HUE047759T2 - EGFR vándorlást elõsegítõ, kettõs szálú RNS vektor rák szisztémás kezelésére - Google Patents

EGFR vándorlást elõsegítõ, kettõs szálú RNS vektor rák szisztémás kezelésére

Info

Publication number
HUE047759T2
HUE047759T2 HUE16177258A HUE16177258A HUE047759T2 HU E047759 T2 HUE047759 T2 HU E047759T2 HU E16177258 A HUE16177258 A HU E16177258A HU E16177258 A HUE16177258 A HU E16177258A HU E047759 T2 HUE047759 T2 HU E047759T2
Authority
HU
Hungary
Prior art keywords
homing
egfr
double
stranded rna
cancer treatment
Prior art date
Application number
HUE16177258A
Other languages
English (en)
Inventor
Alexander Levitzki
Alexei Shir
Original Assignee
Targimmune Therapeutics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targimmune Therapeutics Ag filed Critical Targimmune Therapeutics Ag
Publication of HUE047759T2 publication Critical patent/HUE047759T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/17Immunomodulatory nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Information Transfer Between Computers (AREA)
  • Peptides Or Proteins (AREA)
HUE16177258A 2008-12-22 2009-12-22 EGFR vándorlást elõsegítõ, kettõs szálú RNS vektor rák szisztémás kezelésére HUE047759T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13969808P 2008-12-22 2008-12-22

Publications (1)

Publication Number Publication Date
HUE047759T2 true HUE047759T2 (hu) 2020-05-28

Family

ID=42104511

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16177258A HUE047759T2 (hu) 2008-12-22 2009-12-22 EGFR vándorlást elõsegítõ, kettõs szálú RNS vektor rák szisztémás kezelésére

Country Status (19)

Country Link
US (2) US9006406B2 (hu)
EP (3) EP3705493A1 (hu)
JP (1) JP2012513210A (hu)
CN (1) CN102325794A (hu)
AU (1) AU2009332522A1 (hu)
BR (1) BRPI0922985A2 (hu)
CA (1) CA2748125A1 (hu)
CY (1) CY1123371T1 (hu)
DK (2) DK2379597T3 (hu)
ES (2) ES2602753T3 (hu)
HR (1) HRP20192317T1 (hu)
HU (1) HUE047759T2 (hu)
IL (1) IL213739A0 (hu)
LT (1) LT3098239T (hu)
MX (1) MX2011006720A (hu)
PL (1) PL3098239T3 (hu)
PT (1) PT3098239T (hu)
SI (1) SI3098239T1 (hu)
WO (1) WO2010073247A2 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201406208QA (en) 2012-05-03 2014-11-27 Janssen Sciences Ireland Uc Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections
JP6103832B2 (ja) 2012-06-25 2017-03-29 Hoya株式会社 Egfr結合性ペプチド
US9431064B2 (en) * 2012-11-02 2016-08-30 Taiwan Semiconductor Manufacturing Company, Ltd. Memory circuit and cache circuit configuration
US10796320B2 (en) * 2013-12-23 2020-10-06 Mastercard International Incorporated Systems and methods for passively determining a ratio of purchasers and prospective purchasers in a merchant location
KR102472590B1 (ko) * 2014-05-14 2022-11-30 타르그이뮨 테라퓨틱스 아게 개선된 폴리에틸렌이민 폴리에틸렌글리콜 벡터
CN107430556B (zh) * 2015-03-27 2021-07-20 英特尔公司 动态高速缓存分配
EP3639811B1 (en) * 2015-11-17 2024-03-20 Highlight Therapeutics, S.L. Novel pharmaceutical composition comprising particles comprising a complex of a double-stranded polyribonucleotide and a polyalkyleneimine
GB201601868D0 (en) * 2016-02-02 2016-03-16 Lytix Biopharma As Methods
CN105669964B (zh) * 2016-03-04 2017-11-21 博瑞生物医药(苏州)股份有限公司 卵巢癌特异靶向的生物可降解双亲性聚合物、由其制备的聚合物囊泡及应用
JP7096249B2 (ja) * 2016-09-04 2022-07-05 ターグイミューン セラピューティクス アーゲー dsRNAを標的化するためのキメラタンパク質
ES2924138T3 (es) * 2017-05-17 2022-10-04 Highlight Therapeutics S L Nueva composición farmacéutica que comprende partículas que comprenden un complejo de un polirribonucleótido de doble cadena y una polialquilenimina
AU2018342909B2 (en) * 2017-09-27 2023-06-08 Targimmune Therapeutics Ag Castration resistant prostate cancer
US20220175814A1 (en) * 2019-04-03 2022-06-09 Targimmune Therapeutics Ag Immunotherapy for the treatment of cancer
WO2020263770A1 (en) * 2019-06-24 2020-12-30 North Carolina State University Nucleic acid compositions including a polyalkyleneimine-alkoxylene polymer and methods of making and using the same
WO2020263776A1 (en) * 2019-06-24 2020-12-30 North Carolina State University Nucleic acid compositions including a polyalkyleneimine-alkoxylene polymer and methods of making and using the same
US10915418B1 (en) 2019-08-29 2021-02-09 Snowflake Inc. Automated query retry in a database environment
WO2024100044A1 (en) 2022-11-07 2024-05-16 Targimmune Therapeutics Ag Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006506433A (ja) 2002-11-18 2006-02-23 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム 標的化された二本鎖rna媒介による殺細胞
WO2006054129A1 (en) * 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
US7937291B2 (en) * 2009-04-22 2011-05-03 Visa U.S.A. Inc. Providing an announcement about transactions of a target merchant to a consumer

Also Published As

Publication number Publication date
CY1123371T1 (el) 2021-10-29
SI3098239T1 (sl) 2020-03-31
IL213739A0 (en) 2011-07-31
PT3098239T (pt) 2020-01-15
US9006406B2 (en) 2015-04-14
AU2009332522A1 (en) 2011-08-11
EP3098239B1 (en) 2019-10-23
WO2010073247A2 (en) 2010-07-01
HRP20192317T1 (hr) 2020-03-20
DK2379597T3 (en) 2016-12-05
US20120021006A1 (en) 2012-01-26
EP3705493A1 (en) 2020-09-09
EP2379597B1 (en) 2016-08-10
DK3098239T3 (da) 2020-01-20
MX2011006720A (es) 2011-10-06
EP2379597B8 (en) 2016-11-30
ES2602753T3 (es) 2017-02-22
WO2010073247A3 (en) 2010-08-19
EP3098239A1 (en) 2016-11-30
CN102325794A (zh) 2012-01-18
ES2764396T3 (es) 2020-06-03
BRPI0922985A2 (pt) 2016-10-04
PL3098239T3 (pl) 2020-04-30
LT3098239T (lt) 2020-02-10
EP2379597A2 (en) 2011-10-26
JP2012513210A (ja) 2012-06-14
CA2748125A1 (en) 2010-07-01
US20120330998A1 (en) 2012-12-27

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