KR970009813A - 트라마돌 또는 트라마돌 염의 신속하게 붕해되는 의약 형태 - Google Patents

트라마돌 또는 트라마돌 염의 신속하게 붕해되는 의약 형태 Download PDF

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Publication number
KR970009813A
KR970009813A KR1019960034101A KR19960034101A KR970009813A KR 970009813 A KR970009813 A KR 970009813A KR 1019960034101 A KR1019960034101 A KR 1019960034101A KR 19960034101 A KR19960034101 A KR 19960034101A KR 970009813 A KR970009813 A KR 970009813A
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KR
South Korea
Prior art keywords
tramadol
salt
rapid disintegration
tablet
tablet according
Prior art date
Application number
KR1019960034101A
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English (en)
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KR100642966B1 (ko
Inventor
김미경
하루오 요시이
미쯔루 나이키
유리꼬 후카타
위르겐 베칭
요한네스 하인리히 안토니우스 바르톨로메우스
Original Assignee
김미경
코니시 진우에몬
닛폰조키세야쿠 카부시키가이샤
비르츠 프란츠, 파우쓰-베르구스
그뤼넨탈 게엠베하
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Publication date
Priority claimed from JP7227045A external-priority patent/JPH0959180A/ja
Priority claimed from DE19530575A external-priority patent/DE19530575A1/de
Application filed by 김미경, 코니시 진우에몬, 닛폰조키세야쿠 카부시키가이샤, 비르츠 프란츠, 파우쓰-베르구스, 그뤼넨탈 게엠베하 filed Critical 김미경
Publication of KR970009813A publication Critical patent/KR970009813A/ko
Application granted granted Critical
Publication of KR100642966B1 publication Critical patent/KR100642966B1/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

본 발명은 경구 투여용의 트라마돌 또는 트라마돌 염의 결합제 비함유 정제에 관한 것이다.

Description

트라마돌 또는 트라마돌 염의 신속하게 붕해되는 의약 형태
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 미세결정성 셀룰로즈와 트라마돌 또는 트라마돌 염을 2:1 이상의 중량비로 포함하는, 경구투여용의 트라마돌 또는 트라마돌 염의 결합제-비함유 정제.
  2. 제 1항에 있어서, 미세결정성 셀룰로즈 대 트라마돌 또는 트라마돌 염의 중량비가 3:1 이상, 바람직하게는 4:1 이상임을 특징으로 하는 정제.
  3. 제 1항 또는 제 2항에 있어서, 전분을 포함하는 것을 특징으로 하는 정제.
  4. 제 3항에 있어서, 전분 대 트라마돌 또는 트라마돌 염의 중량비가 1:1임을 특징으로 하는 정제.
  5. 제 1항 내지 제 4항 중 어느 한 항에 있어서, 임의 성분으로서 하나 이상의 붕해제를 0.5 내지 10중량% 포함함을 특징으로 하는 정제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960034101A 1995-08-11 1996-08-17 트라마돌 하이드로클로라이드를 함유하는 정제 KR100642966B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP7227045A JPH0959180A (ja) 1995-08-11 1995-08-11 活性化免疫グロブリン
JP95-227045 1995-08-11
DE19530575A DE19530575A1 (de) 1995-08-19 1995-08-19 Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
DE19530575.2 1995-08-19

Publications (2)

Publication Number Publication Date
KR970009813A true KR970009813A (ko) 1997-03-27
KR100642966B1 KR100642966B1 (ko) 2006-12-22

Family

ID=66251549

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960034101A KR100642966B1 (ko) 1995-08-11 1996-08-17 트라마돌 하이드로클로라이드를 함유하는 정제

Country Status (1)

Country Link
KR (1) KR100642966B1 (ko)

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Publication number Publication date
KR100642966B1 (ko) 2006-12-22

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