KR950702121A - 포스포네이트 및 비스테로이드계 소염 약물(nasid)을 함유하는 관절염 치료 조성물(compositions for the treatment of arthritis containing phosphonates and nsaids) - Google Patents
포스포네이트 및 비스테로이드계 소염 약물(nasid)을 함유하는 관절염 치료 조성물(compositions for the treatment of arthritis containing phosphonates and nsaids)Info
- Publication number
- KR950702121A KR950702121A KR1019940704867A KR19940704867A KR950702121A KR 950702121 A KR950702121 A KR 950702121A KR 1019940704867 A KR1019940704867 A KR 1019940704867A KR 19940704867 A KR19940704867 A KR 19940704867A KR 950702121 A KR950702121 A KR 950702121A
- Authority
- KR
- South Korea
- Prior art keywords
- phosphonate
- administered
- day
- nsaid
- administration
- Prior art date
Links
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 title abstract 6
- 206010003246 arthritis Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 5
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 abstract 5
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 230000009885 systemic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90672692A | 1992-06-30 | 1992-06-30 | |
| PCT/US1993/005627 WO1994000130A1 (en) | 1992-06-30 | 1993-06-14 | Compositions for the treatment of arthritis containing phosphonates and nsaids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR950702121A true KR950702121A (ko) | 1995-06-19 |
Family
ID=25422881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019940704867A KR950702121A (ko) | 1992-06-30 | 1994-12-30 | 포스포네이트 및 비스테로이드계 소염 약물(nasid)을 함유하는 관절염 치료 조성물(compositions for the treatment of arthritis containing phosphonates and nsaids) |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5869471A (ko) |
| EP (1) | EP0650361B1 (ko) |
| JP (1) | JPH07508279A (ko) |
| KR (1) | KR950702121A (ko) |
| AT (1) | ATE179329T1 (ko) |
| AU (1) | AU675796B2 (ko) |
| CA (1) | CA2138366C (ko) |
| DE (1) | DE69324684T2 (ko) |
| DK (1) | DK0650361T3 (ko) |
| ES (1) | ES2133402T3 (ko) |
| GR (1) | GR3030076T3 (ko) |
| HU (1) | HUT72437A (ko) |
| MA (1) | MA22914A1 (ko) |
| MX (1) | MX9303969A (ko) |
| NZ (1) | NZ253631A (ko) |
| RU (1) | RU2119794C1 (ko) |
| SK (1) | SK160994A3 (ko) |
| WO (1) | WO1994000130A1 (ko) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994329A (en) | 1997-07-22 | 1999-11-30 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| US6432932B1 (en) | 1997-07-22 | 2002-08-13 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| WO2001076577A2 (en) * | 2000-04-07 | 2001-10-18 | The Board Of Regents Of The University Of Texas System | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced gi toxicity |
| EP1284729A4 (en) * | 2000-04-13 | 2007-12-19 | Mayo Foundation | REDUCTION AGENTS OF A (BETA) 42 |
| CA2347330C (en) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
| CA2469779C (en) * | 2001-12-21 | 2008-02-12 | The Procter & Gamble Company | Method for the treatment of bone disorders |
| US20050070504A1 (en) * | 2001-12-21 | 2005-03-31 | The Procter & Gamble Co. | Risedronate compositions and their methods of use |
| CA2501381A1 (en) * | 2002-10-15 | 2004-04-29 | Novartis Ag | Method of administering bisphosphonates |
| EP1603548A4 (en) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS |
| EP1651195A4 (en) * | 2003-07-11 | 2007-10-03 | Myriad Genetics Inc | PHARMACEUTICAL PROCESSES, DOSIERSCHEMATA AND DOSAGE FORMS FOR THE TREATMENT OF ALZHEIMER DISEASE |
| US20070293538A1 (en) * | 2004-04-13 | 2007-12-20 | Myriad Genetics, Incorporated | Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders |
| EP1745180A1 (en) * | 2004-04-29 | 2007-01-24 | Keystone Retaining Wall Systems, Inc. | Veneers for walls, retaining walls and the like |
| AU2005240107A1 (en) * | 2004-05-06 | 2005-11-17 | Merck & Co., Inc. | Methods for treating arthritic conditions in dogs |
| WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| CA2618985A1 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| BRPI0613611A2 (pt) * | 2005-07-22 | 2011-01-18 | Myriad Genetics Inc | formulações de alta concentração de fármaco e formas de dosagens |
| MY149159A (en) * | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| MX2008009992A (es) * | 2006-02-06 | 2008-10-17 | Cypress Bioscience Inc | Composiciones que contienen bisfosfonato y un antifolato. |
| KR20080111070A (ko) * | 2006-03-17 | 2008-12-22 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 비스포스포네이트 화합물 및 방법 |
| EP2046119A2 (en) * | 2006-07-07 | 2009-04-15 | Myriad Genetics, Inc. | Treatment of psychiatric disorders |
| US20090012165A1 (en) * | 2007-07-03 | 2009-01-08 | Sucampo Ag | Pharmaceutical combination of nsaid and prostaglandin compound |
| DK2543357T3 (en) | 2011-07-07 | 2018-07-02 | Holy Stone Healthcare Co Ltd | COMPOSITION FOR USE FOR TREATMENT AND PREVENTION OF INFLAMMATION-RELATED DISORDERS |
| US9827192B2 (en) | 2012-05-14 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10350227B2 (en) | 2012-05-14 | 2019-07-16 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10092581B2 (en) | 2014-05-15 | 2018-10-09 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US10111837B2 (en) | 2012-05-14 | 2018-10-30 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds |
| US9669040B2 (en) | 2012-05-14 | 2017-06-06 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9770457B2 (en) | 2012-05-14 | 2017-09-26 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesion |
| US9662343B2 (en) | 2012-05-14 | 2017-05-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10493085B2 (en) | 2012-05-14 | 2019-12-03 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US9655908B2 (en) | 2012-05-14 | 2017-05-23 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
| US9427403B2 (en) | 2012-05-14 | 2016-08-30 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US10413561B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases |
| US10028908B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9901589B2 (en) | 2012-05-14 | 2018-02-27 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9289441B2 (en) | 2014-08-08 | 2016-03-22 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US8865757B1 (en) | 2014-05-28 | 2014-10-21 | Antecip Bioventures Ii Llp | Therapeutic compositions comprising imidazole and imidazolium compounds |
| US9694023B2 (en) | 2012-05-14 | 2017-07-04 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US9861648B2 (en) | 2012-05-14 | 2018-01-09 | Antecip Boiventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US9999629B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9789128B2 (en) | 2012-05-14 | 2017-10-17 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10016446B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating Paget's disease of bone |
| US9211257B2 (en) | 2012-05-14 | 2015-12-15 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US9844559B2 (en) | 2012-05-14 | 2017-12-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating bone marrow lesions |
| US10413560B2 (en) | 2012-05-14 | 2019-09-17 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
| US10463682B2 (en) | 2012-05-14 | 2019-11-05 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating low back pain |
| US9956237B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US11654152B2 (en) | 2012-05-14 | 2023-05-23 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
| US9707247B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9949993B2 (en) | 2012-05-14 | 2018-04-24 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9895383B2 (en) | 2012-05-14 | 2018-02-20 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US8802658B2 (en) | 2012-05-14 | 2014-08-12 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating disease |
