KR950032633A - 낮은 다분자성 인덱스의 전분 가수분해물의 제조방법, 신규 전분 가수분해물의 획득과 복막 투석에서 용도 - Google Patents
낮은 다분자성 인덱스의 전분 가수분해물의 제조방법, 신규 전분 가수분해물의 획득과 복막 투석에서 용도 Download PDFInfo
- Publication number
- KR950032633A KR950032633A KR1019950002662A KR19950002662A KR950032633A KR 950032633 A KR950032633 A KR 950032633A KR 1019950002662 A KR1019950002662 A KR 1019950002662A KR 19950002662 A KR19950002662 A KR 19950002662A KR 950032633 A KR950032633 A KR 950032633A
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- Prior art keywords
- less
- hydrolyzate
- starch hydrolyzate
- low
- starch
- Prior art date
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- 229920002472 Starch Polymers 0.000 title claims abstract 15
- 239000008107 starch Substances 0.000 title claims abstract 15
- 235000019698 starch Nutrition 0.000 title claims abstract 15
- 238000000034 method Methods 0.000 title claims abstract 6
- 238000000502 dialysis Methods 0.000 title claims abstract 3
- 239000011347 resin Substances 0.000 claims abstract description 4
- 229920005989 resin Polymers 0.000 claims abstract description 4
- 125000002091 cationic group Chemical group 0.000 claims abstract description 3
- 238000004587 chromatography analysis Methods 0.000 claims abstract 3
- 239000002253 acid Substances 0.000 claims abstract 2
- 238000005903 acid hydrolysis reaction Methods 0.000 claims abstract 2
- 230000007071 enzymatic hydrolysis Effects 0.000 claims abstract 2
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 claims abstract 2
- 235000013336 milk Nutrition 0.000 claims abstract 2
- 239000008267 milk Substances 0.000 claims abstract 2
- 210000004080 milk Anatomy 0.000 claims abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 3
- 239000008103 glucose Substances 0.000 claims 3
- 238000011210 chromatographic step Methods 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 1
- 150000001342 alkaline earth metals Chemical class 0.000 claims 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
- 102000004139 alpha-Amylases Human genes 0.000 claims 1
- 108090000637 alpha-Amylases Proteins 0.000 claims 1
- 229940024171 alpha-amylase Drugs 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000006317 isomerization reaction Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/16—Apparatus therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/287—Dialysates therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P2201/00—Pretreatment of cellulosic or lignocellulosic material for subsequent enzymatic treatment or hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01001—Alpha-amylase (3.2.1.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
본 발명은 특히 연속적이고 통원의 복막 투석에 사용될 수 있는 낮은 다분자성 인덱스의 전분 가수분해물의 제조방법에 관한 것이다.
이 방법은 실제로 왁스상 전분 밀크의 산 및 효소 가수분해 및 그후 얻어진 가수분해물의 거시공 강양이온성 수지에서 크로마토 그래피로 구성된다. 전분 가수분해물은 실제로 2.8 이하의 다분자성 인덱스, 5,000-22, 5000 달톤의 중량-평균 분자량 및 8,000 달톤 이하의 수-평균 분자량을 특징으로 한다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명에서 사용되는 PUROLITE사에 의해 시판된 C 150거시공 강양이온성 수지로서 충전된, 각각 200리터의 8개 컬럼 또는 단계 C1-C8로 이루어진 연속적인 크로마토그래피 장치의 개략도, 제2도는 제1도에 도시된 개략도의 상세도.
Claims (7)
- D.E. 8-15 이하로 왁스상 전분 밀크의 산 가수분해; 임의로 박테리아 알파-아밀라제를 이용하여 D.E. 11-18 이하로 이와 같이 얻어진 산 가수분해물의 효소 가수분해; 알칼리 금속 또는 알칼리-토금속 형태로 거시공 강양이온성 수지에서 이와 같이 얻어진 가수분해물의 크로마토그래피; 이 크로마토그래피 단계 중에 배제된 전분 가수분해물의 수집으로 구성된 것이 특징인, 낮은 다분자성 인덱스의 전분 가수분해물의 제조방법.
- 제1항에 있어서, 낮은 다분자성 인덱스의 전분 가수분해물의 중량 수율이 크로마토그래피 단계에서 사용된 가수분해물의 10-80%인 것이 특징인 제조방법.
- 제1또는 2항에 있어서, 크로마토그래피를 칼륨 형태의 수지에서 수행하는 것이 특징인 제조방법.
- 제1-3항중 어느 한 항에 있어서, 배제된 전분 가수분해물을 촉매 수소화 또는 환원 단부를 트레할로스로 변형하는 효소 이성체화로 구성된 열 안정화 단계에 수행하는 것이 특징인 제조방법.
- 왁스상 전분 가수분해물이 2.8 이하 및 바람직하게는 2.5 이하의 다분자성 인덱스, 8,000-22,500 달톤 및 바람직하게는 12,000-20,000달톤의 중량-평균 분자량 Mw 및 8,000달톤 이하의 수-평균 분자량 Mn을 가지는 것이 특징인, 임의로 수소화 또는 이성체화된, 완전 가용성 및 낮은 다분자성 인덱스의 왁스상 전분 가수분해물.
