LT3098239T - Į egfr nukreipiamas dvigrandis rnr vektorius, skirtas sisteminiam vėžio gydymui - Google Patents
Į egfr nukreipiamas dvigrandis rnr vektorius, skirtas sisteminiam vėžio gydymuiInfo
- Publication number
- LT3098239T LT3098239T LTEP16177258.7T LT16177258T LT3098239T LT 3098239 T LT3098239 T LT 3098239T LT 16177258 T LT16177258 T LT 16177258T LT 3098239 T LT3098239 T LT 3098239T
- Authority
- LT
- Lithuania
- Prior art keywords
- homing
- egfr
- double
- stranded rna
- cancer treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Information Transfer Between Computers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13969808P | 2008-12-22 | 2008-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3098239T true LT3098239T (lt) | 2020-02-10 |
Family
ID=42104511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP16177258.7T LT3098239T (lt) | 2008-12-22 | 2009-12-22 | Į egfr nukreipiamas dvigrandis rnr vektorius, skirtas sisteminiam vėžio gydymui |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9006406B2 (lt) |
| EP (3) | EP3098239B1 (lt) |
| JP (1) | JP2012513210A (lt) |
| CN (1) | CN102325794A (lt) |
| AU (1) | AU2009332522A1 (lt) |
| BR (1) | BRPI0922985A2 (lt) |
| CA (1) | CA2748125A1 (lt) |
| CY (1) | CY1123371T1 (lt) |
| DK (2) | DK3098239T3 (lt) |
| ES (2) | ES2602753T3 (lt) |
| HR (1) | HRP20192317T1 (lt) |
| HU (1) | HUE047759T2 (lt) |
| IL (1) | IL213739A0 (lt) |
| LT (1) | LT3098239T (lt) |
| MX (1) | MX2011006720A (lt) |
| PL (1) | PL3098239T3 (lt) |
| PT (1) | PT3098239T (lt) |
| SI (1) | SI3098239T1 (lt) |
| WO (1) | WO2010073247A2 (lt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6349304B2 (ja) | 2012-05-03 | 2018-06-27 | ヤンセン・サイエンシズ・アイルランド・ユーシー | 上気道感染症の処置のためのポリイノシン−ポリシチジル酸（ポリ（ｉ：ｃ））製剤 |
| JP6103832B2 (ja) | 2012-06-25 | 2017-03-29 | Hoya株式会社 | Ｅｇｆｒ結合性ペプチド |
| US9431064B2 (en) * | 2012-11-02 | 2016-08-30 | Taiwan Semiconductor Manufacturing Company, Ltd. | Memory circuit and cache circuit configuration |
| US10796320B2 (en) * | 2013-12-23 | 2020-10-06 | Mastercard International Incorporated | Systems and methods for passively determining a ratio of purchasers and prospective purchasers in a merchant location |
| WO2015173824A1 (en) * | 2014-05-14 | 2015-11-19 | Alex Levitzki Management And Holdings Ltd | Improved polyethyleneimine polyethyleneglycol vectors |
| EP3274840A4 (en) * | 2015-03-27 | 2018-12-26 | Intel Corporation | Dynamic cache allocation |
| CN112294757B (zh) * | 2015-11-17 | 2024-02-13 | 亮点医疗有限责任公司 | 包含含有双链聚核糖核苷酸与聚亚烷基亚胺的复合物的粒子的医药组合物 |
| GB201601868D0 (en) * | 2016-02-02 | 2016-03-16 | Lytix Biopharma As | Methods |
| CN105669964B (zh) * | 2016-03-04 | 2017-11-21 | 博瑞生物医药（苏州）股份有限公司 | 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用 |
| WO2018042411A1 (en) * | 2016-09-04 | 2018-03-08 | Alex Levitzki Management And Holdings, Ltd. | Chimeric proteins for targeting dsrna |
| CN115998757A (zh) * | 2017-05-17 | 2023-04-25 | 亮点医疗有限责任公司 | 包含具有双链多核糖核苷酸和聚乙烯亚胺的复合物的粒子的新型药物组合物 |
| IL273195B2 (en) * | 2017-09-27 | 2024-04-01 | Targimmune Therapeutics Ag | Castration-resistant prostate cancer |
| WO2020201568A1 (en) * | 2019-04-03 | 2020-10-08 | Targimmune Therapeutics Ag | Immunotherapy for the treatment of cancer |
| WO2020263770A1 (en) * | 2019-06-24 | 2020-12-30 | North Carolina State University | Nucleic acid compositions including a polyalkyleneimine-alkoxylene polymer and methods of making and using the same |
