ZA914376B - Benzimidazole derivatives,their preparation process,the intermediates obtained,their use as medicaments and the pharmaceutical compositions containing them - Google Patents
Benzimidazole derivatives,their preparation process,the intermediates obtained,their use as medicaments and the pharmaceutical compositions containing themInfo
- Publication number
- ZA914376B ZA914376B ZA914376A ZA914376A ZA914376B ZA 914376 B ZA914376 B ZA 914376B ZA 914376 A ZA914376 A ZA 914376A ZA 914376 A ZA914376 A ZA 914376A ZA 914376 B ZA914376 B ZA 914376B
- Authority
- ZA
- South Africa
- Prior art keywords
- medicaments
- pharmaceutical compositions
- preparation process
- compositions containing
- benzimidazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/40—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR909007135A FR2663028B1 (en) | 1990-06-08 | 1990-06-08 | NOVEL BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA914376B true ZA914376B (en) | 1992-08-26 |
Family
ID=9397404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA914376A ZA914376B (en) | 1990-06-08 | 1991-06-07 | Benzimidazole derivatives,their preparation process,the intermediates obtained,their use as medicaments and the pharmaceutical compositions containing them |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN1045771C (en) |
FR (1) | FR2663028B1 (en) |
ZA (1) | ZA914376B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3501484B2 (en) * | 1992-12-17 | 2004-03-02 | 三共株式会社 | Biphenyl derivative |
CN102276585B (en) * | 2010-06-09 | 2013-06-19 | 中国药科大学 | Preparation method for and medicinal usage of 4-substituted-phenyl-aryl-carboxylate derivatives |
CN111116484B (en) * | 2019-12-24 | 2022-11-11 | 山西大学 | Preparation method of 5,6-bis (4-aminobenzyl) -1,2 dimethyl-benzimidazole |
CN111057011B (en) * | 2019-12-24 | 2022-11-11 | 山西大学 | Preparation method of 5, 6-bis (4-aminobenzyl) -1-methyl-2-phenylbenzimidazole |
CN111116485B (en) * | 2019-12-24 | 2022-11-11 | 山西大学 | Preparation method of 5, 6-bis (4-aminobenzyl) -2-trifluoromethyl-1H-benzimidazole |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61151176A (en) * | 1984-12-24 | 1986-07-09 | Sumitomo Chem Co Ltd | Benzimidazole derivative, production thereof, insecticide and acaricide comprising same as active ingredient |
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
NZ221729A (en) * | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
-
1990
- 1990-06-08 FR FR909007135A patent/FR2663028B1/en not_active Expired - Fee Related
-
1991
- 1991-06-07 ZA ZA914376A patent/ZA914376B/en unknown
- 1991-06-08 CN CN91103858A patent/CN1045771C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1057256A (en) | 1991-12-25 |
FR2663028B1 (en) | 1994-10-14 |
FR2663028A1 (en) | 1991-12-13 |
CN1045771C (en) | 1999-10-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU7820191A (en) | New imidazole derivatives, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them | |
GB9506856D0 (en) | New erythromycin derivatives,processes for preparing them,the products thus prepared,pharmaceutical compositions containing them,and their use as medicaments | |
IL99225A0 (en) | 3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them | |
HUT46654A (en) | Process for producing substituted basic 2-amino-tetralin derivatives and pharmaceutical compositions comprising the same as active ingredient | |
IL98472A0 (en) | Dialkoxy-pyridinyl-benzimidazole derivatives,process for their preparation and their pharmaceutical use | |
IL92798A0 (en) | Benzimidazole derivatives,process for their preparation and pharmaceutical compositions containing them | |
IL100262A0 (en) | Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them | |
AP9100285A0 (en) | Substituted benzimidazoles,process for their preparation and their pharmaceutical use | |
IL97050A0 (en) | 4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation | |
IL98542A0 (en) | Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them | |
ZA9557B (en) | Optionally substituted phenylimidazolidines their preparation process and intermediates their use as medicaments and the pharmaceutical compositions containing them | |
CS299991A3 (en) | Derivatives of 2-aminopyrimidine-4-carboxamide, process of their preparation and their application as medicaments | |
ZA80234B (en) | New heterotricyclic derivatives, process for their preparation, their use as medicaments and the pharmaceutical compositions incorporating them | |
EP0258096A3 (en) | Indane derivatives, process for their preparation, their use as medicines, pharmaceutical compositions containing them and the intermediates obtained | |
GR3002264T3 (en) | Decahydroquinoline derivatives, method for their preparation and intermediates thereof, their use as medicaments and their pharmaceutical compositions | |
ZA902866B (en) | Substituted azetidinylisothiazolopyridone derivatives,their preparation and their application as medicinal products | |
ZA914376B (en) | Benzimidazole derivatives,their preparation process,the intermediates obtained,their use as medicaments and the pharmaceutical compositions containing them | |
AU660296B2 (en) | Pharmaceutical compositions containing functionalized vinylazoles, use of these vinylazoles for producing medicaments, these vinylazoles themselves and process for producing the same | |
CS235091A3 (en) | Novel derivatives of 1-diphenylmethylpiperazine, process of their preparation and their application as medicaments | |
IL104347A0 (en) | Substituted benzimidazole derivatives,their preparation and pharmaceutical compositions containing them | |
ZA968762B (en) | Derivatives of acid pyrazoles, their preparation process, their use as medicaments, their new use and the pharmaceutical compositions containing them. | |
IL87209A0 (en) | Benzimidazole derivatives,their manufacture and pharmaceutical compositions containing them | |
ZA912975B (en) | Serotonin-antagonist naphthosultam derivatives,their preparation and pharmaceutical compositions containing them | |
IL97321A0 (en) | Diamine derivatives,their manufacture and pharmaceutical compositions containing them | |
IL95760A0 (en) | Imidazole derivatives,their preparation and pharmaceutical compositions containing the same |