KR950025021A - 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트 - Google Patents

페닐-1,2-에탄디올 광학이성체의 단일 카바메이트 Download PDF

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Publication number
KR950025021A
KR950025021A KR1019940003071A KR19940003071A KR950025021A KR 950025021 A KR950025021 A KR 950025021A KR 1019940003071 A KR1019940003071 A KR 1019940003071A KR 19940003071 A KR19940003071 A KR 19940003071A KR 950025021 A KR950025021 A KR 950025021A
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KR
South Korea
Prior art keywords
carbamoyloxy
ethanediol
phenyl
phenylethanol
optical isomers
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Application number
KR1019940003071A
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English (en)
Other versions
KR100197901B1 (ko
Inventor
변재국
최용문
김민우
Original Assignee
조규향
주식회사 유공
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Application filed by 조규향, 주식회사 유공 filed Critical 조규향
Priority to KR1019940003071A priority Critical patent/KR100197901B1/ko
Publication of KR950025021A publication Critical patent/KR950025021A/ko
Application granted granted Critical
Publication of KR100197901B1 publication Critical patent/KR100197901B1/ko

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

본 발명은 (R)- 또는 (S)-페닐-1,2-에탄디올의 단일 카바메이트에 관한 것으로서, 좀 더 상세하게는 (R)-2-카바모일옥시-1-페닐에탄올, (R)-2-카바모일옥시-2-페닐에탄올, (S)-2-카바모일옥시-1-페닐에탄올, (S)-2-카바모일옥시-2-페닐에탄올 4종에 관한 것이다.
본 발명에 따른 광학이성질체는 중추신경계 질병, 예를 들어 신경성 근육통, 간질 및 뇌졸중의 치료 또는 예방에 유용하다.

Description

페닐-1,2-에탄디올 광학이성체의 단일 카바메이트
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 하기 구조식(I)로 표시되는 (R)-2-카바모일옥시-1-페닐에탄올.
  2. 하기 구조식(II)로 표시되는 (R)-2-카바모일옥시-2-페닐에탄올.
  3. 하기 구조식(III)으로 표시되는 (S)-2-카바모일옥시-1-페닐에탄올.
  4. 하기 구조식(IV)으로 표시되는 (S)-2-카바모일옥시-1-페닐에탄올.
  5. 하기 구조식(V)로 표시되는 (R)-페닐-1,2-에탄디올 시클릭카보네이트.
  6. 하기 구조식(VI)로 표시되는 (S)-페닐-1,2-에탄디올 시클릭카보네이트.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940003071A 1994-02-21 1994-02-21 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트 KR100197901B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019940003071A KR100197901B1 (ko) 1994-02-21 1994-02-21 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019940003071A KR100197901B1 (ko) 1994-02-21 1994-02-21 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트

Publications (2)

Publication Number Publication Date
KR950025021A true KR950025021A (ko) 1995-09-15
KR100197901B1 KR100197901B1 (ko) 1999-06-15

Family

ID=19377511

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940003071A KR100197901B1 (ko) 1994-02-21 1994-02-21 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트

Country Status (1)

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KR (1) KR100197901B1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
KR101717871B1 (ko) * 2013-03-12 2017-03-20 (주)바이오팜솔루션즈 페닐카바메이트 화합물 및 이를 포함하는 기억 손실-관련 질환의 예방 또는 치료용 조성물
CN109939092B (zh) * 2013-03-12 2022-03-22 比皮艾思药物研发有限公司 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物

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KR100197901B1 (ko) 1999-06-15

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