apie 1-(3',4'-dimetoksibenzil)-6,7-dimetoksiizochinolino, arba 1-(3',4'-dietoksibenzil)-6,7-dietoksi-3,4-dihidroizochinolino, arba(3',4'-dietoksibenzil)-6,7-dietoksi-3,4-dihidroizochinolino teofilin-7-acetato ar jų monohidrato, kaip veikliųjų sudėtinių dalių, panaudojimą gaminant medikamentus, kurie vartojami gydymui ar apsaugai nuo sąlygų, susidarančių dėl padidinto trombocitų sulipimo aktyvumo, sumažėjus prostaciklino atpalaidavimui.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU911198A HUT60926A (en) | 1991-04-12 | 1991-04-12 | Process for producing pharmaceutical composition suitable for reducing or preventing increased thrombocyte-aggregation capability |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LTIP177A true LTIP177A (lt) | 1994-03-25 |
| LT3045B LT3045B (en) | 1994-09-25 |
Family
ID=10953302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTIP177A LT3045B (en) | 1991-04-12 | 1992-08-28 | Pharmaceutical composition and process for the preparation thereof |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0513997A1 (lt) |
| JP (1) | JPH06145058A (lt) |
| KR (1) | KR950013757B1 (lt) |
| AU (1) | AU1482292A (lt) |
| CA (1) | CA2065689A1 (lt) |
| HU (1) | HUT60926A (lt) |
| LT (1) | LT3045B (lt) |
| LV (1) | LV10049A (lt) |
| ZA (1) | ZA922354B (lt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3276762B2 (ja) * | 1993-12-28 | 2002-04-22 | 日本臓器製薬株式会社 | イソキノリン誘導体を含有する医薬組成物 |
| HUT71408A (en) * | 1994-01-14 | 1995-11-28 | Egyt Gyogyszervegyeszeti Gyar | Pharmaceutical compositions containing papaverine for use to treatment of diseases related to glutamaterg neurotransmission |
| EP2014651A1 (en) * | 2007-07-12 | 2009-01-14 | Exonhit Therapeutics SA | Compounds and methods for modulating Rho GTPases |
| BR112013029621A2 (pt) * | 2011-05-20 | 2016-12-13 | Chinoin Private Co Ltd | composição farmacêutica que compreende drotaverine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3035366A (en) | 1959-08-17 | 1962-05-22 | Frank J Luketa | Trawl net panel assembly |
| HU167246B (lt) | 1973-01-25 | 1975-09-27 | ||
| HU171731B (hu) | 1975-12-12 | 1978-03-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija papaverina |
| HU194179B (en) | 1985-10-03 | 1988-01-28 | Chinoin Gyogyszer Es Vegyeszet | Process for production of 1-/3',4'-dietoxi-benzil/-1,6,7-dietoxi-3,4-dihydro-izoquinolinine-teophilin-7-acetate and their new cristallic monohydrate |
| HU197207B (en) * | 1985-12-04 | 1989-03-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical comprising 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydro-isoquinolinium-theophylline-7-acetate or its monohydrate as active ingredient |
-
1991
- 1991-04-12 HU HU911198A patent/HUT60926A/hu unknown
-
1992
- 1992-03-31 ZA ZA922354A patent/ZA922354B/xx unknown
- 1992-04-09 LV LV920006A patent/LV10049A/xx unknown
- 1992-04-09 CA CA002065689A patent/CA2065689A1/en not_active Abandoned
- 1992-04-10 EP EP92303207A patent/EP0513997A1/en not_active Withdrawn
- 1992-04-10 AU AU14822/92A patent/AU1482292A/en not_active Abandoned
- 1992-04-10 KR KR1019920006016A patent/KR950013757B1/ko not_active Expired - Lifetime
- 1992-04-10 JP JP4135534A patent/JPH06145058A/ja active Pending
- 1992-08-28 LT LTIP177A patent/LT3045B/lt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR920019356A (ko) | 1992-11-19 |
| JPH06145058A (ja) | 1994-05-24 |
| CA2065689A1 (en) | 1992-10-13 |
| EP0513997A1 (en) | 1992-11-19 |
| LT3045B (en) | 1994-09-25 |
| AU1482292A (en) | 1992-10-15 |
| KR950013757B1 (ko) | 1995-11-15 |
| LV10049A (lv) | 1994-05-10 |
| HU911198D0 (en) | 1991-10-28 |
| ZA922354B (en) | 1993-02-24 |
| HUT60926A (en) | 1992-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM9A | Lapsed patents |
Effective date: 19950828 |