| WO2020263776A1 (en) * | 2019-06-24 | 2020-12-30 | North Carolina State University | Nucleic acid compositions including a polyalkyleneimine-alkoxylene polymer and methods of making and using the same |
| US10915418B1 (en) * | 2019-08-29 | 2021-02-09 | Snowflake Inc. | Automated query retry in a database environment |
| WO2024100044A1 (en) | 2022-11-07 | 2024-05-16 | Targimmune Therapeutics Ag | Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7927792B2 (en) | 2002-11-18 | 2011-04-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Targeted double stranded RNA mediated cell killing |
| WO2006054129A1 (en) * | 2004-11-19 | 2006-05-26 | Institut Gustave Roussy | Improved treatment of cancer by double-stranded rna |
| US7937291B2 (en) * | 2009-04-22 | 2011-05-03 | Visa U.S.A. Inc. | Providing an announcement about transactions of a target merchant to a consumer |
-
2009
- 2009-12-22 WO PCT/IL2009/001210 patent/WO2010073247A2/en active Application Filing
- 2009-12-22 HU HUE16177258A patent/HUE047759T2/hu unknown
- 2009-12-22 AU AU2009332522A patent/AU2009332522A1/en not_active Abandoned
- 2009-12-22 ES ES09806144.3T patent/ES2602753T3/es active Active
- 2009-12-22 JP JP2011542970A patent/JP2012513210A/ja not_active Withdrawn
- 2009-12-22 ES ES16177258T patent/ES2764396T3/es active Active
- 2009-12-22 BR BRPI0922985A patent/BRPI0922985A2/pt not_active IP Right Cessation
- 2009-12-22 EP EP16177258.7A patent/EP3098239B1/en active Active
- 2009-12-22 EP EP19204643.1A patent/EP3705493A1/en active Pending
- 2009-12-22 CN CN2009801572556A patent/CN102325794A/zh active Pending
- 2009-12-22 LT LTEP16177258.7T patent/LT3098239T/lt unknown
- 2009-12-22 US US13/141,345 patent/US9006406B2/en active Active
- 2009-12-22 DK DK16177258.7T patent/DK3098239T3/da active
- 2009-12-22 PL PL16177258T patent/PL3098239T3/pl unknown
- 2009-12-22 SI SI200932023T patent/SI3098239T1/sl unknown
- 2009-12-22 CA CA2748125A patent/CA2748125A1/en not_active Abandoned
- 2009-12-22 MX MX2011006720A patent/MX2011006720A/es not_active Application Discontinuation
- 2009-12-22 DK DK09806144.3T patent/DK2379597T3/en active
- 2009-12-22 EP EP09806144.3A patent/EP2379597B8/en active Active
- 2009-12-22 PT PT161772587T patent/PT3098239T/pt unknown
-
2011
- 2011-06-23 IL IL213739A patent/IL213739A0/en unknown
- 2011-09-22 US US13/239,784 patent/US20120330998A1/en not_active Abandoned
-
2019
- 2019-12-20 CY CY20191101340T patent/CY1123371T1/el unknown
- 2019-12-23 HR HRP20192317TT patent/HRP20192317T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2379597A2 (en) | 2011-10-26 |
| AU2009332522A1 (en) | 2011-08-11 |
| DK3098239T3 (da) | 2020-01-20 |
| PL3098239T3 (pl) | 2020-04-30 |
| JP2012513210A (ja) | 2012-06-14 |
| EP2379597B1 (en) | 2016-08-10 |
| SI3098239T1 (sl) | 2020-03-31 |
| ES2602753T3 (es) | 2017-02-22 |
| WO2010073247A2 (en) | 2010-07-01 |
| PT3098239T (pt) | 2020-01-15 |
| HRP20192317T1 (hr) | 2020-03-20 |
| CA2748125A1 (en) | 2010-07-01 |
| BRPI0922985A2 (pt) | 2016-10-04 |
| US20120330998A1 (en) | 2012-12-27 |
| IL213739A0 (en) | 2011-07-31 |
| MX2011006720A (es) | 2011-10-06 |
| WO2010073247A3 (en) | 2010-08-19 |
| CN102325794A (zh) | 2012-01-18 |
| DK2379597T3 (en) | 2016-12-05 |
| EP2379597B8 (en) | 2016-11-30 |
| EP3098239B1 (en) | 2019-10-23 |
| EP3098239A1 (en) | 2016-11-30 |
| EP3705493A1 (en) | 2020-09-09 |
| US9006406B2 (en) | 2015-04-14 |
| HUE047759T2 (hu) | 2020-05-28 |
| ES2764396T3 (es) | 2020-06-03 |
| US20120021006A1 (en) | 2012-01-26 |
| CY1123371T1 (el) | 2021-10-29 |
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