KR950035305A - 폐 이식조직 보존용 조성물 및 폐 이식조직의 생존 보전방법 - Google Patents

폐 이식조직 보존용 조성물 및 폐 이식조직의 생존 보전방법 Download PDF

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Publication number
KR950035305A
KR950035305A KR1019950001322A KR19950001322A KR950035305A KR 950035305 A KR950035305 A KR 950035305A KR 1019950001322 A KR1019950001322 A KR 1019950001322A KR 19950001322 A KR19950001322 A KR 19950001322A KR 950035305 A KR950035305 A KR 950035305A
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KR
South Korea
Prior art keywords
preserving
lung transplant
transplant tissue
lung
survival
Prior art date
Application number
KR1019950001322A
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English (en)
Inventor
노부요시 시미즈
고우찌 우노
모또이 아오메
겐이찌 요시다
Original Assignee
요시다 쇼오지
센쥬세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 요시다 쇼오지, 센쥬세이야꾸 가부시끼가이샤 filed Critical 요시다 쇼오지
Publication of KR950035305A publication Critical patent/KR950035305A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 하기식의 인산디에스테르 화합물을 포함하는 폐 이식조직 보존용 조성물.
(여기서 R1및 R2는 동일 또는 상이하고 각각은 수소원자 또는 메틸기를 나타낸다)는 약학적으로 허용되는 이의 염 및 이 화합물을 이용한 폐 이식조직의 보존방법을 개시한다.

Description

폐 이식조직 보존용 조성물 및 폐 이식조직의 생존 보존방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 폐 이식후 동맥혈 산소의 분압을 나타낸다. 종축은 동맥혈 산소의 분압(PaO2)(단위 : ㎜Hg)을 나타내고, 횡축은 폐 이식후의 시간(단위 : 시간)을 나타낸다. 제2도는 폐 이식후 동맥혈 이산화탄소의 분압을 나타낸다. 종축은 동맥혈 이산화탄소의 분압(PaO2)(단위 : ㎜Hg)을 나타내고, 횡축은 폐 이식후의 시간(단위 : 시간)을 나타낸다. 제3도는 폐 이식후 혈관외의 폐수(lung water)를 나타낸다. 종축은 혈관외의 폐수(EVLW)(단위ml/kg)를 나타내고, 횡축은 폐 이식후 시간(단위 : 시간)을 나타낸다. 종축은 혈액 단란 비율(단위 : %)을 나타내고, 횡축은 폐 이식후 시간(단위 : 시간)을 나타내고, 제5도는 폐 이식후 폐의 혈관 저항을 나타낸다. 종축은 폐의 혈관 저항(PVR)(단위 : dyne/sec/cm5)을 나타내고, 횡축은 폐 이식후 시간(단위 : 시간)을 나타낸다.

Claims (2)

  1. 폐 보전에 유효한 양의 하기식의 인산 디에스테르 화합물 또는 약리적으로 허용되는 이의 염을 포함하는 폐 이식조직 보존용 조성물.
    (여기서 R1및 R2는 동일 또는 상이하고 각각 수소원자 또는 메틸기를 나타낸다).
  2. 제1항에서 청구된 인산 디에스테르 화합물 또는 약리적으로 허용되는 염을 사용함을 특징으로 하는 폐이식조직의 생존 보전방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950001322A 1994-01-28 1995-01-25 폐 이식조직 보존용 조성물 및 폐 이식조직의 생존 보전방법 KR950035305A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6008237A JPH07215801A (ja) 1994-01-28 1994-01-28 肺保存剤および肺保存方法
JP94-8237 1994-01-28

Publications (1)

Publication Number Publication Date
KR950035305A true KR950035305A (ko) 1995-12-30

Family

ID=11687550

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950001322A KR950035305A (ko) 1994-01-28 1995-01-25 폐 이식조직 보존용 조성물 및 폐 이식조직의 생존 보전방법

Country Status (9)

Country Link
US (1) US5556842A (ko)
EP (1) EP0664953B1 (ko)
JP (1) JPH07215801A (ko)
KR (1) KR950035305A (ko)
AT (1) ATE179300T1 (ko)
CA (1) CA2139547A1 (ko)
DE (1) DE69509268T2 (ko)
ES (1) ES2132439T3 (ko)
TW (1) TW287086B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162450A (en) * 1995-05-15 2000-12-19 Avon Products, Inc. Uses of ascorbyl-phosphoryl-cholesterol and compositions for practicing same
US5922335A (en) * 1995-05-15 1999-07-13 Avon Products, Inc. Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
JPH0984853A (ja) * 1995-09-22 1997-03-31 Material Eng Tech Lab Inc 臓器保存液を収容した医療用容器
JP3623294B2 (ja) 1995-11-28 2005-02-23 株式会社新素材総合研究所 電解質液が収容された医療用容器及びその製造方法
FR2975869B1 (fr) * 2011-05-31 2017-03-03 Hemarina Composition de preservation d'organe et utilisations
BR102014002362A8 (pt) * 2014-01-30 2018-04-17 Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs método de imunomodulação e/ou preservação de órgãos ex-vivo, composições, processo e usos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59219295A (ja) * 1983-05-30 1984-12-10 Senjiyu Seiyaku Kk リン酸ジエステルまたはその塩およびそれらの製造法
JPS62205091A (ja) * 1986-03-04 1987-09-09 Senjiyu Seiyaku Kk 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
JPH0781138B2 (ja) * 1986-12-02 1995-08-30 株式会社資生堂 抗酸化剤
PH25859A (en) * 1988-01-11 1991-12-02 Takeda Chemical Industries Ltd Composition for treatment of ischemic disorder
US4939128A (en) * 1988-04-25 1990-07-03 Takeda Chemical Industries, Ltd. Ester of ascorbic acid 2-phosphate and pharmaceutical use
CH683485A5 (fr) * 1990-11-20 1994-03-31 Pasteur Merieux Serums Vacc Solutions de perfusion, de conservation et de reperfusion d'organes.
TW262386B (ko) * 1992-09-30 1995-11-11 Senju Pharma Co

Also Published As

Publication number Publication date
US5556842A (en) 1996-09-17
ATE179300T1 (de) 1999-05-15
TW287086B (ko) 1996-10-01
JPH07215801A (ja) 1995-08-15
DE69509268D1 (de) 1999-06-02
EP0664953B1 (en) 1999-04-28
CA2139547A1 (en) 1995-07-29
DE69509268T2 (de) 1999-10-14
ES2132439T3 (es) 1999-08-16
EP0664953A1 (en) 1995-08-02

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