LTIP177A - Pharmaceutical composition and process for the preparation thereof - Google Patents

Pharmaceutical composition and process for the preparation thereof

Info

Publication number
LTIP177A
LTIP177A LTIP177A LTIP177A LTIP177A LT IP177 A LTIP177 A LT IP177A LT IP177 A LTIP177 A LT IP177A LT IP177 A LTIP177 A LT IP177A LT IP177 A LTIP177 A LT IP177A
Authority
LT
Lithuania
Prior art keywords
preparation
pharmaceutical composition
diethoxybenzyl
dihydroisoquinoline
diethoxy
Prior art date
Application number
LTIP177A
Other languages
Lithuanian (lt)
Inventor
Zoltan Kapui
Istvan Hermecz
Laszlo Tardos
Katalin Marmarosi
Lelle Vasvari
Agnes Horvath
Original Assignee
Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt filed Critical Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt
Publication of LTIP177A publication Critical patent/LTIP177A/en
Publication of LT3045B publication Critical patent/LT3045B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Išradimas yra apie 1-(3',4'-dimetoksibenzil)-6,7-dimetoksiizochinolino, arba 1-(3',4'-dietoksibenzil)-6,7-dietoksi-3,4-dihidroizochinolino, arba(3',4'-dietoksibenzil)-6,7-dietoksi-3,4-dihidroizochinolino teofilin-7-acetato ar jų monohidrato, kaip veikliųjų sudėtinių dalių, panaudojimą gaminant medikamentus, kurie vartojami gydymui ar apsaugai nuo sąlygų, susidarančių dėl padidinto trombocitų sulipimo aktyvumo, sumažėjus prostaciklino atpalaidavimui.The invention relates to 1- (3 ', 4'-dimethoxybenzyl) -6,7-dimethoxyisoquinoline, or 1- (3', 4'-diethoxybenzyl) -6,7-diethoxy-3,4-dihydroisoquinoline, or (3 ') The use of 4'-diethoxybenzyl) -6,7-diethoxy-3,4-dihydroisoquinoline theophylline-7-acetate or their monohydrate as active ingredients in the manufacture of medicaments for treatment or protection against conditions resulting from increased platelet adhesion activity by reducing the release of prostacyclin.

LTIP177A 1991-04-12 1992-08-28 Pharmaceutical composition and process for the preparation thereof LT3045B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU911198A HUT60926A (en) 1991-04-12 1991-04-12 Process for producing pharmaceutical composition suitable for reducing or preventing increased thrombocyte-aggregation capability

Publications (2)

Publication Number Publication Date
LTIP177A true LTIP177A (en) 1994-03-25
LT3045B LT3045B (en) 1994-09-25

Family

ID=10953302

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP177A LT3045B (en) 1991-04-12 1992-08-28 Pharmaceutical composition and process for the preparation thereof

Country Status (9)

Country Link
EP (1) EP0513997A1 (en)
JP (1) JPH06145058A (en)
KR (1) KR950013757B1 (en)
AU (1) AU1482292A (en)
CA (1) CA2065689A1 (en)
HU (1) HUT60926A (en)
LT (1) LT3045B (en)
LV (1) LV10049A (en)
ZA (1) ZA922354B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3276762B2 (en) * 1993-12-28 2002-04-22 日本臓器製薬株式会社 Pharmaceutical composition containing isoquinoline derivative
HUT71408A (en) * 1994-01-14 1995-11-28 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical compositions containing papaverine for use to treatment of diseases related to glutamaterg neurotransmission
EP2014651A1 (en) * 2007-07-12 2009-01-14 Exonhit Therapeutics SA Compounds and methods for modulating Rho GTPases
PL2709599T3 (en) * 2011-05-20 2018-07-31 Chinoin Private Co Ltd Pharmaceutical composition comprising drotaverine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3035366A (en) 1959-08-17 1962-05-22 Frank J Luketa Trawl net panel assembly
HU167246B (en) 1973-01-25 1975-09-27
HU171731B (en) 1975-12-12 1978-03-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing papaverine
HU194179B (en) 1985-10-03 1988-01-28 Chinoin Gyogyszer Es Vegyeszet Process for production of 1-/3',4'-dietoxi-benzil/-1,6,7-dietoxi-3,4-dihydro-izoquinolinine-teophilin-7-acetate and their new cristallic monohydrate
HU197207B (en) * 1985-12-04 1989-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical comprising 1-(3',4'-diethoxybenzyl)-6,7-diethoxy-3,4-dihydro-isoquinolinium-theophylline-7-acetate or its monohydrate as active ingredient

Also Published As

Publication number Publication date
EP0513997A1 (en) 1992-11-19
KR950013757B1 (en) 1995-11-15
AU1482292A (en) 1992-10-15
KR920019356A (en) 1992-11-19
CA2065689A1 (en) 1992-10-13
ZA922354B (en) 1993-02-24
JPH06145058A (en) 1994-05-24
HUT60926A (en) 1992-11-30
LV10049A (en) 1994-05-10
LT3045B (en) 1994-09-25
HU911198D0 (en) 1991-10-28

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Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 19950828