KR960700772A - 액체 및 멸균된 의학적 물질의 저장 및 전달을 위한 선행충진 주사기 (prefilled syringe for storing and dispensing a sterile liquid drug) - Google Patents

액체 및 멸균된 의학적 물질의 저장 및 전달을 위한 선행충진 주사기 (prefilled syringe for storing and dispensing a sterile liquid drug) Download PDF

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Publication number
KR960700772A
KR960700772A KR1019950703519A KR19950703519A KR960700772A KR 960700772 A KR960700772 A KR 960700772A KR 1019950703519 A KR1019950703519 A KR 1019950703519A KR 19950703519 A KR19950703519 A KR 19950703519A KR 960700772 A KR960700772 A KR 960700772A
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South Korea
Prior art keywords
syringe
shoulder
piston
valve
shaft
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KR1019950703519A
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English (en)
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메이어 가브리엘
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토마스 스테인먼
메디코프 호울딩스 에스. 에이.
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Publication of KR960700772A publication Critical patent/KR960700772A/ko

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2429Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1443Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/322Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
    • A61M5/502Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3103Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106Plugs for syringes without needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M2005/3131Syringe barrels specially adapted for improving sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M39/26Valves closing automatically on disconnecting the line and opening on reconnection thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2459Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3145Filters incorporated in syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental & Geological Engineering (AREA)
  • Ophthalmology & Optometry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Materials For Medical Uses (AREA)

Abstract

본 발명은 액체 및 면균된 의학적 물질의 저장 및 전달을 위해 유리로 만들어지고 폐쇄단 바닥 및 반대의 열린 끝에는 저장기의 반대로 축으로 미끄러질 수 있는 마개-피스톤-밸브에 의해 폐쇄된 견고한 저장층을 갖고 있는 선행 충진 주사기에 관한것이다. 그 저장기는 원통 몸체내에서 축으로 움직일수 있고 마개-피스톤-밸브에 연결된 자루를 갖고 있고 몸체의 끝에 고정된 바늘과 연결하도록 개작된 축관이 제공된다.

Description

액체 및 멸균된 의학적 물질의 저장 및 전달을 위한 선행충진 주사기 (PREFILLED SYRINGE FOR STORING AND DISPENSING A STERILE LIQUID DRUG)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 저장 위치가 보이는 본 발명에 있어서의 선행 충진 주사기의 단면도를 보여준다.

Claims (8)

  1. 액체와 멸균의 약물질의 보관 및 전달용 예비충전 주사기로서, 유리로 제조되고 바닥이 폐쇄되어 있으며 바닥의 반대편 단부의 축방향으로 슬라이딩이 가능한 스토피-피스톤-밸브로 막혀 있는 견고한 장약실을 구비하고 있고, 스토피-피스톤-밸브(17)에 연결된 샤프트(22)를 구비하고 있으며, 장약사이 원통체의 단부에 고정된 바늘에 연통되도록 되어 있는 축방향도관(23)이 제공되어 있는 주사기에 있어서, 스토퍼-피스톤-밸브(17)에는 2개의 밀접하게 고정된 립들로 한정된 슬롯(19) 형태의 개구부를 구비한 중심 영역이 설치되어 있고, 샤프트에는 장약실(11)이 원통형채(13)내에 축방향으로 배치되었을 때 스토퍼-피스톤-밸브(17)에 견고하게 연결된 수단들이 제공되어 잇으며, 축방향 도관(23)에는 립을 분리시키고 슬롯(19)을 개방시켜 축방향 도관(23)을 장약실(11)과 연통시키도록 자체의 축방향에 대하여 실질적으로 수직면을 따라 절단단부가 제공되어 있는 것을 특징으로 하는 주사기.
  2. 제1항에 잇어서, 샤프트(22)가 원통형체의 원위 단부를 지지하는 플랜지(24)에 연결된 것을 특징으로 하는 주사기.
  3. 제1항에 있어서, 사프트를 연결하는 수단에는 주변에 네크(35)가 설치된 클램핑 블록이 포함되고 이것은 네크의 양쪽에 제1 및 제2쇼울더(36,37)가 제공되어 있고, 스토퍼-피스톤-밸브의 중심영역에는 환형돌출부(38)가 제공되어 있으며, 상기 돌출부는 주사기의 보관 중에, 네트내에서 샤프트와 스토포-피스톤-밸브가 서로간의 항균 격벽으로서 형성된 기밀상태를 유지할 수 있도록 되어 있는 것을 특징으로 하는 주사기.
  4. 제3항에 있어서, 제1쇼울더는 제2쇼울더(37)보다 돌출부의 압력에 대한 내성을 덜 제공하도록 되어 있는 것을 특징으로 하는 주사기.
  5. 제4항에 있어서, 제1쇼울더(36)는 제2쇼울더(37)보다 치수가 더 작은 것을 특징으로 하는 주사기.
  6. 제1항에 있어서, 스토퍼-피스톤-밸브(17)에는 보관 중에 장약실이 내부 쇼울더(61)에 대한 지지를 할 수 있도록 1개 이상의 쇼울더(60)를 구비하고 있는 것을 특징으로 하는 주사기.
  7. 제1항에 있어서, 장약실(11)은 본체(13)의 자유단부에 제공된 네크(31)과 협동할 수 있는 외측 쇼울더(30)가 구비된 것을 특징으로 하는 주사기.
  8. 제1항에 있어서, 장약실(11)은 사용후에 샤프트(22)의 베이스부에 위치한 확대부(33)과 협동할 수 있게 된 내측 쇼울더(32)를 구비하고 있는 것을 특징으로 하는 주사기.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950703519A 1993-02-19 1994-02-18 액체 및 멸균된 의학적 물질의 저장 및 전달을 위한 선행충진 주사기 (prefilled syringe for storing and dispensing a sterile liquid drug) KR960700772A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR93/01998 1993-02-19
FR9301998 1993-02-19
PCT/IB1994/000016 WO1994019034A1 (fr) 1993-02-19 1994-02-18 Seringue preremplie de stockage et de transfert d'une substance medicamenteuse liquide et sterile

