LT2970361T - Kompozicijos ir būdai, skirti dauginei nukleorūgščių sintezei - Google Patents

Kompozicijos ir būdai, skirti dauginei nukleorūgščių sintezei

Info

Publication number
LT2970361T
LT2970361T LTEPPCT/US2014/026261T LT14026261T LT2970361T LT 2970361 T LT2970361 T LT 2970361T LT 14026261 T LT14026261 T LT 14026261T LT 2970361 T LT2970361 T LT 2970361T
Authority
LT
Lithuania
Prior art keywords
compositions
methods
nucleic acids
multiplex nucleic
acids synthesis
Prior art date
Application number
LTEPPCT/US2014/026261T
Other languages
English (en)
Inventor
Joseph Jacobson
Daniel Schindler
Ishtiaq SAAEM
Scott LAWTON
Martin J. Goldberg
Michael E. Hudson
Li-Yun A. KUNG
Original Assignee
Gen9, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen9, Inc. filed Critical Gen9, Inc.
Publication of LT2970361T publication Critical patent/LT2970361T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1031—Mutagenizing nucleic acids mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
LTEPPCT/US2014/026261T 2013-03-15 2014-03-13 Kompozicijos ir būdai, skirti dauginei nukleorūgščių sintezei LT2970361T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361792245P 2013-03-15 2013-03-15
PCT/US2014/026261 WO2014151696A1 (en) 2013-03-15 2014-03-13 Compositions and methods for multiplex nucleic acids synthesis

Publications (1)

Publication Number Publication Date
LT2970361T true LT2970361T (lt) 2023-05-10

Family

ID=51581014

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/US2014/026261T LT2970361T (lt) 2013-03-15 2014-03-13 Kompozicijos ir būdai, skirti dauginei nukleorūgščių sintezei

Country Status (8)

Country Link
US (3) US10273471B2 (lt)
EP (1) EP2970361B1 (lt)
CN (3) CN114525272A (lt)
AU (3) AU2014237003B2 (lt)
CA (1) CA2906556C (lt)
IL (3) IL292498A (lt)
LT (1) LT2970361T (lt)
WO (1) WO2014151696A1 (lt)

