LT3441389T - Pirazol-oksazolidinono junginys prieš hepatito b virusą - Google Patents

Pirazol-oksazolidinono junginys prieš hepatito b virusą

Info

Publication number
LT3441389T
LT3441389T LTEPPCT/CN2017/079552T LTCN2017079552T LT3441389T LT 3441389 T LT3441389 T LT 3441389T LT CN2017079552 T LTCN2017079552 T LT CN2017079552T LT 3441389 T LT3441389 T LT 3441389T
Authority
LT
Lithuania
Prior art keywords
pyrazole
hepatitis
virus
oxazolidinone compound
oxazolidinone
Prior art date
Application number
LTEPPCT/CN2017/079552T
Other languages
English (en)
Inventor
Huanming Chen
Original Assignee
Shanghai Zhimeng Biopharma, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Zhimeng Biopharma, Inc. filed Critical Shanghai Zhimeng Biopharma, Inc.
Publication of LT3441389T publication Critical patent/LT3441389T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEPPCT/CN2017/079552T 2016-04-06 2017-04-06 Pirazol-oksazolidinono junginys prieš hepatito b virusą LT3441389T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610210422 2016-04-06
PCT/CN2017/079552 WO2017173999A1 (zh) 2016-04-06 2017-04-06 抗乙肝病毒的吡唑-噁唑烷酮类化合物

Publications (1)

Publication Number Publication Date
LT3441389T true LT3441389T (lt) 2021-10-11

Family

ID=60000897

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/CN2017/079552T LT3441389T (lt) 2016-04-06 2017-04-06 Pirazol-oksazolidinono junginys prieš hepatito b virusą

Country Status (15)

Country Link
US (1) US10519145B2 (lt)
EP (1) EP3441389B1 (lt)
JP (1) JP6581745B2 (lt)
KR (1) KR102083818B1 (lt)
CN (1) CN109311865B (lt)
CY (1) CY1124671T1 (lt)
DK (1) DK3441389T3 (lt)
ES (1) ES2893208T3 (lt)
HR (1) HRP20211907T1 (lt)
LT (1) LT3441389T (lt)
PL (1) PL3441389T3 (lt)
PT (1) PT3441389T (lt)
RS (1) RS62597B1 (lt)
SI (1) SI3441389T1 (lt)
WO (1) WO2017173999A1 (lt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202111236UA (en) 2019-04-30 2021-11-29 Aicuris Gmbh & Co Kg Novel indole-2-carboxamides active against the hepatitis b virus (hbv)
SG11202111493WA (en) 2019-04-30 2021-11-29 Aicuris Gmbh & Co Kg Novel oxalyl piperazines active against the hepatitis b virus (hbv)
US20220227789A1 (en) 2019-04-30 2022-07-21 Aicuris Gmbh & Co. Kg Novel indolizine-2-carboxamides active against the hepatitis b virus (hbv)
EP3962912A1 (en) 2019-04-30 2022-03-09 AiCuris GmbH & Co. KG Novel phenyl and pyridyl ureas active against the hepatitis b virus (hbv)
CN112574188B (zh) * 2019-09-29 2022-05-06 苏州爱科百发生物医药技术有限公司 一种吡唑类化合物及其应用
WO2022135601A1 (zh) * 2020-12-25 2022-06-30 杭州百新生物医药科技有限公司 5-烷基-2-吡唑-恶唑烷-4-酮类衍生物及其用途
CN115677680A (zh) * 2021-07-23 2023-02-03 上海挚盟医药科技有限公司 式i化合物的晶型及其制备和应用
CN115677681A (zh) * 2021-07-23 2023-02-03 上海挚盟医药科技有限公司 一种乙肝病毒核衣壳抑制剂的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006033995A2 (en) * 2004-09-16 2006-03-30 Valeant Research And Development Thiazolidin-4-ones having anti-hepatitis b activity
WO2007014023A1 (en) 2005-07-21 2007-02-01 Valeant Research & Development Thiazolidinones, oxazolidinones, and pyrrolidinones for hbv

Also Published As

Publication number Publication date
ES2893208T3 (es) 2022-02-08
EP3441389A1 (en) 2019-02-13
PT3441389T (pt) 2021-11-11
DK3441389T3 (da) 2021-11-08
RS62597B1 (sr) 2021-12-31
CY1124671T1 (el) 2022-07-22
JP6581745B2 (ja) 2019-09-25
SI3441389T1 (sl) 2022-01-31
KR102083818B1 (ko) 2020-03-03
US20190152963A1 (en) 2019-05-23
US10519145B2 (en) 2019-12-31
JP2019513830A (ja) 2019-05-30
EP3441389B1 (en) 2021-09-08
PL3441389T3 (pl) 2022-01-24
HRP20211907T1 (hr) 2022-03-18
CN109311865A (zh) 2019-02-05
EP3441389A4 (en) 2019-09-04
KR20180128953A (ko) 2018-12-04
WO2017173999A1 (zh) 2017-10-12
CN109311865B (zh) 2021-08-31

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