Publications (1)

Publication Number Publication Date
KR960700772A true KR960700772A (ko) 1996-02-24

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KR1019950703519A KR960700772A (ko) 1993-02-19 1994-02-18 액체 및 멸균된 의학적 물질의 저장 및 전달을 위한 선행충진 주사기 (prefilled syringe for storing and dispensing a sterile liquid drug)

Country Status (19)

Country Link
US (1) US5478324A (ko)
EP (1) EP0684846B1 (ko)
JP (1) JPH08506749A (ko)
KR (1) KR960700772A (ko)
CN (1) CN1118145A (ko)
AT (1) ATE179621T1 (ko)
AU (1) AU678573B2 (ko)
BR (1) BR9406249A (ko)
CA (1) CA2156492A1 (ko)
CZ (1) CZ284900B6 (ko)
DE (1) DE69418314T2 (ko)
ES (1) ES2133535T3 (ko)
FI (1) FI953879A (ko)
HU (1) HU215634B (ko)
NO (1) NO953214D0 (ko)
NZ (1) NZ287126A (ko)
PL (1) PL310319A1 (ko)
SK (1) SK102695A3 (ko)
WO (1) WO1994019034A1 (ko)

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CA2460063C (en) * 2001-09-12 2010-07-20 Becton, Dickinson And Company Microneedle-based pen device for drug delivery and method for using same
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HU215634B (hu) 1999-01-28
CA2156492A1 (fr) 1994-09-01
NO953214L (no) 1995-08-16
CZ212695A3 (en) 1995-12-13
SK102695A3 (en) 1995-12-06
US5478324A (en) 1995-12-26
HU9502418D0 (en) 1995-10-30
EP0684846B1 (fr) 1999-05-06
WO1994019034A1 (fr) 1994-09-01
FI953879A0 (fi) 1995-08-17
PL310319A1 (en) 1995-12-11
FI953879A (fi) 1995-08-17
AU6253894A (en) 1994-09-14
NZ287126A (en) 1997-10-24
CN1118145A (zh) 1996-03-06
CZ284900B6 (cs) 1999-04-14
DE69418314D1 (de) 1999-06-10
EP0684846A1 (fr) 1995-12-06
ES2133535T3 (es) 1999-09-16
ATE179621T1 (de) 1999-05-15
JPH08506749A (ja) 1996-07-23
HUT73504A (en) 1996-08-28
NO953214D0 (no) 1995-08-16
DE69418314T2 (de) 1999-12-16
BR9406249A (pt) 1996-01-02

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