- 제5항에 있어서, 글루코스와 3 이하 또는 이와 동일한 D.P.의 글루코스 폴리머의 3% 이하, 및 600 이상의 D.P.의 글루코스 폴리머 0.5% 이하를 함유하는 것이 특징인 전분 가수분해물.
- 연속적이고 통원의 복막 투석에 사용될 침투제를 얻기 위하여 제5또는 6항에 따른 낮은 다분자성 인덱스의 전분 가수분해물의 적용.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9401707A FR2716199B1 (fr) | 1994-02-15 | 1994-02-15 | Procédé de fabrication d'un hydrolysat d'amidon à faible indice de polymolécularité, nouvel hydrolysat d'amidon ainsi obtenu et son utilisation en dialyse péritonéale. |
| FR94-01707 | 1994-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR950032633A true KR950032633A (ko) | 1995-12-22 |
Family
ID=9460096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019950002662A KR950032633A (ko) | 1994-02-15 | 1995-02-14 | 낮은 다분자성 인덱스의 전분 가수분해물의 제조방법, 신규 전분 가수분해물의 획득과 복막 투석에서 용도 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5837060A (ko) |
| EP (1) | EP0667356B1 (ko) |
| JP (1) | JP3983826B2 (ko) |
| KR (1) | KR950032633A (ko) |
| AT (1) | ATE167875T1 (ko) |
| AU (1) | AU685555B2 (ko) |
| CA (1) | CA2142528C (ko) |
| DE (1) | DE69503157T2 (ko) |
| DK (1) | DK0667356T3 (ko) |
| ES (1) | ES2117837T3 (ko) |
| FI (1) | FI110004B (ko) |
| FR (1) | FR2716199B1 (ko) |
| NO (1) | NO306904B1 (ko) |
| ZA (1) | ZA951104B (ko) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9810127D0 (en) | 1998-05-13 | 1998-07-08 | Ml Lab Plc | Prevention of surgical adhesions |
| CN1150034C (zh) | 1998-08-24 | 2004-05-19 | 黑川清 | 羰基压力改善剂和腹膜透析液 |
| FR2786775B1 (fr) * | 1998-12-04 | 2001-02-16 | Roquette Freres | Maltodextrines branchees et leur procede de preparation |
| JP4510184B2 (ja) * | 1999-08-27 | 2010-07-21 | 小川香料株式会社 | 粉末香料の製造方法 |
| FR2815822B1 (fr) | 2000-10-30 | 2004-08-27 | Roquette Freres | Additif carbone pour fermentations alimentaires et compositions alimentaires le contenant |
| CN1125085C (zh) * | 2000-11-08 | 2003-10-22 | 福州大学 | 一种糊精的制造方法及其装置 |
| FR2822645B1 (fr) * | 2001-03-30 | 2005-03-11 | Roquette Freres | Composition pour nutrition enterale comprenant des fibres |
| FR2840612B1 (fr) † | 2002-06-06 | 2005-05-06 | Roquette Freres | Polymeres solubles de glucose hautement branches et leur procede d'obtention |
| US7118857B2 (en) | 2004-02-27 | 2006-10-10 | Baxter International Inc. | Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions |
| FR2871155B1 (fr) * | 2004-06-02 | 2007-04-27 | Roquette Freres | Utilisation de polysaccharides particuliers pour l'adjuvantation de matieres minerales |
| JPWO2006115067A1 (ja) * | 2005-04-20 | 2008-12-18 | 株式会社林原生物化学研究所 | 腹膜透析液 |
| WO2006125286A1 (en) * | 2005-05-24 | 2006-11-30 | Getec Guanabara Química Industrial S.A. | Process for the production of pyrogen-free anhydrous crystalline dextrose of high purity from sucrose |
| JP5164340B2 (ja) * | 2006-05-10 | 2013-03-21 | フタムラ化学株式会社 | 易ゲル化デンプン部分分解物 |
| FR2945043B1 (fr) | 2009-04-30 | 2019-07-26 | Roquette Freres | Procede de purification de polymeres de glucose destines aux solutions de dialyse peritoneale |
| JP2011130696A (ja) * | 2009-12-24 | 2011-07-07 | Nihon Cornstarch Corp | マルトデキストリンの製造方法 |
| FR2955861B1 (fr) | 2010-02-02 | 2013-03-22 | Roquette Freres | Polymeres solubles de glucose branches pour la dialyse peritoneale |
| CN103732233B (zh) * | 2011-03-18 | 2016-08-10 | 贝克斯特国际公司 | 包含葡萄糖聚合物的腹膜透析溶液 |
| SG194005A1 (en) | 2011-04-08 | 2013-11-29 | Roquette Freres | Methods for detecting contaminants in solutions containing glucose polymers |
| US20150125871A1 (en) * | 2012-05-29 | 2015-05-07 | Roquette Freres | Methods for decontaminating circuits for producing glucose polymers and hydrolysates of glucose polymers |
| EP3119813B1 (fr) * | 2014-03-21 | 2023-01-04 | Roquette Frères | Procede optimise de decontamination de production de polymeres de glucose et d'hydrolysats de polymeres de glucose |