| US9782421B1 (en) | 2012-05-14 | 2017-10-10 | Antecip Bioventures Ii Llc | Neridronic acid molecular complex for treating complex regional pain syndrome |
| US9956234B2 (en) | 2012-05-14 | 2018-05-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
| US10039773B2 (en) | 2012-05-14 | 2018-08-07 | Antecip Bioventures Ii Llc | Neridronic acid for treating arthritis |
| US9820999B2 (en) | 2012-05-14 | 2017-11-21 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9877977B2 (en) | 2012-05-14 | 2018-01-30 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10080765B2 (en) | 2012-05-14 | 2018-09-25 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US10173986B2 (en) | 2012-05-14 | 2019-01-08 | Antecip Bioventures Ii Llc | Methods for the safe administration of imidazole or imidazolium compounds |
| US10004756B2 (en) | 2014-05-15 | 2018-06-26 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9707245B2 (en) | 2012-05-14 | 2017-07-18 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9925203B2 (en) | 2012-05-14 | 2018-03-27 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US10028969B2 (en) | 2012-05-14 | 2018-07-24 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9943531B2 (en) | 2014-08-08 | 2018-04-17 | Antecip Bioventures Ii Llc | Osteoclast inhibitors such as zoledronic acid for low back pain treatment |
| US10016445B2 (en) | 2012-05-14 | 2018-07-10 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9700570B2 (en) | 2014-05-27 | 2017-07-11 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US10034890B2 (en) | 2012-05-14 | 2018-07-31 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9867840B2 (en) | 2014-05-27 | 2018-01-16 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9717747B2 (en) | 2012-05-14 | 2017-08-01 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for knee conditions |
| US9795622B2 (en) | 2012-05-14 | 2017-10-24 | Antecip Bioventures Ii Llc | Neridronic acid for treating pain associated with a joint |
| US9956238B2 (en) | 2014-05-15 | 2018-05-01 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating low back pain |
| US9867839B2 (en) | 2012-05-14 | 2018-01-16 | Antecip Bioventures Ii Llc | Osteoclast inhibitors for joint conditions |
| US9999628B2 (en) | 2012-05-14 | 2018-06-19 | Antecip Bioventures Ii Llc | Neridronic acid for treating complex regional pain syndrome |
| US9616078B2 (en) | 2012-05-14 | 2017-04-11 | Antecip Bioventures Ii Llc | Dosage forms for oral administration of zoledronic acid or related compounds for treating disease |
| US9675626B2 (en) | 2012-05-14 | 2017-06-13 | Antecip Bioventures Ii Llc | Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome |
| US9827256B2 (en) | 2014-05-27 | 2017-11-28 | Antecip Bioventures Ii Llc | Compositions for administration of zoledronic acid or related compounds for treating lower back pain |
| US9127069B1 (en) | 2014-06-11 | 2015-09-08 | Antecip Bioventures LLC | Compositions comprising rank/rankl antagonists and related compounds for treating pain |
| WO2016127035A1 (en) * | 2015-02-05 | 2016-08-11 | Duke University | Methods of detecting osteoarthritis and predicting progression thereof |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3676554A (en) * | 1970-10-30 | 1972-07-11 | Smith Kline French Lab | Anti-arthritic compositions comprising phosphine or phosphite gold halide complexes and methods of producing anti-arthritic activity |
| US3887707A (en) * | 1973-07-23 | 1975-06-03 | Smithkline Corp | Anti-arthritic compositions comprising an S-phosphine or phosphite gold thio-cyanate and methods of producing anti-arthritic activity |
