LT2601214T - Vegf antagonistų kompozicijos ir jų panaudojimas - Google Patents

Vegf antagonistų kompozicijos ir jų panaudojimas

Info

Publication number
LT2601214T
LT2601214T LTEP11745870.3T LT11745870T LT2601214T LT 2601214 T LT2601214 T LT 2601214T LT 11745870 T LT11745870 T LT 11745870T LT 2601214 T LT2601214 T LT 2601214T
Authority
LT
Lithuania
Prior art keywords
vegf antagonist
antagonist compositions
compositions
vegf
antagonist
Prior art date
Application number
LTEP11745870.3T
Other languages
English (en)
Inventor
James Stefano
Clark Pan
Huawei Qiu
Michael O`CALLAGHAN
Gloria Matthews
Original Assignee
Genzyme Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corporation filed Critical Genzyme Corporation
Publication of LT2601214T publication Critical patent/LT2601214T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/10Protein-tyrosine kinases (2.7.10)
    • C12Y207/10001Receptor protein-tyrosine kinase (2.7.10.1)
LTEP11745870.3T 2010-08-06 2011-08-05 Vegf antagonistų kompozicijos ir jų panaudojimas LT2601214T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37154610P 2010-08-06 2010-08-06
PCT/US2011/046802 WO2012019128A1 (en) 2010-08-06 2011-08-05 Vegf antagonist compositions and uses thereof

Publications (1)

Publication Number Publication Date
LT2601214T true LT2601214T (lt) 2018-02-26

Family

ID=44630479

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP11745870.3T LT2601214T (lt) 2010-08-06 2011-08-05 Vegf antagonistų kompozicijos ir jų panaudojimas

Country Status (12)

Country Link
US (2) US9441029B2 (lt)
EP (2) EP3327032A1 (lt)
CY (1) CY1121111T1 (lt)
DK (1) DK2601214T3 (lt)
ES (1) ES2652508T3 (lt)
HR (1) HRP20180154T1 (lt)
HU (1) HUE035554T2 (lt)
LT (1) LT2601214T (lt)
PL (1) PL2601214T3 (lt)
PT (1) PT2601214T (lt)
SI (1) SI2601214T1 (lt)
WO (1) WO2012019128A1 (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3377101A4 (en) * 2015-11-19 2019-08-07 Zhuhai Tairuishang Biopharm Ltd. VEGF BINDING METHODS AND COMPOSITIONS
AU2019212622A1 (en) 2018-01-26 2020-08-13 The Regents Of The University Of California Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents
IL293131A (en) 2019-11-25 2022-07-01 Univ California Long-acting vegf inhibitors for intraocular neovascularization

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US5567584A (en) 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
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BR9207175A (pt) 1992-10-28 1995-12-12 Genentech Inc Composição contendo antagonista de fator de crescimento de célula endotelial vascular sequência aminoácida de anticorpo monoclonal polipeptídeo e método de tratamento de tumor em mamífero
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CA2158745C (en) 1993-03-25 2007-06-19 Richard L. Kendall Inhibitor of vascular endothelial cell growth factor
US6686200B1 (en) 1993-08-31 2004-02-03 Uab Research Foundation Methods and compositions for the large scale production of recombinant adeno-associated virus
US5827702A (en) 1994-10-31 1998-10-27 Genentech, Inc. Ocular gene therapy
JPH09154588A (ja) 1995-10-07 1997-06-17 Toagosei Co Ltd Vegf結合性ポリペプチド
US6100071A (en) 1996-05-07 2000-08-08 Genentech, Inc. Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
DE69736860T2 (de) 1996-09-24 2007-05-16 Merck & Co., Inc. Verbindungen zur hemmung der angiogenese durch gentherapie
WO1998031794A1 (fr) 1997-01-17 1998-07-23 Toa Gosei Co., Ltd. Polypeptide liant le facteur vegf
AU7383298A (en) 1997-05-13 1998-12-08 Regents Of The University Of California, The Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
ATE312935T1 (de) 1997-06-03 2005-12-15 Regulatorische sequenzen für die in-vivo- expression einer heterologen dns-sequenz in endothelzellen und ihre verwendungen.
ATE371727T1 (de) 1997-06-18 2007-09-15 Merck & Co Inc Kdr, ein menschlicher tyrosin kinase rezeptor
AU9319198A (en) 1997-09-19 1999-04-05 Trustees Of The University Of Pennsylvania, The Methods and vector constructs useful for production of recombinant aav
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US6943153B1 (en) 1999-03-15 2005-09-13 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
AU3755900A (en) 1999-03-15 2000-10-04 Chiron Corporation Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
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US6821775B1 (en) 2000-02-11 2004-11-23 Genvec, Inc. Viral vector encoding pigment epithelium-derived factor
WO2002024234A2 (en) 2000-09-20 2002-03-28 The Regents Of The University Of California Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
CZ20031927A3 (cs) 2001-01-09 2003-10-15 Merck Patent Gmbh Farmaceutický prostředek na bázi inhibitorů receptoru tyrosinkinázy a inhibitorů angiogeneze
US20060193830A1 (en) 2002-03-20 2006-08-31 Hauswirth William W Raav vector compositions and methods for the treatment of choroidal neovascularization
CU23178A1 (es) 2002-04-15 2006-09-22 Ct Ingenieria Genetica Biotech INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA
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EP1804835B9 (en) * 2004-09-13 2012-05-02 Genzyme Corporation Multimeric constructs
NZ555286A (en) 2004-12-17 2010-04-30 Genentech Inc Antiangiogenesis therapy of autoimmune disease in patients who have failed prior therapy
WO2010019263A2 (en) * 2008-08-15 2010-02-18 Genzyme Corporation Soluble flt constructs for treating cancers

Also Published As

Publication number Publication date
US10308917B2 (en) 2019-06-04
WO2012019128A1 (en) 2012-02-09
EP3327032A1 (en) 2018-05-30
PT2601214T (pt) 2017-12-20
DK2601214T3 (en) 2018-02-05
US20130324465A1 (en) 2013-12-05
HRP20180154T1 (hr) 2018-03-09
SI2601214T1 (en) 2018-03-30
ES2652508T3 (es) 2018-02-02
US20160326501A1 (en) 2016-11-10
EP2601214B1 (en) 2017-11-01
PL2601214T3 (pl) 2018-05-30
CY1121111T1 (el) 2019-12-11
EP2601214A1 (en) 2013-06-12
US9441029B2 (en) 2016-09-13
HUE035554T2 (en) 2018-05-02

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