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EP4001427A1 (en) 2012-04-24 2022-05-25 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
LT2864531T (lt) 2012-06-25 2019-03-12 Gen9, Inc. Nukleorūgšties konstravimo ir aukšto produktyvumo sekvenavimo būdai
WO2014160059A1 (en) 2013-03-13 2014-10-02 Gen9, Inc. Compositions and methods for synthesis of high fidelity oligonucleotides
LT2970361T (lt) 2013-03-15 2023-05-10 Gen9, Inc. Kompozicijos ir būdai, skirti dauginei nukleorūgščių sintezei
JP6656733B2 (ja) 2013-08-05 2020-03-04 ツイスト バイオサイエンス コーポレーション 新規合成した遺伝子ライブラリ
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WO2016126987A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Compositions and methods for synthetic gene assembly
WO2016172377A1 (en) 2015-04-21 2016-10-27 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
US10844373B2 (en) 2015-09-18 2020-11-24 Twist Bioscience Corporation Oligonucleic acid variant libraries and synthesis thereof
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US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
CA3048182A1 (en) * 2015-12-21 2017-06-29 Gen9, Inc. Methods and compositions for nucleic acid assembly
JP2019522031A (ja) * 2016-07-28 2019-08-08 ギンゴー バイオワークス， インコーポレイテッド 核酸操作のための装置および方法
JP6854340B2 (ja) 2016-08-22 2021-04-07 ツイスト バイオサイエンス コーポレーション デノボ合成された核酸ライブラリ
KR102217487B1 (ko) 2016-09-21 2021-02-23 트위스트 바이오사이언스 코포레이션 핵산 기반 데이터 저장
US10538796B2 (en) * 2016-10-13 2020-01-21 Agilent Technologies, Inc. On-array ligation assembly
WO2018112426A1 (en) 2016-12-16 2018-06-21 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
WO2018156792A1 (en) 2017-02-22 2018-08-30 Twist Bioscience Corporation Nucleic acid based data storage
CN110913865A (zh) 2017-03-15 2020-03-24 特韦斯特生物科学公司 免疫突触的变体文库及其合成
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
EP3638782A4 (en) 2017-06-12 2021-03-17 Twist Bioscience Corporation SEALLESS NUCLEIC ACID ASSEMBLY METHODS
EA202090562A1 (ru) 2017-09-11 2020-08-10 Твист Байосайенс Корпорейшн Связывающие gpcr белки и их синтез
GB2566986A (en) 2017-09-29 2019-04-03 Evonetix Ltd Error detection during hybridisation of target double-stranded nucleic acid
KR20240024357A (ko) 2017-10-20 2024-02-23 트위스트 바이오사이언스 코포레이션 폴리뉴클레오타이드 합성을 위한 가열된 나노웰
KR20200106067A (ko) 2018-01-04 2020-09-10 트위스트 바이오사이언스 코포레이션 Dna 기반 디지털 정보 저장
AU2019270243A1 (en) 2018-05-18 2021-01-07 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
CA3131691A1 (en) 2019-02-26 2020-09-03 Twist Bioscience Corporation Variant nucleic acid libraries for antibody optimization
CN113766930A (zh) 2019-02-26 2021-12-07 特韦斯特生物科学公司 Glp1受体的变异核酸文库
GB201903056D0 (en) * 2019-03-07 2019-04-24 Nuclera Nucleics Ltd Method of oligonucleotide synthesis
CA3144644A1 (en) 2019-06-21 2020-12-24 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
CN114621307A (zh) * 2022-04-12 2022-06-14 中国科学院苏州生物医学工程技术研究所 一种寡核苷酸空间坐标编码方法及其微流控装置
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CA2817697C (en) * 2010-11-12 2021-11-16 Gen9, Inc. Methods and devices for nucleic acids synthesis
WO2012103154A1 (en) 2011-01-24 2012-08-02 Nugen Technologies, Inc. Stem-loop composite rna-dna adaptor-primers: compositions and methods for library generation, amplification and other downstream manipulations
ES2737957T3 (es) * 2011-08-26 2020-01-17 Gen9 Inc Composiciones y métodos para el ensamblaje de alta fidelidad de ácidos nucleicos
LT2970361T (lt) 2013-03-15 2023-05-10 Gen9, Inc. Kompozicijos ir būdai, skirti dauginei nukleorūgščių sintezei

Also Published As

Publication number Publication date
CN105209475B (zh) 2018-06-12
US20150376602A1 (en) 2015-12-31
AU2014237003A1 (en) 2015-09-03
AU2021240248A1 (en) 2021-10-28
US11130948B2 (en) 2021-09-28
CA2906556A1 (en) 2014-09-25
US20190203201A1 (en) 2019-07-04
IL271509A (en) 2020-02-27
CN108467863A (zh) 2018-08-31
US20210380968A1 (en) 2021-12-09
CA2906556C (en) 2022-07-05
US10273471B2 (en) 2019-04-30
EP2970361A1 (en) 2016-01-20
CN108467863B (zh) 2022-01-25
AU2019201052A1 (en) 2019-03-07
CN114525272A (zh) 2022-05-24
AU2019201052B2 (en) 2021-07-01
EP2970361A4 (en) 2016-11-23
WO2014151696A1 (en) 2014-09-25
IL292498A (en) 2022-06-01
AU2014237003B2 (en) 2018-11-15
IL240591B (en) 2019-02-28
EP2970361B1 (en) 2023-02-15
IL271509B (en) 2022-06-01
IL240591A0 (en) 2015-09-24
CN105209475A (zh) 2015-12-30

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