| US4275059A (en) * | 1977-03-28 | 1981-06-23 | The Procter & Gamble Company | Salicylate anti-inflammatory composition |
| NL175882C (nl) * | 1977-03-28 | Procter & Gamble | Farmaceutisch preparaat, dat een verbinding met ontstekingtegengaande werking bevat. | |
| US4216212A (en) * | 1978-06-08 | 1980-08-05 | The Procter & Gamble Company | Pyrazolidine anti-inflammatory composition and methods of use |
| US4282214A (en) * | 1978-07-31 | 1981-08-04 | The Procter & Gamble Company | Phenylacetate anti-inflammatory composition |
| US4264582A (en) * | 1978-07-31 | 1981-04-28 | The Procter & Gamble Company | Isobutylphenylacetate anti-inflammatory composition |
| US4330530A (en) * | 1980-12-22 | 1982-05-18 | The Procter & Gamble Company | Anti-arthritic compositions and method using gold salts and organophosphonates |
| FR2531088B1 (fr) * | 1982-07-29 | 1987-08-28 | Sanofi Sa | Produits anti-inflammatoires derives de l'acide methylenediphosphonique et leur procede de preparation |
| FR2558837B1 (fr) * | 1984-01-26 | 1986-06-27 | Sanofi Sa | Derives de l'acide methylenediphosphonique, procede d'obtention et medicaments antirhumatismaux les contenant |
| DE3428524A1 (de) * | 1984-08-02 | 1986-02-13 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| US5104863A (en) * | 1984-12-21 | 1992-04-14 | The Procter & Gamble Company | Certain bicycloalkane and azabicycloalkane-1,1-diphosphonic acid derivatives useful for treating diseases associated with abnormal calcium and phosphate metabolism |
| IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
| US4687768A (en) * | 1984-12-21 | 1987-08-18 | The Procter & Gamble Company | Certain hexahydroindan-2,2-diphosphonic acids useful in treating diseases associated with abnormal calcium and phosphate metabolism |
| DE3776880D1 (de) * | 1986-11-21 | 1992-04-02 | Ciba Geigy Ag | Neue substituierte alkandiphosphonsaeuren. |
| US5071840A (en) * | 1986-12-19 | 1991-12-10 | Norwich Eaton Pharmaceuticals, Inc. | Certain heterocyclic substituted diphosphonate compounds pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism |
| US4868164A (en) * | 1986-12-19 | 1989-09-19 | Norwich Eaton Pharmaceuticals, Inc. | Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism |
| IL86951A (en) * | 1987-07-06 | 1996-07-23 | Procter & Gamble Pharma | Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them |
| EP0320455B1 (de) * | 1987-12-11 | 1993-06-09 | Ciba-Geigy Ag | Araliphatylaminoalkandiphosphonsäuren |
| DE3808039A1 (de) * | 1988-03-10 | 1989-09-21 | Bauer Johann | Kombinationspraeparat, insbesondere zur behandlung von entzuendlichen prozessen |
| TW198039B (ko) * | 1988-11-28 | 1993-01-11 | Ciba Geigy Ag | |
| DE4011777A1 (de) * | 1989-04-14 | 1990-10-18 | Ciba Geigy Ag | N-trisubstituierte aminoalkandiphosphonsaeuren |
-
1993
- 1993-06-14 WO PCT/US1993/005627 patent/WO1994000130A1/en active IP Right Grant
- 1993-06-14 RU RU94046311A patent/RU2119794C1/ru active
- 1993-06-14 EP EP93914470A patent/EP0650361B1/en not_active Expired - Lifetime
- 1993-06-14 JP JP6502408A patent/JPH07508279A/ja active Pending
- 1993-06-14 DE DE69324684T patent/DE69324684T2/de not_active Expired - Fee Related
- 1993-06-14 AU AU44120/93A patent/AU675796B2/en not_active Ceased
- 1993-06-14 NZ NZ253631A patent/NZ253631A/en unknown
- 1993-06-14 HU HU9403763A patent/HUT72437A/hu unknown
- 1993-06-14 DK DK93914470T patent/DK0650361T3/da active
- 1993-06-14 ES ES93914470T patent/ES2133402T3/es not_active Expired - Lifetime
- 1993-06-14 AT AT93914470T patent/ATE179329T1/de not_active IP Right Cessation
- 1993-06-14 SK SK1609-94A patent/SK160994A3/sk unknown
- 1993-06-14 CA CA002138366A patent/CA2138366C/en not_active Expired - Fee Related
- 1993-06-29 MA MA23218A patent/MA22914A1/fr unknown
- 1993-06-30 MX MX9303969A patent/MX9303969A/es unknown
-
1994
- 1994-12-30 KR KR1019940704867A patent/KR950702121A/ko not_active Application Discontinuation
-
1995
- 1995-06-07 US US08/479,787 patent/US5869471A/en not_active Expired - Fee Related
-
1999
- 1999-04-29 GR GR990401010T patent/GR3030076T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2119794C1 (ru) | 1998-10-10 |
| DE69324684D1 (de) | 1999-06-02 |
| AU4412093A (en) | 1994-01-24 |
| JPH07508279A (ja) | 1995-09-14 |
| HU9403763D0 (en) | 1995-02-28 |
| GR3030076T3 (en) | 1999-07-30 |
| CA2138366A1 (en) | 1994-01-06 |
| DE69324684T2 (de) | 1999-11-25 |
| RU94046311A (ru) | 1996-11-10 |
| NZ253631A (en) | 1997-02-24 |
| US5869471A (en) | 1999-02-09 |
| CA2138366C (en) | 1998-09-22 |
| EP0650361A1 (en) | 1995-05-03 |
| ES2133402T3 (es) | 1999-09-16 |
| DK0650361T3 (da) | 1999-06-23 |
| WO1994000130A1 (en) | 1994-01-06 |
| MX9303969A (es) | 1994-04-29 |
| EP0650361B1 (en) | 1999-04-28 |
| SK160994A3 (en) | 1996-01-10 |
| ATE179329T1 (de) | 1999-05-15 |
| AU675796B2 (en) | 1997-02-20 |
| MA22914A1 (fr) | 1993-12-31 |
| HUT72437A (en) | 1996-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR950702121A (ko) | 포스포네이트 및 비스테로이드계 소염 약물(nasid)을 함유하는 관절염 치료 조성물(compositions for the treatment of arthritis containing phosphonates and nsaids) | |
| RU92004521A (ru) | Применение бисфосфонатов и экстракта паращитовидных желез для лечения остеопороза и набор для лечения | |
| CA2124792A1 (en) | Methods for the Treatment of Osteoporosis Using Bisphosphonates and Parathyroid Hormone | |
| RU94046316A (ru) | Применение высокоэффективных фосфонатов при изготовлении лекарственных средств для лечения остеопороза | |
| ATE105482T1 (de) | Behandlung von krebs mit somatostatin und mit analogen davon. | |
| DE3687224D1 (de) | Hemmung vom 5-lipoxygenase-weg. | |
| IL76932A (en) | Synergistic pharmaceutical analgesic compositions containing dihydrocodeine and ibuprofen | |
| NO305581B1 (no) | Anvendelse av et benaktivt fosfonat i kombinasjon med et °strogenhormon, og preparat i enhetsdoseform for behandling av osteoporose | |
| DK0660705T3 (da) | Avanceret lægemiddelafgivelsessystem og fremgangsmåde til behandling af psykiatriske, neurologiske og andre lidelser med ca | |
| GR3015302T3 (en) | Pharmaceutical formulations for preventing drug tolerance. | |
| KR910009273A (ko) | 위장관계 통증 치료용 약제학적 조성물 | |
| KR950702120A (ko) | 골다공증 치료를 위한 포스포네이트의 용도(use of phosphonates for the treatment of osteoporosis) | |
| DE69201660D1 (de) | Verwendung von Acetyl L-Carnitin zur therapeutischen Behandlung von Coma. | |
| DE3480764D1 (de) | Behandlung von anfaellen und hierfuer nuetzliche pharmazeutische zusammensetzungen. | |
| NO962503L (no) | Anvendelse av penoksyfyllin ved behandling av multippel sklerose | |
| NO945059L (no) | Preparater for behandling av artritt inneholdende fosfonater og NSAIDer | |
| AR015275A1 (es) | Bloque de lamer | |
| ATE87482T1 (de) | Pharmazeutische praeparate zur behandlung von zereberalen psycho-organischen syndromen. | |
| KR880009652A (ko) | 3-5-디클로로메토트랙세이트를 사용하는 류마티스성 관절염 치료법 및 그에 유용한 조성물 | |
| Oledzka et al. | Calcium-phosphate balance in rats exposed to carbaryl | |
| NO945058L (no) | Anvendelse av fosfonater for behandling av osteoporose | |
| HUP0004653A2 (hu) | Biszfoszfonátok alkalmazása csontreszorpció gátlására szolgáló gyógyszerkészítmények előállítására | |
| UA15281A (uk) | Спосіб лікуваhhя хроhічhої ішемічhої хвороби серця | |
| BG100116A (bg) | Инвазивен метод за лечение на енкопреза и енурезис ноктурна в комбинация или поотделно | |
| IT1243711B (it) | Uso del solfato di idrazina nel trattamento dei tumori al cervello |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application |