| FR3037063B1 (fr) | 2015-06-04 | 2017-05-19 | Roquette Freres | Procede optimise de decontamination de l'amidon utilise comme matiere premiere pour l'obtention de polymeres de glucose destines a la dialyse peritoneale |
| CN106397616B (zh) * | 2016-08-30 | 2019-10-18 | 华南理工大学 | 一种淀粉基腹膜透析液用艾考糊精的制备方法 |
| CN114316076B (zh) * | 2020-09-29 | 2023-01-31 | 青岛力腾医药科技有限公司 | 一种肾病用源于淀粉的麦芽糖糊精的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1203048A (en) * | 1966-12-19 | 1970-08-26 | Corn Products Co | Low d.e. starch hydrolysate composition, syrup, and syrup solids and process for producing the same |
| US3974032A (en) * | 1973-03-05 | 1976-08-10 | Cpc International Inc. | Low D.E. starch hydrolysates of improved stability prepared by enzymatic hydrolysis of dextrins |
| GB8300718D0 (en) * | 1983-01-12 | 1983-02-16 | Milner Research Ireland Ltd | Glucose polymer solutions |
| FR2575179B1 (fr) * | 1984-12-20 | 1987-02-06 | Roquette Freres | Procede de preparation de maltitol cristallise |
| EP0207676B1 (en) * | 1985-06-22 | 1994-06-01 | M L Laboratories Plc | Polymers for use in continuous peritoneal dialysis |
| JP2926434B2 (ja) * | 1990-07-26 | 1999-07-28 | 株式会社林原生物化学研究所 | アミロース粒子とその製造方法 |
| DE4132701A1 (de) * | 1991-10-01 | 1993-04-08 | Laevosan Gmbh & Co Kg | Verfahren zur herstellung von staerkeabbauprodukten mit einer engen molekulargewichtsverteilung |
| FR2688793B1 (fr) * | 1992-03-19 | 1994-06-03 | Roquette Freres | Composition de saccharides hydrogenes hypocariogenes, procede de preparation et application de cette composition. |
| FR2697023B1 (fr) * | 1992-10-16 | 1994-12-30 | Roquette Freres | Polymère soluble hypocalorique du glucose et procédé de préparation de ce polymère . |
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1994
- 1994-02-15 FR FR9401707A patent/FR2716199B1/fr not_active Expired - Fee Related
-
1995
- 1995-02-10 ZA ZA951104A patent/ZA951104B/xx unknown
- 1995-02-13 DK DK95400292T patent/DK0667356T3/da active
- 1995-02-13 FI FI950614A patent/FI110004B/fi not_active IP Right Cessation
- 1995-02-13 ES ES95400292T patent/ES2117837T3/es not_active Expired - Lifetime
- 1995-02-13 AU AU12223/95A patent/AU685555B2/en not_active Expired
- 1995-02-13 DE DE69503157T patent/DE69503157T2/de not_active Expired - Lifetime
- 1995-02-13 EP EP95400292A patent/EP0667356B1/fr not_active Expired - Lifetime
- 1995-02-13 AT AT95400292T patent/ATE167875T1/de active
- 1995-02-14 CA CA002142528A patent/CA2142528C/en not_active Expired - Lifetime
- 1995-02-14 NO NO950546A patent/NO306904B1/no not_active IP Right Cessation
- 1995-02-14 JP JP02567795A patent/JP3983826B2/ja not_active Expired - Lifetime
- 1995-02-14 KR KR1019950002662A patent/KR950032633A/ko not_active Application Discontinuation
-
1998
- 1998-01-06 US US09/003,130 patent/US5837060A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI110004B (fi) | 2002-11-15 |
| NO950546D0 (no) | 1995-02-14 |
| ES2117837T3 (es) | 1998-08-16 |
| DE69503157D1 (de) | 1998-08-06 |
| FI950614A (fi) | 1995-08-16 |
| DE69503157T2 (de) | 1999-01-21 |
| ZA951104B (en) | 1996-02-12 |
| US5837060A (en) | 1998-11-17 |
| EP0667356A1 (fr) | 1995-08-16 |
| ATE167875T1 (de) | 1998-07-15 |
| CA2142528C (en) | 2008-07-15 |
| NO306904B1 (no) | 2000-01-10 |
| FR2716199A1 (fr) | 1995-08-18 |
| DK0667356T3 (da) | 1999-04-12 |
| CA2142528A1 (en) | 1995-08-16 |
| NO950546L (no) | 1995-08-16 |
| JP3983826B2 (ja) | 2007-09-26 |
| JPH0885701A (ja) | 1996-04-02 |
| FI950614A0 (fi) | 1995-02-13 |
| FR2716199B1 (fr) | 1996-04-26 |
| EP0667356B1 (fr) | 1998-07-01 |
| AU685555B2 (en) | 1998-01-22 |
| AU1222395A (en) | 1995-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |