LT2398488T - Depo sistema, apimanti glatiramero acetatą - Google Patents

Depo sistema, apimanti glatiramero acetatą

Info

Publication number
LT2398488T
LT2398488T LTEP10840699.2T LT10840699T LT2398488T LT 2398488 T LT2398488 T LT 2398488T LT 10840699 T LT10840699 T LT 10840699T LT 2398488 T LT2398488 T LT 2398488T
Authority
LT
Lithuania
Prior art keywords
glatiramer acetate
depot system
depot
glatiramer
acetate
Prior art date
Application number
LTEP10840699.2T
Other languages
English (en)
Inventor
Ehud Marom
Shai Rubnov
Original Assignee
Mapi Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mapi Pharma Limited filed Critical Mapi Pharma Limited
Publication of LT2398488T publication Critical patent/LT2398488T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
LTEP10840699.2T 2010-01-04 2010-08-19 Depo sistema, apimanti glatiramero acetatą LT2398488T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29192810P 2010-01-04 2010-01-04
PCT/IL2010/000679 WO2011080733A1 (en) 2010-01-04 2010-08-19 Depot systems comprising glatiramer or a pharmacologically acceptable salt thereof

Publications (1)

Publication Number Publication Date
LT2398488T true LT2398488T (lt) 2019-01-25

Family

ID=44226217

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP10840699.2T LT2398488T (lt) 2010-01-04 2010-08-19 Depo sistema, apimanti glatiramero acetatą
LTEP18205308.2T LT3536333T (lt) 2010-01-04 2010-08-19 Depo sistema, apimanti glatiramero acetatą

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP18205308.2T LT3536333T (lt) 2010-01-04 2010-08-19 Depo sistema, apimanti glatiramero acetatą

Country Status (20)

Country Link
US (1) US8796226B2 (lt)
EP (2) EP2398488B1 (lt)
JP (2) JP5916622B2 (lt)
CN (3) CN107661490B (lt)
AU (1) AU2010337822B2 (lt)
BR (1) BR112012016459B1 (lt)
CA (1) CA2784394C (lt)
CY (1) CY1120975T1 (lt)
DK (2) DK3536333T3 (lt)
ES (2) ES2699692T3 (lt)
HK (2) HK1245667A1 (lt)
HR (2) HRP20221208T1 (lt)
HU (2) HUE040390T2 (lt)
LT (2) LT2398488T (lt)
MX (2) MX2020003805A (lt)
PL (2) PL2398488T3 (lt)
PT (2) PT2398488T (lt)
SI (1) SI2398488T1 (lt)
TR (1) TR201818858T4 (lt)
WO (1) WO2011080733A1 (lt)

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US8377885B2 (en) 2010-01-04 2013-02-19 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
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WO2013038399A1 (en) 2011-09-18 2013-03-21 Bio Plasmar Ltd Bio-degradable compositions and use thereof
WO2014128079A1 (en) * 2013-02-19 2014-08-28 Synthon B.V. Glatiramer acetate multidose formulation
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US10493122B2 (en) 2014-03-17 2019-12-03 Mapi Pharma Ltd. Sublingual delivery of glatiramer acetate
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WO2018002930A1 (en) * 2016-06-30 2018-01-04 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
MX2019001999A (es) * 2016-08-28 2019-08-29 Mapi Pharma Ltd Proceso para la preparacion de microparticulas que contienen acetato de glatiramer.
HRP20230738T1 (hr) 2016-08-31 2023-10-27 Mapi Pharma Ltd Depo sustavi koji sadrže glatiramer acetat
AU2016428204B2 (en) * 2016-10-28 2019-09-26 SpineThera Pharmaceutical compositions and uses thereof
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WO2018178973A1 (en) * 2017-03-26 2018-10-04 Mapi Pharma Ltd. Glatiramer depot systems for treating progressive forms of multiple sclerosis
JP2020519645A (ja) 2017-05-15 2020-07-02 ステム セル メディスン リミテッド 脂肪組織由来幹細胞による多発性硬化症の治療
JP7000458B2 (ja) * 2017-05-15 2022-02-10 ステム セル メディスン リミテッド 長時間作用性グラチラマー及び脂肪由来幹細胞での多発性硬化症の治療
US10323289B2 (en) 2017-06-26 2019-06-18 Institut Pasteur Treatments to eliminate HIV reservoirs and reduce viral load
WO2022003662A1 (en) * 2020-06-29 2022-01-06 Mapi Pharma Ltd. Low burst-release liraglutide depot systems
EP4236990A1 (en) * 2020-11-02 2023-09-06 Simcha Il-18, Inc. Interleukin-18 variants and methods of use
EP4277661A1 (en) 2021-01-18 2023-11-22 Anton Frenkel Pharmaceutical dosage form
JP2024507598A (ja) * 2021-01-29 2024-02-21 ティオンラボ・セラピューティクス 初期放出制御されたデポー組成物及びその製造方法
US11865213B2 (en) 2021-07-05 2024-01-09 Mapi Pharma Ltd. Semaglutide depot systems and use thereof
WO2023281406A1 (en) 2021-07-06 2023-01-12 Mark Hasleton Treatment of serotonin reuptake inhibitor withdrawal syndrome
WO2023170493A1 (en) * 2022-03-07 2023-09-14 Hadidi Naghmeh Drug delivery using a parenteral pharmaceutical composition
WO2024054879A1 (en) * 2022-09-06 2024-03-14 Regents Of The University Of Michigan Biodegradable polymeric particles for delivery of positively charged therapeutic agents

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Also Published As

Publication number Publication date
LT3536333T (lt) 2022-11-10
HUE040390T2 (hu) 2019-03-28
AU2010337822B2 (en) 2016-03-17
PL2398488T3 (pl) 2019-03-29
EP2398488A1 (en) 2011-12-28
CA2784394A1 (en) 2011-07-07
CA2784394C (en) 2016-12-13
JP2013516403A (ja) 2013-05-13
CN107184954A (zh) 2017-09-22
PT3536333T (pt) 2022-11-11
JP5916622B2 (ja) 2016-05-11
PT2398488T (pt) 2018-12-20
US20120015891A1 (en) 2012-01-19
BR112012016459A2 (pt) 2017-10-03
HUE060304T2 (hu) 2023-02-28
DK2398488T3 (en) 2019-01-28
WO2011080733A1 (en) 2011-07-07
JP2016074696A (ja) 2016-05-12
EP2398488B1 (en) 2018-11-14
SI2398488T1 (sl) 2019-02-28
AU2010337822A1 (en) 2012-07-12
MX2020003805A (es) 2022-05-05
CY1120975T1 (el) 2019-12-11
CN107661490A (zh) 2018-02-06
CN107661490B (zh) 2021-12-31
MX349162B (es) 2017-07-14
DK3536333T3 (da) 2022-10-24
TR201818858T4 (tr) 2019-01-21
HK1245667A1 (zh) 2018-08-31
EP2398488A4 (en) 2014-06-11
ES2928900T3 (es) 2022-11-23
ES2699692T3 (es) 2019-02-12
EP3536333A1 (en) 2019-09-11
PL3536333T3 (pl) 2022-12-05
US8796226B2 (en) 2014-08-05
CN102686235A (zh) 2012-09-19
BR112012016459B1 (pt) 2020-01-14
HRP20221208T1 (hr) 2022-12-09
HK1244430A1 (zh) 2018-08-10
EP3536333B1 (en) 2022-08-03
HRP20182076T1 (hr) 2019-02-08
MX2012007760A (es) 2012-08-01

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