KR950700257A - 콜레시스토키닌 길항제로서 유용한 3-페닐우레이도-아제핀-2-온 및 벤즈아제핀-2-온(3-phenylureido-azepin-2-ones and-benzazepin-2-ones useful as cholecystokinin antagonists) - Google Patents
콜레시스토키닌 길항제로서 유용한 3-페닐우레이도-아제핀-2-온 및 벤즈아제핀-2-온(3-phenylureido-azepin-2-ones and-benzazepin-2-ones useful as cholecystokinin antagonists)Info
- Publication number
- KR950700257A KR950700257A KR1019940702565A KR19940702565A KR950700257A KR 950700257 A KR950700257 A KR 950700257A KR 1019940702565 A KR1019940702565 A KR 1019940702565A KR 19940702565 A KR19940702565 A KR 19940702565A KR 950700257 A KR950700257 A KR 950700257A
- Authority
- KR
- South Korea
- Prior art keywords
- phenyl
- formula
- ureido
- alkyl
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82567792A | 1992-01-27 | 1992-01-27 | |
US825,677 | 1992-01-27 | ||
PCT/US1992/010720 WO1993015059A1 (en) | 1992-01-27 | 1992-12-16 | 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
KR950700257A true KR950700257A (ko) | 1995-01-16 |
Family
ID=25244657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940702565A KR950700257A (ko) | 1992-01-27 | 1992-12-16 | 콜레시스토키닌 길항제로서 유용한 3-페닐우레이도-아제핀-2-온 및 벤즈아제핀-2-온(3-phenylureido-azepin-2-ones and-benzazepin-2-ones useful as cholecystokinin antagonists) |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0625145A1 (de) |
JP (1) | JPH07503465A (de) |
KR (1) | KR950700257A (de) |
CN (1) | CN1074903A (de) |
AU (1) | AU3276193A (de) |
BR (1) | BR9207071A (de) |
CA (1) | CA2117367A1 (de) |
CZ (1) | CZ391092A3 (de) |
FI (1) | FI943513A (de) |
HU (1) | HUT70496A (de) |
IL (1) | IL104472A0 (de) |
MX (1) | MX9300409A (de) |
NO (1) | NO942775L (de) |
NZ (1) | NZ245759A (de) |
RU (1) | RU94038063A (de) |
TW (1) | TW213901B (de) |
WO (1) | WO1993015059A1 (de) |
YU (1) | YU4393A (de) |
ZA (1) | ZA93582B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2097688A1 (es) * | 1993-07-14 | 1997-04-01 | Pfizer | Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas. |
DK0711283T3 (da) * | 1993-07-26 | 1999-11-22 | Pfizer | Tetrahydro-1H-benzazepinoner og hexahydroazepinoner som selektive cholecystokinin-B-receptorantagonister |
ES2162907T3 (es) * | 1993-11-22 | 2002-01-16 | Merck & Co Inc | 3-acilaminobenzacepinas. |
US5453424A (en) * | 1993-11-22 | 1995-09-26 | Merck & Co., Inc. | Furanodiazepines |
CA2200336C (en) * | 1994-10-04 | 2001-12-11 | Pfizer Limited | Processes and intermediates for preparing 3-amino-benzo(b)azepinones |
ES2171196T3 (es) * | 1994-10-14 | 2002-09-01 | Glaxosmithkline Spa | Uso de antagonistas del receptor cck-b para el tratamiento de trastornos del sueño. |
DE10153348A1 (de) | 2001-10-29 | 2003-05-08 | Gruenenthal Gmbh | Substituierte Benzo(b)azepin-2-on-Verbindungen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0166357A3 (de) * | 1984-06-26 | 1988-10-26 | Merck & Co. Inc. | Kondensierte Benzo-Laktame und deren pharmazeutische Zusammensetzungen |
US4767756A (en) * | 1987-07-17 | 1988-08-30 | E. R. Squibb & Sons, Inc. | 3-substituted benzazepines |
EP0322779A3 (de) * | 1987-12-29 | 1991-05-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzolaktam-Verbindungen und deren pharmazeutische Verwendungen |
US5206234A (en) * | 1990-10-22 | 1993-04-27 | Merck & Co., Inc. | Benzolactam analogs as antagonists of cck |
-
1992
- 1992-12-15 TW TW081110044A patent/TW213901B/zh active
- 1992-12-16 BR BR9207071A patent/BR9207071A/pt not_active Application Discontinuation
- 1992-12-16 KR KR1019940702565A patent/KR950700257A/ko not_active Application Discontinuation
- 1992-12-16 AU AU32761/93A patent/AU3276193A/en not_active Abandoned
- 1992-12-16 WO PCT/US1992/010720 patent/WO1993015059A1/en not_active Application Discontinuation
- 1992-12-16 RU RU94038063/04A patent/RU94038063A/ru unknown
- 1992-12-16 JP JP5513196A patent/JPH07503465A/ja active Pending
- 1992-12-16 EP EP93901470A patent/EP0625145A1/de not_active Withdrawn
- 1992-12-16 CA CA002117367A patent/CA2117367A1/en not_active Abandoned
- 1992-12-16 HU HU9402195A patent/HUT70496A/hu unknown
- 1992-12-28 CZ CS923910A patent/CZ391092A3/cs unknown
-
1993
- 1993-01-21 IL IL104472A patent/IL104472A0/xx unknown
- 1993-01-21 CN CN93101158A patent/CN1074903A/zh active Pending
- 1993-01-26 MX MX9300409A patent/MX9300409A/es unknown
- 1993-01-26 YU YU4393A patent/YU4393A/sh unknown
- 1993-01-26 NZ NZ245759A patent/NZ245759A/en unknown
- 1993-01-27 ZA ZA93582A patent/ZA93582B/xx unknown
-
1994
- 1994-07-26 NO NO942775A patent/NO942775L/no unknown
- 1994-07-26 FI FI943513A patent/FI943513A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
FI943513A0 (fi) | 1994-07-26 |
EP0625145A1 (de) | 1994-11-23 |
NZ245759A (en) | 1997-06-24 |
MX9300409A (es) | 1993-07-01 |
CN1074903A (zh) | 1993-08-04 |
BR9207071A (pt) | 1995-12-05 |
RU94038063A (ru) | 1996-05-27 |
NO942775D0 (no) | 1994-07-26 |
NO942775L (no) | 1994-09-20 |
ZA93582B (en) | 1994-07-27 |
JPH07503465A (ja) | 1995-04-13 |
FI943513A (fi) | 1994-07-26 |
AU3276193A (en) | 1993-09-01 |
WO1993015059A1 (en) | 1993-08-05 |
YU4393A (sr) | 1996-01-09 |
TW213901B (de) | 1993-10-01 |
CA2117367A1 (en) | 1993-08-05 |
IL104472A0 (en) | 1993-05-13 |
HUT70496A (en) | 1995-10-30 |
HU9402195D0 (en) | 1994-09-28 |
CZ391092A3 (en) | 1994-01-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |