KR950031061A - 과반응성 염증 질환 치료용 약제를 제조하기 위한 데옥시스페르구알린의 용도 - Google Patents
과반응성 염증 질환 치료용 약제를 제조하기 위한 데옥시스페르구알린의 용도 Download PDFInfo
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- KR950031061A KR950031061A KR1019950005896A KR19950005896A KR950031061A KR 950031061 A KR950031061 A KR 950031061A KR 1019950005896 A KR1019950005896 A KR 1019950005896A KR 19950005896 A KR19950005896 A KR 19950005896A KR 950031061 A KR950031061 A KR 950031061A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
본 발명은 사람 및 동물의 과반응성 염증 질환 치료용 및 예방용 약제를 제조하기 위한 데옥시스페르구알린의 용도에 관한 것이다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 데옥시스페르구알린(DSG)을 투여량-의존 방법으로 투여함으로써 경동맥의 동맥경화성 병변에 의한 동맥내막의 신생(the formation of neointima)이 현저히 억제됨을 나타낸다.
Claims (9)
- 과반응성 염증 질환 치료용 및 예방용 약제를 제조하기 위한 데옥시스페르구알린의 용도.
- 제1항에 있어서, 활성 입체이성체를 사용하는 용도.
- 제1항에 있어서, 질환이 만성 염증 장 질환, 과반응성 장해성 기도 질환, 만성 염증 혈관 질환 또는 뇌의 만성 감염 질환인 용도.
- 제1항에 있어서, 질환이 궤양성대장염, 천식, 동맥경화, 췌장염, 패혈증 또는 알쯔하이머 질환인 용도.
- 제1항에 있어서, 추가의 활성 화합물과 배합물이 제조되는 용도.
- 제1항에 있어서, 메트로니다졸과의 배합물이 제조되는 용도.
- 제1항에 있어서, 데옥시스페르구알린을 함유하는 약제가 0.1 내지 100㎎/㎏용량으로 제조되는 용도.
- 제1항에 있어서, 약제가 경구, 정맥내, 피하, 피부내, 복막내,포막내, 눈내, 눈, 볼, 비강, 경피, 피부, 국소, 흡입, 근육내 또는 직장 투여용으로 제조되는 용도.
- 제1항에 있어서, 약제가 정맥내 또는 경구 투여용으로 제조되는 용도.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4409804A DE4409804A1 (de) | 1994-03-22 | 1994-03-22 | Verwendung von Deoxyspergualin zur Herstellung eines Arzneimittels zur Behandlung von entzündlich-hyperreaktiven Erkrankungen |
DEP4409804.9 | 1994-03-22 | ||
DEP4415553.0 | 1994-05-03 | ||
DE19944415553 DE4415553A1 (de) | 1994-05-03 | 1994-05-03 | Verwendung von Deoxyspergualin zur Herstellung eines Arzneimittels zur Behandlung von entzündlich-hyperreaktiven Erkrankungen |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950031061A true KR950031061A (ko) | 1995-12-18 |
KR100338579B1 KR100338579B1 (ko) | 2002-11-23 |
Family
ID=25934947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950005896A KR100338579B1 (ko) | 1994-03-22 | 1995-03-21 | 데옥시스페르구알린을함유하는과반응성염증성질환치료용약제학적조성물 |
Country Status (11)
Country | Link |
---|---|
US (1) | US5849799A (ko) |
EP (1) | EP0673646B1 (ko) |
JP (2) | JP3483646B2 (ko) |
KR (1) | KR100338579B1 (ko) |
AT (1) | ATE173921T1 (ko) |
AU (1) | AU712361B2 (ko) |
CA (1) | CA2145211C (ko) |
DE (1) | DE59504374D1 (ko) |
DK (1) | DK0673646T3 (ko) |
ES (1) | ES2124926T3 (ko) |
NZ (1) | NZ270749A (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6294581B1 (en) * | 1998-05-15 | 2001-09-25 | Takara Shuzo Co., Ltd. | Inhibition of IgA production |
DE19923961A1 (de) * | 1999-05-25 | 2000-11-30 | Euro Nippon Kayaku Gmbh | Verwendung von 15-Deoxyspergualin zur Behandlung von hyperreaktiven entzündlichen Erkrankungen und Autoimmunerkrankungen |
US20030166732A1 (en) * | 2002-02-27 | 2003-09-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity |
JP2006117569A (ja) * | 2004-10-20 | 2006-05-11 | Juntendo | ステロイド依存性あるいはステロイド抵抗性潰瘍性大腸炎治療薬 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4851446A (en) * | 1984-11-13 | 1989-07-25 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Immunosuppressing method |
JPS61134312A (ja) * | 1984-12-06 | 1986-06-21 | Microbial Chem Res Found | 移植免疫抑制剤並びに抗アレルギ−剤 |
DE3626306A1 (de) * | 1986-08-02 | 1988-02-11 | Behringwerke Ag | Verwendung von 15-deoxyspergualin als arzneimittel |
GB9126870D0 (en) * | 1991-12-18 | 1992-02-19 | Fujisawa Pharmaceutical Co | Novel compound |
US5238689A (en) * | 1992-01-07 | 1993-08-24 | Procept, Inc. | Use of ruthenium red as immunosuppressive agents |
GB9203265D0 (en) * | 1992-02-15 | 1992-04-01 | Fisons Plc | Pharmaceutically active compound |
DE4329503A1 (de) * | 1993-09-01 | 1995-03-02 | Galenik Labor Freiburg Gmbh | Pharmazeutische Präparate zur gezielten Behandlung von Morbus Crohn und Colitis Ulcerosa |
-
1995
- 1995-03-10 ES ES95103470T patent/ES2124926T3/es not_active Expired - Lifetime
- 1995-03-10 DK DK95103470T patent/DK0673646T3/da active
- 1995-03-10 EP EP95103470A patent/EP0673646B1/de not_active Expired - Lifetime
- 1995-03-10 DE DE59504374T patent/DE59504374D1/de not_active Expired - Lifetime
- 1995-03-10 AT AT95103470T patent/ATE173921T1/de active
- 1995-03-20 AU AU14943/95A patent/AU712361B2/en not_active Ceased
- 1995-03-20 NZ NZ270749A patent/NZ270749A/en not_active IP Right Cessation
- 1995-03-20 US US08/406,406 patent/US5849799A/en not_active Expired - Lifetime
- 1995-03-21 CA CA002145211A patent/CA2145211C/en not_active Expired - Fee Related
- 1995-03-21 KR KR1019950005896A patent/KR100338579B1/ko not_active IP Right Cessation
- 1995-03-22 JP JP06317795A patent/JP3483646B2/ja not_active Expired - Fee Related
-
2003
- 2003-05-06 JP JP2003127757A patent/JP2003286160A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2003286160A (ja) | 2003-10-07 |
KR100338579B1 (ko) | 2002-11-23 |
ES2124926T3 (es) | 1999-02-16 |
CA2145211A1 (en) | 1995-09-23 |
EP0673646A3 (de) | 1995-12-27 |
CA2145211C (en) | 2002-10-15 |
EP0673646B1 (de) | 1998-12-02 |
ATE173921T1 (de) | 1998-12-15 |
EP0673646A2 (de) | 1995-09-27 |
JPH0840887A (ja) | 1996-02-13 |
US5849799A (en) | 1998-12-15 |
AU1494395A (en) | 1995-09-28 |
DE59504374D1 (de) | 1999-01-14 |
NZ270749A (en) | 1997-03-24 |
JP3483646B2 (ja) | 2004-01-06 |
DK0673646T3 (da) | 1999-08-16 |
AU712361B2 (en) | 1999-11-04 |
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